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Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Scientific Reports
Progress in understanding the complexity of a devastating disease such as cancer has underscored the need for developing comprehensive panels of molecular markers for early disease detection and precision medicine applications. The present study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c6999b0faba50194b29ac42fa622b8
https://hdl.handle.net/10919/86493
https://hdl.handle.net/10919/86493
Autor:
Beverley S. Speight, Marc Tischkowitz
Publikováno v:
Journal of Genetic Counseling
Germline mutations in BRCA1/BRCA2 significantly increase the risk of breast and ovarian cancer in women. This case report describes a BRCA1 germline mutation identified in a woman with stage IV epithelial ovarian cancer and the provision of genetic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b90b871eb5876d60696048fbb8078c6
https://www.repository.cam.ac.uk/handle/1810/267347
https://www.repository.cam.ac.uk/handle/1810/267347
Autor:
Frank Kee, Antonia Trichopoulou, José María Huerta, Heinz Freisling, Christina Bamia, Mazda Jenab, Paolo Boffetta, Anne Tjønneland, Ellen Kampman, Isabelle Romieu, Hendrik B. Bueno-de-Mesquita, Melina Arnold, Vassiliki Benetou, Hermann Brenner, Mark G. O'Doherty, Konstantinos K. Tsilidis, Tom Wilsgaard, Isabelle Soerjomataram, José M Ordóñez-Mena, Michael F. Leitzmann
Publikováno v:
British Journal of Cancer, 116, 11, pp. 1486-1497
British Journal of Cancer 116 (2017) 11
Freisling, H, Arnold, M, Soerjomataram, I, O'Doherty, M G, Ordóñez-Mena, J M, Bamia, C, Kampman, E, Leitzmann, M, Romieu, I, Kee, F, Tsilidis, K K, Tjønneland, A, Trichopoulou, A, Boffetta, P, Benetou, V, Bueno-de-Mesquita, H B A, Huerta, J M, Brenner, H, Wilsgaard, T & Jenab, M 2017, ' Comparison of general obesity and measures of body fat distribution in older adults in relation to cancer risk: meta-analysis of individual participant data of seven prospective cohorts in Europe ', British Journal of Cancer . https://doi.org/10.1038/bjc.2017.106
British Journal of Cancer, 116(11), 1486-1497
British Journal of Cancer, 116, 1486-1497
British Journal of Cancer
British Journal of Cancer 116 (2017) 11
Freisling, H, Arnold, M, Soerjomataram, I, O'Doherty, M G, Ordóñez-Mena, J M, Bamia, C, Kampman, E, Leitzmann, M, Romieu, I, Kee, F, Tsilidis, K K, Tjønneland, A, Trichopoulou, A, Boffetta, P, Benetou, V, Bueno-de-Mesquita, H B A, Huerta, J M, Brenner, H, Wilsgaard, T & Jenab, M 2017, ' Comparison of general obesity and measures of body fat distribution in older adults in relation to cancer risk: meta-analysis of individual participant data of seven prospective cohorts in Europe ', British Journal of Cancer . https://doi.org/10.1038/bjc.2017.106
British Journal of Cancer, 116(11), 1486-1497
British Journal of Cancer, 116, 1486-1497
British Journal of Cancer
BACKGROUND: We evaluated the associations of anthropometric indicators of general obesity (body mass index, BMI), an established risk factor of various cancer, and body fat distribution (waist circumference, WC; hip circumference, HC; and waist-to-hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09418e44d11a7f89e07058f346ca9f8a
http://hdl.handle.net/10044/1/49276
http://hdl.handle.net/10044/1/49276
Autor:
