Zobrazeno 61 - 70
of 73
pro vyhledávání: ''
Autor:
Filippo Casoni, Paolo Giacobini, Päivi Lahermo, Eeva-Marja Sankila, Johanna Känsäkoski, Marita Lipsanen-Nyman, Emily J Lodge, Riikka Keski-Filppula, Kari Kaunisto, Xiaonan Liu, Jørgen K. Kanters, Kristiina Pulli, Tal Buki, Mitja Lääperi, Johanna Tommiska, Riitta Veijola, Mari A. Kaunisto, Joel A. Hirsch, Lei Yuan, Sirpa Kivirikko, Tapani Ebeling, Patrice Mollard, Franziska Phan-Hug, Lasse Skibsbye, Sanna Vuoristo, Kirsi Vaaralahti, Taneli Raivio, Cynthia L. Andoniadou, Manuel Tena-Sempere, Thomas Jespersen, Nelly Pitteloud, Chuyi Tang, Rainer Fagerholm, Leena Valanne, Markku Varjosalo
Publikováno v:
Nature Communications
Tommiska, J, Känsäkoski, J, Skibsbye, L, Vaaralahti, K, Liu, X, Lodge, E J, Tang, C, Yuan, L, Fagerholm, R, Kanters, J K, Lahermo, P, Kaunisto, M, Keski-Filppula, R, Vuoristo, S, Pulli, K, Ebeling, T, Valanne, L, Sankila, E-M, Kivirikko, S, Lääperi, M, Casoni, F, Giacobini, P, Phan-Hug, F, Buki, T, Tena-Sempere, M, Pitteloud, N, Veijola, R, Lipsanen-Nyman, M, Kaunisto, K, Mollard, P, Andoniadou, C L, Hirsch, J A, Varjosalo, M, Jespersen, T & Raivio, T 2017, ' Two missense mutations in KCNQ1 cause pituitary hormone deficiency and maternally inherited gingival fibromatosis ', Nature Communications, vol. 8, no. 1, 1289 . https://doi.org/10.1038/s41467-017-01429-z
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature communications, vol. 8, no. 1, pp. 1289
Tommiska, J, Känsäkoski, J, Skibsbye, L, Vaaralahti, K, Liu, X, Lodge, E J, Tang, C, Yuan, L, Fagerholm, R, Kanters, J K, Lahermo, P, Kaunisto, M, Keski-Filppula, R, Vuoristo, S, Pulli, K, Ebeling, T, Valanne, L, Sankila, E-M, Kivirikko, S, Lääperi, M, Casoni, F, Giacobini, P, Phan-Hug, F, Buki, T, Tena-Sempere, M, Pitteloud, N, Veijola, R, Lipsanen-Nyman, M, Kaunisto, K, Mollard, P, Andoniadou, C L, Hirsch, J A, Varjosalo, M, Jespersen, T & Raivio, T 2017, ' Two missense mutations in KCNQ1 cause pituitary hormone deficiency and maternally inherited gingival fibromatosis ', Nature Communications, vol. 8, no. 1, 1289 . https://doi.org/10.1038/s41467-017-01429-z
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature communications, vol. 8, no. 1, pp. 1289
Familial growth hormone deficiency provides an opportunity to identify new genetic causes of short stature. Here we combine linkage analysis with whole-genome resequencing in patients with growth hormone deficiency and maternally inherited gingival f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f65b757cd3eec6b9407f896b92ee41
http://urn.fi/urn:nbn:fi-fe2019081223873
http://urn.fi/urn:nbn:fi-fe2019081223873
Autor:
Katsushi Kumata, Makoto Higuchi, Masahiko Takada, Hiroyuki Kaneko, Mark A.G. Eldridge, Yasuyuki Kimura, Ichio Aoki, Ken-ichi Inoue, Barry J. Richmond, Yukiko Hori, Atsushi Fujimoto, Erika Kikuchi, Yoko Kato, Yuji Nagai, Tetsuya Suhara, Takafumi Minamimoto, Ming-Rong Zhang, Toshiyuki Hirabayashi, Arata Oh-Nishi, Walter Lerchner, Bin Ji
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Nature Communications
Nature Communications
The rostromedial caudate (rmCD) of primates is thought to contribute to reward value processing, but a causal relationship has not been established. Here we use an inhibitory DREADD (Designer Receptor Exclusively Activated by Designer Drug) to repeat
Autor:
Naosuke Nakamura, Yukinori Hirano, Yusuke Suzuki, Tomoko Masuda, Ikuko Iwata, Minoru Saitoe, Takuya Yamamoto, Hiroko Awata, Kunio Ihara, Mai Takakura, Junjiro Horiuchi, Hiroyuki Okuno, Aya Takahashi
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Nature Communications
Nature Communications
Accumulating evidence suggests that transcriptional regulation is required for maintenance of long-term memories (LTMs). Here we characterize global transcriptional and epigenetic changes that occur during LTM storage in the Drosophila mushroom bodie
Autor:
Antoni Bautista-Barrufet, Amadeu Llebaria, Pedro de la Villa, Alejandro García-Moll, Eduardo Fernández, Sergio Valbuena, Carles Rodríguez-Escrich, Aida Garrido-Charles, Ariadna Díaz-Tahoces, Ana Trapero, Mercè Izquierdo-Serra, Pau Gorostiza, Juan Lerma, Ariadna Pérez-Jiménez, Núria Camarero, Silvia Pittolo, Miquel A. Pericàs
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
ResearcherID
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
ResearcherID
Light-regulated drugs allow remotely photoswitching biological activity and enable plausible therapies based on small molecules. However, only freely diffusible photochromic ligands have been shown to work directly in endogenous receptors and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb3037fd9b5ddafa0422bf24ebfe0415
