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Autor:
Hisashi Motomura, Wataru Goto, Shinichiro Kashiwagi, Yuka Asano, Shuhei Tomita, Koji Takada, Masahiko Ohsawa, Katsuyuki Takahashi, Kosei Hirakawa, Masaichi Ohira, Tsutomu Takashima, Takaharu Hatano
Publikováno v:
British Journal of Cancer
Background Immune responses in a tumour microenvironment can be evaluated by analysing tumour-infiltrating lymphocyte (TIL) density; this has been verified in the clinical setting. Although there are many reports on TIL density in primary tumours, li
Autor:
Andrzej Sygut, Julia Kruk-Jeromin, Ireneusz Majsterek, Adam Dziki, Grażyna Pasz-Walczak, Jan Rykała, Karolina Przybyłowska
Publikováno v:
Pathology Oncology Research
Tumoural angiogenesis is essential for the growth and spread of breast cancer cells. Therefore the aim of this study was to assess the diagnostic performance of angiogenesis markers in tumours and there reflecting levels in serum of breast cancer pat
Autor:
J. van Gorp, Th. van Dalen, E. V. E. Madsen, P. de Hooge, Paul D. Gobardhan, D. Geertsema, M. Albregts
Publikováno v:
Annals of Surgical Oncology
Background In breast cancer surgery, intraoperative frozen section (FS) analysis of sentinel lymph nodes (SLNs) enables axillary lymph node dissection (ALND) during the same operative procedure. In case of discordance between a “negative” FS anal
Autor:
Fabio Corradini, Francesco Piva, Riccardo Cellerino, C. Brugiati, R. Bracci, Eva Galizia, Italo Bearzi, Alessandra Viel, L. Belvederesi, Diana Baralle, Francesca Bianchi, Michela Raponi, Cristian Loretelli
Publikováno v:
Familial Cancer
Single base substitutions can lead to missense mutations, silent mutations or intronic mutations, whose significance is uncertain. Aberrant splicing can occur due to mutations that disrupt or create canonical splice sites or splicing regulatory seque
Publikováno v:
Breast Cancer Research and Treatment
Breast Cancer Research and Treatment, 151(1), 41. Springer New York
Breast Cancer Research and Treatment, 151(1), 41. Springer New York
Promoter hypermethylation of tumor suppressor genes seems to be an early event in breast carcinogenesis and is potentially reversible. This makes methylation a possible therapeutic target, a marker for treatment response and/or a prognostic factor. M
Autor:
Xavier Gonzalez, Miguel Caballero, Carlos Caso, Albert Biete, Araceli Rodriguez, G. Zanon, Juan J. Grau
Publikováno v:
Annals of Surgical Oncology
Background Many women covered by the Spanish public health system also have an extra private insurance policy for gynecological examinations and routine annual mammography. We retrospectively analyzed the long-term survival rates in these patients wh
Autor:
Pawel Jozwiak, Anna Krzeslak, Hanna Romanowicz, Katarzyna Wójcik-Krowiranda, Ewa Forma, Andrzej Bieńkiewicz, Magdalena Brys
Publikováno v:
Pathology Oncology Research
Cancer cells have accelerated metabolism and high glucose requirements. The up-regulation of specific glucose transporters may represent a key mechanism by which malignant cells may achieve increased glucose uptake to support the high rate of glycoly
Autor:
Isabella Castellano, Fulvia Pedani, Paola Cassoni, Anna Sapino, Simona Osella-Abate, Michela Donadio, Mario Airoldi, Mauro Papotti, Sara Bustreo
Publikováno v:
Breast Cancer Research and Treatment
Although Ki67 index suffers from poor reproducibility, it is one of the most important prognostic markers used by oncologists to select the treatment of estrogen receptor (ER) positive breast cancer patients. In this study, we aim to establish the op
Autor:
Lisette Stork-Sloots, Paul Richards, Stephanie Akbari, Femke A. de Snoo, Mark A. Gittleman, Jennifer Beatty, Charles Nash, Laura A. Lee, Danielle Boselli, Angela Mislowsky, Mary Murray, James T. Symanowski, Peter D. Beitsch, Pat Whitworth, Paul L. Baron, James Pellicane
Publikováno v:
Annals of Surgical Oncology
Background The prospective Neoadjuvant Breast Symphony Trial (NBRST) study found that MammaPrint/BluePrint functional molecular subtype is superior to conventional immunohistochemistry/fluorescence in situ hybridization subtyping for predicting patho
Autor:
Shirley W. Flatt, Cynthia A. Thomson, Vicky A. Newman, Ruth E. Patterson, Lisa A. Cadmus Bertram, Cheryl L. Rock, Nazmus Saquib, Wayne A. Bardwell, John P. Pierce, Loki Natarajan, Marcia L. Stefanick
Publikováno v:
Cancer Causes & Control
Cancer causes & control : CCC, vol 22, iss 3
Cancer causes & control : CCC, vol 22, iss 3
Objective Research suggests that physical activity is associated with improved breast cancer survival, yet no studies have examined the association between post-diagnosis changes in physical activity and breast cancer outcomes. The aim of this study