Liisa M. Pelttari, Paula Poikonen-Saksela, Kristiina Aittomäki, Päivi Auvinen, Arja Jukkola-Vuorinen, Sanna Hallamies, Heli Nevanlinna, Johanna Mattson, Carl Blomqvist, Antti Jekunen
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-5 (2017)
BMC Cancer
BMC Cancer
Background Several susceptibility genes have been established for female breast cancer, of which mutations in BRCA1 and especially in BRCA2 are also known risk factors for male breast cancer (MBC). The role of other breast cancer genes in MBC is less
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4819e7805611ab5361165ecad3b1625
https://erepo.uef.fi/handle/123456789/5171
https://erepo.uef.fi/handle/123456789/5171
Autor:
Michailidou, K., Hall, P., Gonzalez-Neira, A., Ghoussaini, M., Dennis, J., Milne, R.L., Schmidt, M.K., Chang-Claude, J., Bojesen, S.E., Bolla, M.K., Wang, Q., Dicks, E., Lee, A., Turnbull, C., Rahman, N., Fletcher, O., Peto, J., Gibson, L., Silva, I.D., Nevanlinna, H., Muranen, T.A., Aittomaki, K., Blomqvist, C., Czene, K., Irwanto, A., Liu, J.J., Waisfisz, Q., Meijers-Heijboer, H., Adank, M., Luijt, R.B. van der, Hein, R., Dahmen, N., Beckman, L., Meindl, A., Schmutzler, R.K., Muller-Myhsok, B., Lichtner, P., Hopper, J.L., Southey, M.C., Makalic, E., Schmidt, D.F., Uitterlinden, A.G., Hofman, A., Hunter, D.J., Chanock, S.J., Vincent, D., Bacot, F., Tessier, D.C., Canisius, S., Wessels, L.F.A., Haiman, C.A., Shah, M., Luben, R., Brown, J., Luccarini, C., Schoof, N., Humphreys, K., Li, J.M., Nordestgaard, B.G., Nielsen, S.F., Flyger, H., Couch, F.J., Wang, X.S., Vachon, C., Stevens, K.N., Lambrechts, D., Moisse, M., Paridaens, R., Christiaens, M.R., Rudolph, A., Nickels, S., Flesch-Janys, D., Johnson, N., Aitken, Z., Aaltonen, K., Heikkinen, T., Broeks, A., Van't Veer, L.J., Schoot, C.E. van der, Guenel, P., Truong, T., Laurent-Puig, P., Menegaux, F., Marme, F., Schneeweiss, A., Sohn, C., Burwinke, B., Zamora, M.P., Perez, J.I.A., Pita, G., Alonso, M.R., Cox, A., Brock, I.W., Cross, S.S., Reed, M.W.R., Sawyer, E.J., Tomlinson, I., Kerin, M.J., Miller, N., Henderson, B.E., Schumacher, F., Marchand, L. le, Andrulis, I.L., Knight, J.A., Glendon, G., Mulligan, A.M., Lindblom, A., Margolin, S., Hooning, M.J., Hollestelle, A., Ouweland, A.M.W. van den, Jager, A., Bui, Q.M., Stone, J., Dite, G.S., Apicella, C., Tsimiklis, H., Giles, G.G., Severi, G., Baglietto, L., Fasching, P.A., Haeberle, L., Ekici, A.B., Beckmann, M.W., Brenner, H., Muller, H., Arndt, V., Stegmaier, C., Swerdlown, A., Ashworth, A., Orr, N., Jones, M., Figueroa, J., Lissowska, J., Brinton, L., Goldberg, M.S., Labreche, F., Dumont, M., Winqvist, R., Pylkas, K., Jukkola-Vuorinen, A., Grip, M., Brauch, H., Hamann, U., Bruning, T., Radice, P., Peterlongo, P., Manouldan, S., Bonanni, B., Devilee, P., Tollenaar, R.A.E.M., Seynaeve, C., Asperen, C.J. van, Jakubowska, A., Lubinski, J., Jaworska, K., Durda, K., Mannermaa, A., Kataja, V., Kosma, V.M., Hartikainen, J.M., Bogdanova, N.V., Antonenkova, N.N., Dork, T., Kristensen, V.N., Anton-Culver, H., Slager, S., Toland, A.E., Edge, S., Fostira, F., Kang, D., Yoo, K.Y., Noh, D.Y., Matsuo, K., Ito, H., Iwata, H., Sueta, A., Wu, A.H., Tseng, C.C., Berg, D. van