http://hdl.handle.net/10261/177712
http://hdl.handle.net/10261/177712
Autor:
Javier Rangel-Moreno, Shabaana A. Khader, Kristin L. Griffiths, Maxim N. Artyomov, Terry D. Connell, Mushtaq Ahmed, Shibali Das, Jay K. Kolls, Kelly D. Moynihan, William Horne, Radha Gopal, Darrell J. Irvine
Publikováno v:
Nature
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Nature Communications
The development of a tuberculosis (TB) vaccine that induces sterilizing immunity to Mycobacterium tuberculosis infection has been elusive. Absence of sterilizing immunity induced by TB vaccines may be due to delayed activation of mucosal dendritic ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0039a941640f2f8f9ece4994982f1a14
http://hdl.handle.net/1721.1/107719
http://hdl.handle.net/1721.1/107719
Autor:
Natàlia Reixach, Salvador Ventura, Raul Insa, Ricardo Sant'Anna, Oscar Huertas, David Reverter, Adrián Velázquez-Campoy, Lei Z. Robinson, Sebastian Esperante, Nelson Ferreira, Maria Rosário Almeida, Pablo Gallego, Alda Pereira-Henriques, Irantzu Pallarès, Francisca Pinheiro, Núria Reig
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Zaguán. Repositorio Digital de la Universidad de Zaragoza
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature Communications
instname
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Zaguán. Repositorio Digital de la Universidad de Zaragoza
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature Communications
13 pags, 6 figs, 1 tab. -- Supplementary information is available at the Publisher's web
Transthyretin (TTR) is a plasma homotetrameric protein implicated in fatal systemic amyloidoses. TTR tetramer dissociation precedes pathological TTR aggrega
Transthyretin (TTR) is a plasma homotetrameric protein implicated in fatal systemic amyloidoses. TTR tetramer dissociation precedes pathological TTR aggrega
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64234fcfaf7f7adcb8d807ac4da4df1f
http://hdl.handle.net/10261/255695
http://hdl.handle.net/10261/255695
Autor:
Patrik Andersson, Yangang Wang, Masaki Nakamura, Xuri Li, Takahiro Seki, Yunlong Yang, Masato Miyake, Fang Chen, Yizhi Liu, Seiichi Oyadomari, Jun Zhang, Carina Fischer, Yanyan Gao, Yihai Cao, Jennifer Honek, Sharon Lim, Yun Zhang, Akihiro Yasue, Nilesh J. Samani
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-19 (2017)
Nature Communications
Nature Communications
Understanding the molecular mechanisms regulating beige adipocyte formation may lead to the development of new therapies to combat obesity. Here, we report a miRNA-based autocrine regulatory pathway that controls differentiation of preadipocytes into
Autor:
Emi Yamasaki, Tetsuhiro Kikuchi, Sayuki Takara, Hirohito Ishigaki, Hisashi Doi, Daisuke Doi, Kazumasa Ogasawara, Asuka Morizane, Hiroshi Mizuma, Hirotaka Onoe, Keisuke Okita, Matthew F. Glasser, Takashi Shiina, Shinya Yamanaka, Yasushi Itoh, Aya Mawatari, Takuya Hayashi, Jun Takahashi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications
Nature Communications
The banking of human leukocyte antigen (HLA)-homozygous-induced pluripotent stem cells (iPSCs) is considered a future clinical strategy for HLA-matched cell transplantation to reduce immunological graft rejection. Here we show the efficacy of major h
Autor:
Jonathan T. Eggenschwiler, Cullen Timmons, Jie Li, Andrew T. Sornborger, Yousuke Takahama, Floria I. Lupu, Nancy R. Manley
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications
Nature Communications
While many tools exist for identifying and quantifying individual cell types, few methods are available to assess the relationships between cell types in organs and tissues and how these relationships change during aging or disease states. We present
Autor:
Eriko Nango, Mika K. Kaneko, Yuko Kusakabe, Yukiyo Nomura, Atsuko Yamashita, Shuji Akiyama, Junichi Takagi, Norihisa Yasui, Maiko Hosotani, Yukinari Kato, Nanako Atsumi, Nipawan Nuemket
Publikováno v:
SC10201804160071
NARO成果DBa
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications
NARO成果DBa
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications
The taste receptor type 1 (T1r) family perceives ‘palatable' tastes. These receptors function as T1r2-T1r3 and T1r1-T1r3 heterodimers to recognize a wide array of sweet and umami (savory) tastes in sugars and amino acids. Nonetheless, it is unclear