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of 129
pro vyhledávání: ''
Autor:
Dirkje W. Sommeijer, Matthew T. Seymour, Lianne Koens, Cornelis J. A. Punt, Sanne ten Hoorn, David Fisher, Tim Maughan, Louis Vermeulen, Faye Elliott, Anne Trinh, Phil Quirke, Susan D. Richman, Jenny F. Seligmann, Tim R. de Back, Richard Adams
Publikováno v:
British Journal of Cancer
British journal of cancer, 125(8), 1080-1088. Nature Publishing Group
British journal of cancer, 125(8), 1080-1088. Nature Publishing Group
Background Patient selection for addition of anti-EGFR therapy to chemotherapy for patients with RAS and BRAF wildtype metastatic colorectal cancer can still be optimised. Here we investigate the effect of anti-EGFR therapy on survival in different c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329765bd38bc4fb86b004b51f8c16428
https://eprints.whiterose.ac.uk/176152/6/s41416-021-01477-9.pdf
https://eprints.whiterose.ac.uk/176152/6/s41416-021-01477-9.pdf
Autor:
Mari K. Halle, Marte Sødal, Hilde Engerud, David Forsse, Bjørn I. Bertelsen, Camilla Krakstad, Ingfrid S. Haldorsen, Kari Strøno Wagner-Larsen, Njål G. Lura, Jone Trovik, Kathrine Woie, Akinyemi I. Ojesina
Publikováno v:
British Journal of Cancer
Background Advanced cervical cancer carries a particularly poor prognosis, and few treatment options exist. Identification of effective molecular markers is vital to improve the individualisation of treatment. We investigated transcriptional data fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839b54a851051f73e14419c2d53c21d6
https://hdl.handle.net/11250/2830881
https://hdl.handle.net/11250/2830881
Autor:
Miguel Gil-Gil, José A. García-Sáenz, E Dalmau Portulas, Elena García-Martínez, Nuria Ribelles, A. Santaballa Bertran, E. Martínez de Dueñas, I Alvarez-Lopez, Susana Bezares
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Clinical & Translational Oncology
Universidad de Barcelona
Clinical & Translational Oncology
PurposeHormone receptor (HR)-positive, Human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer (MBC) requires a therapeutic approach that takes into account multiple factors, with treatment being based on anti-estrogen hormo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b63a263cb82f360402dddafab187eefb
http://hdl.handle.net/2445/174389
http://hdl.handle.net/2445/174389
Autor:
Caroline Kreuzinger, Jalid Sehouli, Silvia Darb-Esfahani, Ignace Vergote, Mandy Stanske, Elena Ioana Braicu, Ilary Ruscito, Alexander Mustea, Iulia Ignat, Hani Gabra, Dan Cacsire Castillo-Tong, Mirjana Kessler, Pierluigi Benedetti Panici, Hagen Kulbe, Jacek Glajzer, Adriaan Vanderstichele, Marianna Nuti, Charlie Gourley, Fabian Trillsch, Eliane T Taube
Publikováno v:
British Journal of Cancer
Ruscito, I, Cacsire Castillo-Tong, D, Vergote, I, Ignat, I, Stanske, M, Vanderstichele, A, Glajzer, J, Kulbe, H, Trillsch, F, Mustea, A, Kreuzinger, C, Benedetti Panici, P, Gourley, C, Gabra, H, Nuti, M, Taube, E T, Kessler, M, Sehouli, J, Darb-Esfahani, S & Ioana Braicu, E 2018, ' Characterisation of tumor microvessel density during progression of high-grade serous ovarian cancer: clinico-pathological impact. An OCTIPS Consortium study. ', British Journal of Cancer . https://doi.org/10.1038/s41416-018-0157-z
Ruscito, I, Cacsire Castillo-Tong, D, Vergote, I, Ignat, I, Stanske, M, Vanderstichele, A, Glajzer, J, Kulbe, H, Trillsch, F, Mustea, A, Kreuzinger, C, Benedetti Panici, P, Gourley, C, Gabra, H, Nuti, M, Taube, E T, Kessler, M, Sehouli, J, Darb-Esfahani, S & Ioana Braicu, E 2018, ' Characterisation of tumor microvessel density during progression of high-grade serous ovarian cancer: clinico-pathological impact. An OCTIPS Consortium study. ', British Journal of Cancer . https://doi.org/10.1038/s41416-018-0157-z
BACKGROUND: High-grade serous ovarian cancer (HGSOC) intratumoural vasculature evolution remains unknown. The study investigated changes in tumour microvessel density (MVD) in a large cohort of paired primary and recurrent HGSOC tissue samples and it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a40b9d4b6a3397f76d0ea77556e6a859
http://hdl.handle.net/10044/1/70613
http://hdl.handle.net/10044/1/70613
Publikováno v:
Medical Oncology (Northwood, London, England)
We had reported that MSP58 regulates colorectal cancer cell proliferation, development, and apoptosis, by the cyclin D1-cyclin-dependent kinase 4-p21 pathway. In this study, MSP58 protein expression was examined by immunohistochemistry in 499 specime
Autor:
Fumitake Kubo, Kazuhiro Abeyama, Ikuro Maruyama, Takashi Aikou, Shoji Natsugoe, Kiyokazu Hiwatashi, Masahiro Hamanoue, Masahiko Sakoda, Shinichi Ueno
Publikováno v:
Annals of Surgical Oncology
Background The expression of the receptor for advanced glycation end products (RAGE) has an impact on the mechanisms giving rise to characteristic features of various cancer cells. The purpose of this study was to elucidate the clinicopathological re
Autor:
Mauro Piacentini, Matteo Marconi, Steno Sentinelli, Michele Gallucci, Walter Malorni, Laura Falasca, Vincenzo Pompeo, Cristiano Padula, Manuela Costantini, Francesco Torino, Mario Patrizio, Laura De Salvo
Publikováno v:
Apoptosis
Prostate cancer is among the most commonly diagnosed male diseases and a leading cause of cancer mortality in men. There is emerging evidence that autophagy plays an important role in malignant cell survival and offers protection from the anti-cancer
Autor:
Olaf Glueck, Thomas Schweiger, Denise Traxler, Christoph Glogner, Orsolya Rajky, Peter Birner, Anna S. Berghoff, Walter Klepetko, Matthias Preusser, Konrad Hoetzenecker
Publikováno v:
Clinical & Experimental Metastasis
The presence of tumor-infiltrating lymphocytes (TILs) and tertiary lymphoid structures (TLSs) reflects an active inflammatory tumor microenvironment. High density of TILs as well as presence of TLS is associated with improved survival in various soli
Autor:
Kym Pham, Peter Gibbs, Thomas M. Grogan, Fiona Day, Jayesh Desai, Oliver M. Sieber, Jeanne Tie, Paul Waring, Kandavel Shanmugam, Shalini Singh, David J Byrne, Andrea Muranyi, Michelle Palmieri, David S. Williams
Publikováno v:
Targeted Oncology
The B-type Raf kinase (BRAF) V600E mutation is a well-established biomarker for poor prognosis in metastatic colorectal cancer (mCRC) and is a highly attractive drug target. A barrier to the development of new therapies targeting BRAF V600E in mCRC i
Publikováno v:
World Journal of Surgery
Background Better prognostic markers are needed for pancreatic endocrine tumors. Survivin is an apoptosis inhibitor that is suggested to have a negative prognostic impact in several tumor types. Contradictory data exist, especially regarding the sign