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Autor:
Ring, A., Battisti, N.M.L., Reed, M.W.R., Herbert, E., Morgan, J.L., Bradburn, M., Walters, S.J., Collins, K.A., Ward, S.E., Holmes, G.R., Burton, Maria, Lifford, K., Edwards, A., Robinson, T.G., Martin, C., Chater, T., Pemberton, K.J., Brennan, A., Cheung, K.L., Todd, A., Audisio, R.A., Wright, J., Simcock, R., Green, T., Revell, D., Gath, J., Horgan, K., Holcombe, C., Winter, M.C., Naik, J., Parmeshwar, R., Gosney, M.A., Hatton, M.Q., Thompson, A.M., Wyld, L., Collins, K., Ward, S., Holmes, G., Morgan, J., Walters, S., Burton, M., Brain, K., Robinson, T., Pemberton, K., Shrestha, A., Nettleship, A., Richards, P., Harder, H., Audisio, R., Murray, C., Thomson, A.M., Gosney, M., Hatton, M., Armitage, F., Patnick, J., Revill, D., Winter, M.
Publikováno v:
British Journal of Cancer
Background Chemotherapy improves outcomes for high risk early breast cancer (EBC) patients but is infrequently offered to older individuals. This study determined if there are fit older patients with high-risk disease who may benefit from chemotherap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed056944ecd27827ab3bd963813fe40
http://sro.sussex.ac.uk/id/eprint/101218/1/s41416-021-01388-9.pdf
http://sro.sussex.ac.uk/id/eprint/101218/1/s41416-021-01388-9.pdf
Autor:
Adam P. Cribbs, Yongjing Guo, Sundeept Bhalara, Bernard Gregory, Lih-Ling Lin, Marc Feldmann, Attila A. Seyhan, Yizheng Li, Ying Zhang, Christine Loreth, Lynn M. Williams, Peter C. Taylor, Fionula M. Brennan
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
We profiled gene expression signatures to distinguish rheumatoid arthritis (RA) from non-inflammatory arthralgia (NIA), self-limiting arthritis (SLA), and undifferentiated arthritis (UA) as compared to healthy controls as novel potential biomarkers f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24bccac40f02ddb5c763c49b32feaddb
https://doi.org/10.1038/s41598-020-63757-3
https://doi.org/10.1038/s41598-020-63757-3
Autor:
Munir Pirmohamed, Sandra Loaiza, Richard E. Clark, Ana E. Rodríguez-Vicente, Gemma Austin, Andrea Davies, Letizia Foroni
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific reports
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific reports
Digital.CSIC. Repositorio Institucional del CSIC
instname
Tyrosine kinase inhibitors (TKIs), the treatment of choice for chronic myeloid leukaemia (CML), can cause lower gastrointestinal (GI) toxicity which is manifested as diarrhoea. The mechanisms are not fully understood. The enteroendocrine signalling c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d921e866cc3711027543ac4d7a44d09
http://hdl.handle.net/10261/222988
http://hdl.handle.net/10261/222988
Autor:
Antti Tanskanen, Anna-Maija Tolppanen, Janne Hukkanen, Sirpa Hartikainen, Marjaana Koponen, Jari Tiihonen, Heidi Taipale, Heikki Kröger, Jaana Rysä
Publikováno v:
Osteoporosis International
Summary We investigated the association between thiazide use and the risk of low-energy fractures among community dwellers with Alzheimer’s disease. Longer use was associated with a decreased risk of low-energy fractures. This study extends the pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f427dbf204e03a901ff7426b6ed24a39
http://urn.fi/urn:nbn:fi-fe2019070122413
http://urn.fi/urn:nbn:fi-fe2019070122413
Publikováno v:
European Journal of Clinical Microbiology & Infectious Diseases
Reports on real-world experience on efficacy of bezlotoxumab (BEZ) has been lacking thus far. We retrospectively studied the efficacy and safety of BEZ in preventing the recurrence of Clostridium difficile infection (CDI) in five university hospitals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c4e16f39966f375dfbec8bf1b63798
http://urn.fi/urn:nbn:fi-fe202003097628
http://urn.fi/urn:nbn:fi-fe202003097628
Autor:
Solis-Hernandez, Mª Pilar, Fernandez del Valle, Ana, Carmona-Bayonas, Alberto, García-Carbonero, Rocío, Custodio, Ana, Benavent, Marta, Alonso-Gordoa, Teresa, Nuñez-Valdovino, Bárbara, Sanchez Canovas, Manuel, Matos, Ignacio, Alonso, Vicente, Lopez, Carlos, Viudez, Antonio, Izquierdo, Marta, Calvo-Temprano, David, Grande, Enrique, Capdevila Castillón, Jaume, Jimenez-Fonseca, Paula, Universitat Autònoma de Barcelona, Vall d'Hebron Institut d'Oncologia
Publikováno v:
British Journal of Cancer
Digital.CSIC. Repositorio Institucional del CSIC
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Digital.CSIC. Repositorio Institucional del CSIC
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
[Background] The purpose of our study was to analyse the usefulness of Choi criteria versus RECIST in patients with pancreatic neuroendocrine tumours (PanNETs) treated with sunitinib. [Method] A multicentre, prospective study was conducted in 10 Span
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Supra inguinal fascia iliaca compartment block (FICB) is increasingly used in elderly patients with hip fractures. However, the minimum effective volume of local anesthetics required for ultrasound-guided supra-inguinal FICB has not been determined.