den, Stram, D.O., Shu, X.O., Lu, W., Gao, Y.T., Cai, H., Teo, S.H., Yip, C.H., Phuah, S.Y., Cornes, B.K., Hartman, M., Miao, H., Lim, W.Y., Sng, J.H., Muir, K., Lophatananon, A., Stewart-Brown, S., Siriwanarangsan, P., Shen, C.Y., Hsiung, C.N., Wu, P.E., Ding, S.L., Sangrajrang, S., Gaborieau, V., Brennan, P., Mckay, J., Blot, W.J., Signorello, L.B., Cai, Q.Y., Zheng, W., Deming-Halverson, S., Shrubsole, M., Long, J.R., Simard, J., Garcia-Closas, M., Pharoah, P.D.P., Chenevix-Trench, G., Dunning, A.M., Benitez, J., Easton, D.F., Breast Ovarian Canc Susceptibility, Hereditary Breast Ovarian Canc Res, kConFab Investigators, Australian Ovarian Can Study Grp, GENICA Gene Environm Interaction B
Publikováno v:
Nature genetics, 45(4). Nature Publishing Group
Nature Genetics; Vol 45
Nature Genetics, 45(4), 353-361
Nature Genetics, 45(4), 353-361. Nature Publishing Group
Michailidou, K, Hall, P, Gonzalez-Neira, A, Ghoussaini, M, Dennis, J, Milne, R L, Schmidt, M K, Chang-Claude, J, Bojesen, S E, Bolla, M K, Wang, Q, Dicks, E, Lee, A, Turnbull, C, Rahman, N, Fletcher, O, Peto, J, Gibson, L, Silva, I D, Nevanlinna, H, Muranen, T A, Aittomaki, K, Blomqvist, C, Czene, K, Irwanto, A, Liu, J J, Waisfisz, Q, Meijers-Heijboer, H, Adank, M, van der Luijt, R B, Hein, R, Dahmen, N, Beckman, L, Meindl, A, Schmutzler, R K, Muller-Myhsok, B, Lichtner, P, Hopper, J L, Southey, M C, Makalic, E, Schmidt, D F, Uitterlinden, A G, Hofman, A, Hunter, D J, Chanock, S J, Vincent, D, Bacot, F, Tessier, D C, Canisius, S, Wessels, L F A, Haiman, C A, Shah, M, Luben, R, Brown, J C, Luccarini, C, Schoof, N, Humphreys, K, Li, J M, Nordestgaard, B G, Nielsen, S F, Flyger, H, Couch, F J, Wang, X S, Vachon, C, Stevens, K N, Lambrechts, D, Moisse, M, Paridaens, R, Christiaens, M R, Rudolph, A, Nickels, S, Flesch-Janys, D, Johnson, N, Aitken, Z, Aaltonen, K, Heikkinen, T, Broeks, A, van 't Veer, L J, van der Schoot, C E, Guenel, P, Truong, T, Laurent-Puig, P, Menegaux, F, Marme, F, Schneeweiss, A, Sohn, C, Burwinke, B, Zamora, M P, Perez, J I A, Pita, G, Alonso, M R, Cox, A, Brock, I W, Cross, S S, Reed, M W R, Sawyer, E J, Tomlinson, I, Kerin, M J, Miller, N, Benitez, J & Easton, D F 2013, ' Large-scale genotyping identifies 41 new loci associated with breast cancer risk ', Nature Genetics, vol. 45, no. 4, pp. 353-361 . https://doi.org/10.1038/ng.2563
Nature Genetics
Nature Genetics; Vol 45
Nature Genetics, 45(4), 353-361
Nature Genetics, 45(4), 353-361. Nature Publishing Group
Michailidou, K, Hall, P, Gonzalez-Neira, A, Ghoussaini, M, Dennis, J, Milne, R L, Schmidt, M K, Chang-Claude, J, Bojesen, S E, Bolla, M K, Wang, Q, Dicks, E, Lee, A, Turnbull, C, Rahman, N, Fletcher, O, Peto, J, Gibson, L, Silva, I D, Nevanlinna, H, Muranen, T A, Aittomaki, K, Blomqvist, C, Czene, K, Irwanto, A, Liu, J J, Waisfisz, Q, Meijers-Heijboer, H, Adank, M, van der Luijt, R B, Hein, R, Dahmen, N, Beckman, L, Meindl, A, Schmutzler, R K, Muller-Myhsok, B, Lichtner, P, Hopper, J L, Southey, M C, Makalic, E, Schmidt, D F, Uitterlinden, A G, Hofman, A, Hunter, D J, Chanock, S J, Vincent, D, Bacot, F, Tessier, D C, Canisius, S, Wessels, L F A, Haiman, C A, Shah, M, Luben, R, Brown, J C, Luccarini, C, Schoof, N, Humphreys, K, Li, J M, Nordestgaard, B G, Nielsen, S F, Flyger, H, Couch, F J, Wang, X S, Vachon, C, Stevens, K N, Lambrechts, D, Moisse, M, Paridaens, R, Christiaens, M R, Rudolph, A, Nickels, S, Flesch-Janys, D, Johnson, N, Aitken, Z, Aaltonen, K, Heikkinen, T, Broeks, A, van 't Veer, L J, van der Schoot, C E, Guenel, P, Truong, T, Laurent-Puig, P, Menegaux, F, Marme, F, Schneeweiss, A, Sohn, C, Burwinke, B, Zamora, M P, Perez, J I A, Pita, G, Alonso, M R, Cox, A, Brock, I W, Cross, S S, Reed, M W R, Sawyer, E J, Tomlinson, I, Kerin, M J, Miller, N, Benitez, J & Easton, D F 2013, ' Large-scale genotyping identifies 41 new loci associated with breast cancer risk ', Nature Genetics, vol. 45, no. 4, pp. 353-361 . https://doi.org/10.1038/ng.2563
