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of 205
pro vyhledávání: ''
Autor:
Stephan Hutter, Alexander Höllein, Luca Vincenzo Cappelli, Constance Baer, Frank Dicker, Claudia Haferlach, Niroshan Nadarajah, Torsten Haferlach, Sabine Jeromin, Wolfgang Kern, Manja Meggendorfer
Publikováno v:
Leukemia
In AML patients, recurrent mutations were shown to persist in remission, however, only some have a prognostic value and persistent mutations might therefore reflect a re-established premalignant state or truly active disease causing relapse. We aimed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4415d542870701311e8257fb4fbbfe
http://hdl.handle.net/11573/1645705
http://hdl.handle.net/11573/1645705
Autor:
Chun Chieh Fan, Alicja Wolk, Ole A. Andreassen, Anders M. Dale, Karen Tye, Niclas Håkansson, Wesley K. Thompson, Tyler M. Seibert, Kenneth W. Muir, Artitaya Lophatananon, Ian G. Mills, Minh-Phuong Huynh-Le, Roshan Karunamuni
Publikováno v:
Prostate cancer and prostatic diseases
Background: Clinical variables—age, family history, genetics—are used for prostate cancer risk stratification. Recently, polygenic hazard scores (PHS46, PHS166) were validated as associated with age at prostate cancer diagnosis. While polygenic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a072590957b808907129b50c2565ca7c
https://ora.ox.ac.uk/objects/uuid:c6a81563-cdd6-4cd7-bfd5-7d624e2c35b0
https://ora.ox.ac.uk/objects/uuid:c6a81563-cdd6-4cd7-bfd5-7d624e2c35b0
Autor:
Mari K. Halle, Marte Sødal, Hilde Engerud, David Forsse, Bjørn I. Bertelsen, Camilla Krakstad, Ingfrid S. Haldorsen, Kari Strøno Wagner-Larsen, Njål G. Lura, Jone Trovik, Kathrine Woie, Akinyemi I. Ojesina
Publikováno v:
British Journal of Cancer
Background Advanced cervical cancer carries a particularly poor prognosis, and few treatment options exist. Identification of effective molecular markers is vital to improve the individualisation of treatment. We investigated transcriptional data fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839b54a851051f73e14419c2d53c21d6
https://hdl.handle.net/11250/2830881
https://hdl.handle.net/11250/2830881
Autor:
Fotios Loupakis, Sara Lonardi, Chiara Cremolini, Afsaneh Barzi, Yuji Miyamoto, Shivani Soni, Satoshi Okazaki, Marta Schirripa, Mitsukuni Suenaga, Wu Zhang, Toshiharu Yamaguchi, Shu Cao, Martin D. Berger, Heinz-Josef Lenz, Alfredo Falcone
Colorectal cancer (CRC) can be classified into subtypes based on gene expression signatures. Patients with stage III enterocyte subtype of the CRC Assigner classifier have been shown to benefit from oxaliplatin adjuvant therapy. Here, we investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ff7e6de5b6fd5cfca1baeea302a15d
Autor:
Naomi E. Allen, Georgina K. Fensom, Eleanor L. Watts, Ruth C. Travis, Mieke Van Hemelrijck, Timothy J. Key, Richard M. Martin, Colm Andrews, Aurora Perez-Cornago
Publikováno v:
British Journal of Cancer
Perez-Cornago, A, Fensom, G K, Andrews, C, Watts, E L, Allen, N E, Martin, R M, Van Hemelrijck, M, Key, T J & Travis, R C 2020, ' Examination of potential novel biochemical factors in relation to prostate cancer incidence and mortality in UK Biobank ', British Journal of Cancer, vol. 123, pp. 1808–1817 (2020) . https://doi.org/10.1038/s41416-020-01081-3
Perez-Cornago, A, Fensom, G K, Andrews, C, Watts, E L, Allen, N E, Martin, R M, Van Hemelrijck, M, Key, T J & Travis, R C 2020, ' Examination of potential novel biochemical factors in relation to prostate cancer incidence and mortality in UK Biobank ', British Journal of Cancer, vol. 123, pp. 1808–1817 (2020) . https://doi.org/10.1038/s41416-020-01081-3
Background Although prostate cancer is a leading cause of cancer death, its aetiology is not well understood. We aimed to identify novel biochemical factors for prostate cancer incidence and mortality in UK Biobank. Methods A range of cardiovascular,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf7d748a9840dbaf378b95a2ae6734c3
https://doi.org/10.1038/s41416-020-01081-3
https://doi.org/10.1038/s41416-020-01081-3
Autor:
Miguel Gil-Gil, José A. García-Sáenz, E Dalmau Portulas, Elena García-Martínez, Nuria Ribelles, A. Santaballa Bertran, E. Martínez de Dueñas, I Alvarez-Lopez, Susana Bezares
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Clinical & Translational Oncology
Universidad de Barcelona
Clinical & Translational Oncology
PurposeHormone receptor (HR)-positive, Human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer (MBC) requires a therapeutic approach that takes into account multiple factors, with treatment being based on anti-estrogen hormo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b63a263cb82f360402dddafab187eefb
