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Autor:
Shinichi Sakuramoto, Hitoshi Katai, Mitsuru Sasako, Hiroshi Imamura, Koji Kitada, Masanori Terashima, Atsushi Ochiai, Issei Kurahashi, Wataru Ichikawa, Takeshi Sano
Publikováno v:
Gastric Cancer
Background Exploratory biomarker analysis was conducted to identify factors related to the outcomes of patients with stage II/III gastric cancer using data from the Adjuvant Chemotherapy Trial of S-1 for Gastric Cancer, which was a randomized control
Autor:
Daisuke Gomi, Narikazu Boku, Yusuke Tanigawara, Tsunehiro Takahashi, Hirofumi Kawakubo, Hiroya Takeuchi, Kenzo Soejima, Yuko Kitagawa, Kazunari Tateishi, Takashi Ichiyama, Takuro Mizukami, Yasuo Hamamoto, Chiyo K. Imamura, Eisuke Booka
Publikováno v:
Gastric Cancer
Background S-1 is an oral anticancer drug, containing tegafur (a prodrug of 5-fluorouracil, 5-FU), 5-chloro-2,4-dihydroxypyridine, and potassium oxonate. As renal dysfunction is known to increase exposure of 5-FU following S-1 administration, the inc