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Publikováno v:
Journal of Human Genetics
Breast cancer is a heterogeneous disease that develops through a multistep process via the accumulation of genetic/epigenetic alterations in various cancer-related genes. Current treatment options for breast cancer patients include surgery, radiother
Autor:
Waleed S. Al Amri, William E. Hughes, James L. Thorne, Geoff Wells, Ian M. Carr, Brian V Hogan, Thomas A. Hughes, Fiona Langlands, Arindam Pramanik, Layla K. Younis, Stacey J. Jones, Sarah A. Harris, Eldo T. Verghese, Rebecca Millican-Slater, Nevine M.F. El Deeb, Mervat A. Hamza, Baek Kim, Noha Gwili
Publikováno v:
British Journal of Cancer
Background Breast cancer stem cells (BCSCs) are drivers of therapy-resistance, therefore are responsible for poor survival. Molecular signatures of BCSCs from primary cancers remain undefined. Here, we identify the consistent transcriptome of primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a64defdd7881cec05092b3963a5ac9
https://eprints.whiterose.ac.uk/174958/7/s41416-021-01484-w.pdf
https://eprints.whiterose.ac.uk/174958/7/s41416-021-01484-w.pdf
Autor:
Marta Vilalta, Adam J. Krieg, Caiyun G. Li, Eui Jung Moon, Amato J. Giaccia, Jen-Tsan Chi, Edward E. Graves, Jacob G. Kirkland, Stephano S. Mello, Anh N. Diep, Marjan Rafat, Yu Miao, Edward L. LaGory, Laura D. Attardi, Kaushik N. Thakkar, Laura Castellini, Ik Jae Lee
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications
Nature Communications
Hypoxia plays a critical role in tumor progression including invasion and metastasis. To determine critical genes regulated by hypoxia that promote invasion and metastasis, we screen fifty hypoxia inducible genes for their effects on invasion. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574b64acea8911667a49665037069c39
https://doi.org/10.1038/s41467-021-24631-6
https://doi.org/10.1038/s41467-021-24631-6
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
© The Author(s), under exclusive licence to Springer Nature B.V. 2021
Breast cancer is a heterogeneous disease, which is the most common malignancy in women. The incidence and mortality rates of breast cancer indicate that it is the leading cau
Breast cancer is a heterogeneous disease, which is the most common malignancy in women. The incidence and mortality rates of breast cancer indicate that it is the leading cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f8704585dfee30fde57fafbb3e3a01
https://hdl.handle.net/10451/47138
https://hdl.handle.net/10451/47138
Publikováno v:
Breast Cancer Research and Treatment
Purpose This systematic review examined educational training interventions for healthcare professionals (HCPs) discussing genetic testing and risk for hereditary breast cancer. There was a particular focus on the presence, and content, of communicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c95c00137135ccdad16368a0165e339f
http://sro.sussex.ac.uk/id/eprint/92115/1/Starkings_et_al-2020-Breast_Cancer_Research_and_Treatment.pdf
http://sro.sussex.ac.uk/id/eprint/92115/1/Starkings_et_al-2020-Breast_Cancer_Research_and_Treatment.pdf
Autor:
Shichina Kannambath, Joy Burchell, Natalie Woodman, Fabio Grundland Freile, Julie Owen, Ester Pfeifer, Sarah E Pinder, Ulla Mandel, Thomas Noll, Richard Beatson, Rosamond Nuamah, Joyce Taylor-Papadimitriou, Cheryl Gillett, Rosalind Graham, Ihssane Bouybayoune, Domenico Cozzetto
Publikováno v:
Communications Biology
Beatson, R, Graham, R, Grundland Freile, F, Cozzetto, D, Kannambath, S, Pfeifer, E, Woodman, N, Owen, J, Nuamah, R, Mandel, U, Pinder, S, Gillett, C, Noll, T, Bouybayoune, I, Taylor-Papadimitriou, J & Burchell, J M 2020, ' Cancer-associated hypersialylated MUC1 drives the differentiation of human monocytes into macrophages with a pathogenic phenotype ', Communications Biology, vol. 3, 644 . https://doi.org/10.1038/s42003-020-01359-5
Communications Biology, Vol 3, Iss 1, Pp 1-15 (2020)