http://hdl.handle.net/2445/174389
http://hdl.handle.net/2445/174389
Autor:
Udo Bavendiek, Robert Geffers, Maximilian Brandes, Timon Seeger, Arnold Ganser, Michael Heuser, Joerg Heineke, David John, Brigitte Schlegelberger, Piroska Klement, Razif Gabdoulline, Abel Martin Garrido, Felicitas Thol, Johann Bauersachs, Gudrun Göhring, Amir Shirvani, Badder Kattih, Anuhar Chaturvedi, Alessandro Liebich
Publikováno v:
Leukemia
Clonal hematopoiesis of indeterminate potential (CHIP) is linked to leukemia gene mutations and associates with an increased risk for coronary artery disease and poor prognosis in ischemic cardiomyopathy. Two recurrently mutated genes in CHIP and adu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2024100c560082a18b7bc28f0645166
https://hdl.handle.net/10033/622512
https://hdl.handle.net/10033/622512
Autor:
Haase, D, Stevenson, KE, Neuberg, D, Maciejewski, JP, Nazha, A, Sekeres, MA, Ebert, BL, Garcia-Manero, G, Haferlach, C, Haferlach, T, Kern, W, Ogawa, S, Nagata, Y, Yoshida, K, Graubert, TA, Walter, MJ, List, AF, Komrokji, RS, Padron, E, Sallman, D, Papaemmanuil, E, Campbell, PJ, Savona, MR, Seegmiller, A, Adès, L, Fenaux, P, Shih, L-Y, Bowen, D, Groves, MJ, Tauro, S, Fontenay, M, Kosmider, O, Bar-Natan, M, Steensma, D, Stone, R, Heuser, M, Thol, F, Cazzola, M, Malcovati, L, Karsan, A, Ganster, C, Hellström-Lindberg, E, Boultwood, J, Pellagatti, A, Santini, V, Quek, L, Vyas, P, Tüchler, H, Greenberg, PL, Bejar, R, Committee, International Working Group For Mds Molecular Prognostic
Publikováno v:
Leukemia
Leukemia, vol 33, iss 7
Leukemia, vol 33, iss 7
Risk stratification is critical in the care of patients with myelodysplastic syndromes (MDS). Approximately 10% have a complex karyotype (CK), defined as more than two cytogenetic abnormalities, which is a highly adverse prognostic marker. However, C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d49797d5f17dd3791db8ac57149af6e
https://ora.ox.ac.uk/objects/uuid:e9f86a5f-8ced-4bb7-944f-fa27fc2c2541
https://ora.ox.ac.uk/objects/uuid:e9f86a5f-8ced-4bb7-944f-fa27fc2c2541
Autor:
Caroline Kreuzinger, Jalid Sehouli, Silvia Darb-Esfahani, Ignace Vergote, Mandy Stanske, Elena Ioana Braicu, Ilary Ruscito, Alexander Mustea, Iulia Ignat, Hani Gabra, Dan Cacsire Castillo-Tong, Mirjana Kessler, Pierluigi Benedetti Panici, Hagen Kulbe, Jacek Glajzer, Adriaan Vanderstichele, Marianna Nuti, Charlie Gourley, Fabian Trillsch, Eliane T Taube
Publikováno v:
British Journal of Cancer
Ruscito, I, Cacsire Castillo-Tong, D, Vergote, I, Ignat, I, Stanske, M, Vanderstichele, A, Glajzer, J, Kulbe, H, Trillsch, F, Mustea, A, Kreuzinger, C, Benedetti Panici, P, Gourley, C, Gabra, H, Nuti, M, Taube, E T, Kessler, M, Sehouli, J, Darb-Esfahani, S & Ioana Braicu, E 2018, ' Characterisation of tumor microvessel density during progression of high-grade serous ovarian cancer: clinico-pathological impact. An OCTIPS Consortium study. ', British Journal of Cancer . https://doi.org/10.1038/s41416-018-0157-z
Ruscito, I, Cacsire Castillo-Tong, D, Vergote, I, Ignat, I, Stanske, M, Vanderstichele, A, Glajzer, J, Kulbe, H, Trillsch, F, Mustea, A, Kreuzinger, C, Benedetti Panici, P, Gourley, C, Gabra, H, Nuti, M, Taube, E T, Kessler, M, Sehouli, J, Darb-Esfahani, S & Ioana Braicu, E 2018, ' Characterisation of tumor microvessel density during progression of high-grade serous ovarian cancer: clinico-pathological impact. An OCTIPS Consortium study. ', British Journal of Cancer . https://doi.org/10.1038/s41416-018-0157-z
BACKGROUND: High-grade serous ovarian cancer (HGSOC) intratumoural vasculature evolution remains unknown. The study investigated changes in tumour microvessel density (MVD) in a large cohort of paired primary and recurrent HGSOC tissue samples and it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a40b9d4b6a3397f76d0ea77556e6a859
http://hdl.handle.net/10044/1/70613
http://hdl.handle.net/10044/1/70613
Autor:
Kalliopi-Maria Tasopoulou, John R. Gosney, Urszula Oleksiewicz, John K. Field, Nikoleta Daskoulidou, George Xinarianos, Triantafillos Liloglou
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Purpose Collagen 1A1 (COL1A1), RNA-binding and pre-mRNA Processing Factor (PRPF40A), and Uncoupling Protein 2 (UCP2) were identified as downstream effectors of cytoglobin (CYGB), which was shown implicated in tumour biology. Although these three gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd17463b8fa8b770a70625ad4ead91f0