Zobrazeno 51 - 60
of 223
pro vyhledávání: ''
Autor:
Lianghai Wang, Jinfang Jiang, Feng Li, Jianming Hu, Hongwei Dang, Xiaobin Cui, Na Li, Weihua Liang, Yue-xun Xu, Yong Li, Shu-Mao Zhang, Chunxia Liu, Lan Yang, Yunzhao Chen
Publikováno v:
Journal of Translational Medicine
Background Esophageal squamous cell carcinoma (ESCC) is one of the most aggressively malignant tumors with dismal prognosis. Profilin 2 (PFN2) is an actin-binding protein that regulates the dynamics of actin polymerization and plays a key role in cel
Autor:
Jaana Hagström, Kapo Saukkonen, Caj Haglund, Pauliina Kallio, Harri Mustonen, Anne Juuti, Hanna Seppänen, Stig Nordling, Kari Alitalo
Publikováno v:
BMC Cancer
Background The Wnt/β-catenin pathway has a key role in regulating cellular processes and its aberrant signaling can lead to cancer development. The role of β-catenin expression in pancreatic ductal adenocarcinoma is somewhat controversial. Transcri
Autor:
Li, Qin, Zhang, Lei, Li, XiuHong, Yan, Han, Yang, Liuting, Li, Yingying, Li, Teng, Wang, Jing, Cao, Bangwei
Publikováno v:
BMC Cancer
Background Prognostic factors aid in the stratification and treatment of cancer. This study evaluated the prognostic significance of human epidermal growth factor receptor (HER) family members (HER1–4) expression in patients with operable pancreati
Publikováno v:
BMC Cancer
BMC Cancer, Vol 10, Iss 1, p 650 (2010)
BMC Cancer, Vol 10, Iss 1, p 650 (2010)
Background Human papillomavirus (HPV) infection is a major risk factor for the development of nearly all cases of cervical cancer worldwide. The presence of HPV DNA in cases of esophageal squamous-cell carcinoma (ESCC) has been reported repeatedly fr
Publikováno v:
BMC Cancer
Background Although mammary microcalcification is frequently observed and has been associated with poor survival in patients with breast cancer, the genesis of calcification remains unclear. Carbonic anhydrase I (CA1) has been shown to promote calcif
Publikováno v:
BMC Cancer
Background FoxC2 is an epithelial–mesenchymal transition (EMT) regulator which induces metastasis. The purpose of this study is to assess the prognostic value of FoxC2 expression in non-small cell lung cancer (NSCLC), alone or in combination with E
Autor:
Rita Barros, Joana Vieira, Patrícia Castro, Ricardo Celestino, Raquel Almeida, Fátima Carneiro, Leonor David, Manuel R. Teixeira, Vânia Camilo, João Pinto-de-Sousa
Publikováno v:
BMC Cancer
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Background Gastric cancer remains a serious health concern worldwide. Patients would greatly benefit from the discovery of new biomarkers that predict outcome more accurately and allow better treatment and follow-up decisions. Here, we used a retrosp
Autor:
Sandra Zazo, Maria Soengas, Aurea Borrero-Palacios, A. Puime-Otin, Irene Moreno, María Rodríguez-Remírez, Javier Martinez-Useros, Jesús García-Foncillas, Teresa Gómez del Pulgar, Ricardo Vega-Bravo, Federico Rojo, María Jesús Fernández-Aceñero, Arancha Cebrián, Laura del Puerto-Nevado, Nuria Perez, Clara Senin
Publikováno v:
BMC Cancer
Background DEK is a transcription factor involved in stabilization of heterochromatin and cruciform structures. It plays an important role in development and progression of different types of cancer. This study aims to analyze the role of DEK in meta
Autor:
Takehiro Wakasugi, Hideyuki Ishiguro, Hiromitsu Takeyama, Nobuhiro Sakamoto, Hiroyuki Sagawa, Tatsuya Tanaka, Tomotaka Okubo, Yukio Terashita
Publikováno v:
Cellular & Molecular Biology Letters
The prognosis for patients with esophageal cancer remains poor. Therefore, the identification of novel target molecules for the treatment of esophageal cancer is necessary. Here, we investigated the clinicopathological significance of transcription f
Autor:
Adrienne Morey, Diana J. Hastrich, David Ingram, Peter C. Willsher, Arlene Chan, Belinda Brown
Publikováno v:
BMC Cancer, Vol 12, Iss 1, p 555 (2012)
BMC Cancer
BMC Cancer
Background Overall survival of HER2 positive metastatic breast cancer patients has been significantly improved with inclusion of trastuzumab to chemotherapy. Several studies have demonstrated discordant HER2 status in the primary and metastatic tumou