Beatson, R, Graham, R, Grundland Freile, F, Cozzetto, D, Kannambath, S, Pfeifer, E, Woodman, N, Owen, J, Nuamah, R, Mandel, U, Pinder, S, Gillett, C, Noll, T, Bouybayoune, I, Taylor-Papadimitriou, J & Burchell, J M 2020, ' Cancer-associated hypersialylated MUC1 drives the differentiation of human monocytes into macrophages with a pathogenic phenotype ', Communications Biology, vol. 3, no. 1, 644 . https://doi.org/10.1038/s42003-020-01359-5
Beatson, R, Graham, R, Grundland Freile, F, Cozzetto, D, Kannambath, S, Pfeifer, E, Woodman, N, Owen, J, Nuamah, R, Mandel, U, Pinder, S, Gillett, C, Noll, T, Bouybayoune, I, Taylor-Papadimitriou, J & Burchell, J M 2020, ' Cancer-associated hypersialylated MUC1 drives the differentiation of human monocytes into macrophages with a pathogenic phenotype ', Communications Biology, vol. 3, 644 . https://doi.org/10.1038/s42003-020-01359-5
Communications Biology, Vol 3, Iss 1, Pp 1-15 (2020)
Beatson, R, Graham, R, Grundland Freile, F, Cozzetto, D, Kannambath, S, Pfeifer, E, Woodman, N, Owen, J, Nuamah, R, Mandel, U, Pinder, S, Gillett, C, Noll, T, Bouybayoune, I, Taylor-Papadimitriou, J & Burchell, J M 2020, ' Cancer-associated hypersialylated MUC1 drives the differentiation of human monocytes into macrophages with a pathogenic phenotype ', Communications Biology, vol. 3, no. 1, 644 . https://doi.org/10.1038/s42003-020-01359-5
The tumour microenvironment plays a crucial role in the growth and progression of cancer, and the presence of tumour-associated macrophages (TAMs) is associated with poor prognosis. Recent studies have demonstrated that TAMs display transcriptomic, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee333a13b7e86e9384b8c9eaed7802b
https://pub.uni-bielefeld.de/record/2948753
https://pub.uni-bielefeld.de/record/2948753
Autor:
Elise Klæstad, Signe Opdahl, Monica J. Engstrøm, Elisabeth Wik, Borgny Ytterhus, Anna M. Bofin, Marit Valla
Publikováno v:
Breast Cancer Research and Treatment
Purpose MRPS23 is recognized as a driver of proliferation in luminal breast cancer. The aims of the present study were to describe MRPS23 copy number change in breast cancer, and to assess associations between MRPS23 copy number change and molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49102c4df90ac263d4c308ee2094e138
https://hdl.handle.net/11250/2672584
https://hdl.handle.net/11250/2672584
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
© The Japanese Breast Cancer Society 2020
Circular RNAs are a large group of non-coding RNAs with a closed-loop structure. circRNAs play significant roles in many biological processes as miRNA sponges, regulators for gene transcription, combini
Circular RNAs are a large group of non-coding RNAs with a closed-loop structure. circRNAs play significant roles in many biological processes as miRNA sponges, regulators for gene transcription, combini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::801707b328990305344fcc66688ff574
https://hdl.handle.net/10451/49737
https://hdl.handle.net/10451/49737
Autor:
Jon Emery, Cristina Renzi, Georgios Lyratzopoulos, Greg Rubin, Willie Hamilton, Niek J. de Wit, Fiona M Walter, Hardeep Singh, Richard D Neal, Aradhna Kaushal, Bernard Rachet
Publikováno v:
Nature Reviews Clinical Oncology, 16(12), 746. Nature Publishing Group
An earlier diagnosis is a key strategy for improving the outcomes of patients with cancer. However, achieving this goal can be challenging, particularly for the growing number of people with one or more chronic conditions (comorbidity/multimorbidity)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7eae9ffd1b6337625278ba256d6a47
Autor:
Masako Sato, Hidetoshi Kawaguchi, Satoshi Morita, Makiko Mizutani, Yoshie Hasegawa, Ken-ichi Watanabe, Yasuaki Sagara, Fumikata Hara, Takashi Morimoto, Takahiro Nakayama, Norikazu Masuda, Mitsuya Itoh, Shoichiro Ohtani, Nobuki Matsunami, Kenji Higaki, Masato Takahashi, Tetsuhiro Yoshinami
Publikováno v:
Breast Cancer (Tokyo, Japan)
Background This study aimed to investigate whether schedule modification is safe and effective in patients intolerant to the standard eribulin dose and schedule. Methods Patients with metastatic breast cancer (MBC) treated with both anthracycline and