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pro vyhledávání: ''
Autor:
Nobuhide Higashino, Mari Nishio, Masaki Shimizu, Yoshihiro Kakeji, Masataka Fujikawa, Takayuki Kodama, Hiroki Sakamoto, Hiroshi Yokozaki, Kohei Tanigawa, Manabu Shigeoka, Yu-ichiro Koma
Publikováno v:
Laboratory Investigation; a Journal of Technical Methods and Pathology
Cancer-associated fibroblasts (CAFs) contribute to the progression of various cancers. Previously, we reported the significance of CAFs in esophageal squamous cell carcinoma (ESCC); however, the functions of CAFs in the ESCC microenvironment remain u
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Scientific Reports
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
The biological mechanisms involved in aseptic loosening include inflammation-associated and bone resorption-associated processes. Coordinated cellular actions result in biochemical imbalances with devastating consequences for the joint. Given that th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a18f50d25232d779a03a6ffd0ec8d2a
https://doi.org/10.1038/s41598-020-79813-x
https://doi.org/10.1038/s41598-020-79813-x
Autor:
A S Walker, Brian D. Marsden, T Peto, I Bell, Alison Howarth, Ruth Studley, E Y Jones, John N Newton, David I. Stuart, Emma Rourke, Koen B. Pouwels, Sarah Hoosdally, Philippa C Matthews, Jeremy Farrar, David W Eyre, Jia Wei, Nicole Stoesser, John Bell, Daniel Ayoubkhani, Ian Diamond, D Crook
Publikováno v:
Nature Microbiology
We report that in a cohort of 45,965 adults, who were receiving either the ChAdOx1 or the BNT162b2 SARS-CoV-2 vaccines, in those who had no prior infection with SARS-CoV-2, seroconversion rates and quantitative antibody levels after a single dose wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e1871384515e8b2b32c5b67cd6b1386
https://doi.org/10.1038/s41564-021-00947-3
https://doi.org/10.1038/s41564-021-00947-3
Autor:
Martina Schifferer, Ludovico Cantuti-Castelvetri, Susanne A. Schneider, Sabina Tahirovic, Andrew P. Lieberman, Jasmin König, Lina Dinkel, Silva Hećimović, Laura Sebastian Monasor, Tatiana Bremova-Ertl, Lea Vidatic, Alessio Colombo, Stephan A. Müller, Stefan F. Lichtenthaler, Michael Strupp, Mikael Simons
Publikováno v:
Nature communications
Nature Communications 12(1), 1158 (2021). doi:10.1038/s41467-021-21428-5
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Colombo, Alessio; Dinkel, Lina; Müller, Stephan A; Sebastian Monasor, Laura; Schifferer, Martina; Cantuti-Castelvetri, Ludovico; König, Jasmin; Vidatic, Lea; Bremova-Ertl, Tatiana; Lieberman, Andrew P; Hecimovic, Silva; Simons, Mikael; Lichtenthaler, Stefan F; Strupp, Michael; Schneider, Susanne A; Tahirovic, Sabina (2021). Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia. Nature Communications, 12(1), p. 1158. Springer Nature 10.1038/s41467-021-21428-5
Nature Communications 12(1), 1158 (2021). doi:10.1038/s41467-021-21428-5
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Colombo, Alessio; Dinkel, Lina; Müller, Stephan A; Sebastian Monasor, Laura; Schifferer, Martina; Cantuti-Castelvetri, Ludovico; König, Jasmin; Vidatic, Lea; Bremova-Ertl, Tatiana; Lieberman, Andrew P; Hecimovic, Silva; Simons, Mikael; Lichtenthaler, Stefan F; Strupp, Michael; Schneider, Susanne A; Tahirovic, Sabina (2021). Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia. Nature Communications, 12(1), p. 1158. Springer Nature 10.1038/s41467-021-21428-5
Niemann-Pick type C disease is a rare neurodegenerative disorder mainly caused by mutations in NPC1, resulting in abnormal late endosomal/lysosomal lipid storage. Although microgliosis is a prominent pathological feature, direct consequences of NPC1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::293f3dd22cdadfd9d9d515dc2698deab
http://fulir.irb.hr/6941/
http://fulir.irb.hr/6941/