Autor:
Kazushige Uchida, Terumi Kamisawa, Shoko Matsui, Seiji Nakamura, Hajime Yoshifuji, Tadashi Yoshino, Shintaro Hirata, Mitsuhiro Kawano, Yasuharu Sato, Tsutomu Chiba, Hiroki Takahashi, Mirei Shirakashi, Kazunori Yamada, Tsuneyo Mimori, Kazuichi Okazaki, Tetsuya Ito, Motoko Shibata, Hiroto Tsuboi, Masafumi Moriyama, Yuzo Kodama, Takayuki Sumida, Yoshiya Tanaka, Hiroshi Goto, Motohisa Yamamoto, Shigeyuki Kawa
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Scientific Reports
Scientific Reports
Glucocorticoids (GC) are effective for treating IgG4-related disease (IgG4-RD); however, relapse is often observed. We conducted a retrospective multicentre study to investigate risk factors in GC regimens associated with relapses of IgG4-RD. Data on
Autor:
Mariko Kano, Ryo Mukai, Masashi Ogasawara, Taku Sato, Hirokuni Kitamei, Ryo Yamada, Tomohiro Iida, Kazunori Miyata, Fumi Gomi, Akihiro Ohira, Hideki Koizumi, Masahiro Miyake, Hidetaka Matsumoto, Hiroyuki Iijima, Yasushi Kataoka, Takuya Awata, Kenji Yamashiro, Kanji Takahashi, Nagahisa Yoshimura, Kaori Sayanagi, Wataru Matsumiya, Isao Nakata, Naoshi Kondo, Akira Negi, Xue Tan, Taiichi Hikichi, Chikako Hara, Ryo Obata, Akio Oishi, Shoji Kishi, Masayuki Ohnaka, Yoichi Sakurada, Munemitsu Yoshikawa, Seigo Yoneyama, Takashi Tsuchihashi, Takeshi Iwata, Shigeru Honda, Yoshimi Nagai, Keiko Azuma, Sho Kabasawa, Kazuhiro Ueyama, Satoshi Inoue, Masaaki Saito, Akiko Miki, Yasuo Yanagi, Tetsuju Sekiryu, Hidenori Takahashi, Yasurou Koyama, Sotaro Ooto, Hiroshi Tamura, Kuniko Horie-Inoue, Hiroaki Bessho, Shin Yoneya, Fumihiko Matsuda, Keisuke Mori, Akitaka Tsujikawa, Akira Obana, Wataru Kikushima
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
We conducted a genome-wide association study (GWAS) on the outcome of anti-VEGF treatment for exudative age-related macular degeneration (AMD) in a prospective cohort. Four hundred and sixty-one treatment-naïve AMD patients were recruited at 13 clin
Autor:
Yasuo Ohashi, Tatsuya Ioka, Hiroyuki Maguchi, Yasuo Hamamoto, Takuji Okusaka, H. Ueno, Hirofumi Fujii, Hiroyuki Miyakawa, Taroh Satoh, A. Sato, Ann-Lii Cheng, Takamichi Ito, J. Furuse, S. Matsumoto, Kazuhiro Mizumoto, S. Ohkawa, Shinichi Egawa, Kenji Yamao, S. Nakamori, Takuhiro Yamaguchi, Narikazu Boku, Akihiro Funakoshi, Takashi Hatori, Masao Tanaka, Jen-Shi Chen
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Purpose The GEST study showed non-inferiority of S-1 but not superiority of gemcitabine plus S-1 (GS) to gemcitabine alone for overall survival with the data by the cut-off date of 31st July in 2010 for chemo-naïve patients with advanced pancreatic