Nature Genetics
Journal article Breast cancer is the most common cancer among women. Common variants at 27 loci have been identified as associated with susceptibility to breast cancer, and these account for ~9% of the familial risk of the disease. We report here a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e67ce99d85e1e04916e33425529f5e91
http://hdl.handle.net/10379/12885
http://hdl.handle.net/10379/12885
Autor:
Ana Luísa Correia, Ana Sofia Ribeiro, Fernando Schmitt, Marc Bracke, Bárbara Sousa, Raquel Seruca, Joana Paredes, André Albergaria
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Cell-cell adhesion is an elementary process in normal epithelial cellular architecture. Several studies have shown the role mediated by cadherins in this process, besides their role in the maintenance of cell polarity, differentiation and cell growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::678d05d177b8757189b519b779289408
https://hdl.handle.net/1822/67565
https://hdl.handle.net/1822/67565
Publikováno v:
Breast Cancer Research and Treatment
A mixed methods, community-based research study was conducted to understand how provider-level factors contribute to the African-American and white disparity in breast cancer mortality in a lower socioeconomic status area of North St. Louis. This stu
Autor:
Ian E. Krop, Andrea L. Richardson, Ines Vaz-Luis, Elizabeth S. Frank, Stuart G. Silverman, Kimberly E. Washington, Jessica Sohl, Joseph M. Fonte, Nan Lin, Erica L. Mayer, Beth Overmoyer, Eric P. Winer, Catherine A. Zeghibe
Publikováno v:
Breast Cancer Research and Treatment
e17574 Background: There is active debate concerning the ethics and risks of non-clinically indicated biopsies (bxs) in patients (pts) with cancer. In this analysis we examined our single institution experience regarding acceptance, safety, and succe
Autor:
Magda A Blaut, Thilo Dörk, Michael Bremer, Natalia Bogdanova, Evgeny N. Imyanitov, Hans Christiansen, Aglaya G. Iyevleva, Svetlana N. Abysheva, Anna P. Sokolenko, Margret Rave-Fränk
Publikováno v:
Breast Cancer Research and Treatment
Since germline mutations in the PALB2 (Partner and Localizer of BRCA2) gene have been identified as breast cancer (BC) susceptibility alleles, the geographical spread and risks associated with PALB2 mutations are subject of intense investigation. Pat
Autor:
Shirley W. Flatt, Cynthia A. Thomson, Vicky A. Newman, Ruth E. Patterson, Lisa A. Cadmus Bertram, Cheryl L. Rock, Nazmus Saquib, Wayne A. Bardwell, John P. Pierce, Loki Natarajan, Marcia L. Stefanick
Publikováno v:
Cancer Causes & Control
Cancer causes & control : CCC, vol 22, iss 3
Cancer causes & control : CCC, vol 22, iss 3
Objective Research suggests that physical activity is associated with improved breast cancer survival, yet no studies have examined the association between post-diagnosis changes in physical activity and breast cancer outcomes. The aim of this study