Autor:
Ilkka Heikkinen, Ricardo D. Coletta, Tuula Salo, Jaana Hagström, Pentti Nieminen, Antti Mäkitie, Caj Haglund, Alhadi Almangush, Ibrahim O. Bello, Luiz Paulo Kowalski, Ilmo Leivo
Publikováno v:
Virchows Archiv
Stromal categorization has been used to classify many epithelial cancer types. We assessed the desmoplastic reaction and compared its significance with other stromal characteristics in early (cT1-2N0) oral tongue squamous cell carcinoma (OTSCC). In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7aea1c258b19d93e74afa2c0559bfa9
http://urn.fi/urn:nbn:fi-fe20201214100645
http://urn.fi/urn:nbn:fi-fe20201214100645
Autor:
Udo Kellner, Judith Martha Neumann, Hans Christoph Knobloch, Tibor Szarvas, Felix Bremmer, Ulrich Krafft, Péter Nyirády, Nils Neumann, Hanna Bednarz, Karsten Niehaus, Henning Reis
Publikováno v:
Laboratory Investigation; a Journal of Technical Methods and Pathology
Urachal adenocarcinomas (UrC) are rare but aggressive. Despite being of profound therapeutic relevance, UrC cannot be differentiated by histomorphology alone from other adenocarcinomas of differential diagnostic importance. As no reliable tissue-base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4996f963a1e1214db5edfd99163de2f9
https://pub.uni-bielefeld.de/record/2955244
https://pub.uni-bielefeld.de/record/2955244
Autor:
Marta G. Montero, Rocio Sotillo, Pablo Lujan, Andreas Hoffmann, Teresa Rubio, Maja Köhn, Martin Jechlinger, Judith Weyershaeuser
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Journal of Molecular Medicine (Berlin, Germany)
Universidad de Barcelona
Journal of Molecular Medicine (Berlin, Germany)
Expression of the phosphatase of regenerating liver-3 (PRL-3) is known to promote tumor growth in gastrointestinal adenocarcinomas, and the incidence of tumor formation upon inflammatory events correlates with PRL-3 levels in mouse models. These carc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed807464d3c3245931f59389ac0d27c
http://hdl.handle.net/2445/178674
http://hdl.handle.net/2445/178674
Autor:
Yuichi Sakamori, Naoki Nakajima, Toyohiro Hirai, Takahiro Tsuji, Akihiko Yoshizawa, Toshi Menju, Hiroaki Ozasa, Hitomi Ajimizu, Hiroshi Date, Hironori Yoshida, Yuto Yasuda, Tomoko Funazo, Masatoshi Yamazoe, Takashi Nomizo, Young Hak Kim
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 3, Pp 1-15 (2020)
Cell Death and Disease, Vol 11, Iss 3, Pp 1-15 (2020)
There have been few advances in the treatment of small-cell lung cancer (SCLC) because of the lack of targets. MCL1, a member of the anti-apoptotic BCL-2 family, may be a treatment target in several cancers, including SCLC. However, whether the expre
Autor:
Edurne Gallastegui, Josep Saura, Carla Domuro, Oriol Bachs, Mario Ezquerra, Carme Solà, María-José Martí, Leonardo Márquez-Kisinousky, Tony Valente, Guido Dentesano, Marco Straccia, Jonatan Martinez-Martin, Yaroslau Compta, Rubén Fernández-Santiago
Publikováno v:
Cell Death Differ
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
α-Synuclein is the main component of Lewy bodies, the intracellular protein aggregates representing the histological hallmark of Parkinson’s disease. Elevated α-synuclein levels and mutations in SNCA gene are associated with increased risk for Pa
Autor:
Sandra Boesmueller, Johannes Streicher, Lena Hirtler, Rainer Mittermayr, Roland Blumer, Angel M. Pastor, Daniel Bormann, Bernhard Gesslbauer
Publikováno v:
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
instname
The innervation of the long head of the biceps tendon (LHBT) is not sufficiently documented. This is a drawback since pathologies of the LHBT are a major source of shoulder pain. Thus, the study aimed to characterize structurally and molecularly nerv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a6641ab4ba4962ff2fa63b015be5490