Zobrazeno 31 - 40
of 211
pro vyhledávání: ''
Autor:
Gwen S. Stinnett, Guoxiang Luo, Verginia C. Cuzon Carlson, Armando G. Salinas, Audrey F. Seasholtz, Yolanda Mateo, David M. Lovinger, Kathleen A. Grant
Publikováno v:
Neuropsychopharmacology
The dorsal striatum (DS) is implicated in behavioral and neural processes including action control and reinforcement. Alcohol alters these processes in rodents, and it is believed that the development of alcohol use disorder involves changes in DS do
Publikováno v:
PharmacoEconomics Open
Objective The aim of this study was to investigate the cost effectiveness of nivolumab versus docetaxel in previously treated, advanced non–small-cell lung cancer (NSCLC) in England and assess how conditional reimbursement within the Cancer Drugs F
Publikováno v:
Drug Safety
Introduction Drug safety studies regarding comparative risk of different opioid compounds are important as providers and regulatory agencies in the United States continue to balance pain management with an ongoing opioid epidemic. Objective The aim o
Autor:
Ryutaro Shimamura, Debra J. Tompson, Annette S. Gross, Hirofumi Ogura, Takashi Nagakubo, Nicola Scott, Edward P. Cannons, Hiroko Ino, Atsushi Nakano, Michalis Kostapanos, Carwyn Davies, Marcy Powell, Harue Igarashi
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics
Funder: GlaxoSmithKline; doi: http://dx.doi.org/10.13039/100004330
BACKGROUND AND OBJECTIVES: GSK2982772 is an oral small-molecule RIPK1 inhibitor with potential therapeutic efficacy in immune-mediated inflammatory diseases (IMIDs). An inter-eth
BACKGROUND AND OBJECTIVES: GSK2982772 is an oral small-molecule RIPK1 inhibitor with potential therapeutic efficacy in immune-mediated inflammatory diseases (IMIDs). An inter-eth
Publikováno v:
Drug Safety
Introduction and Objective Intravenous iron preparations rapidly correct iron deficiency anemia, with the notable drug class effect of rare, yet potentially life-threatening, administration-related hypersensitivity or anaphylactic reactions. The obje
Publikováno v:
PharmacoEconomics Open
Background While much is known about the cost of community-acquired pneumonia (CAP) during the acute phase of illness, little is known about the potential attributable cost of CAP thereafter. Objective The aim of this study was to assess long-term at
Publikováno v:
Inflammation Research
Objective and design This systematic review aims to establish the role of CD8 + T lymphocytes in COPD. Methods Forty-eight papers published in the last 15 years were identified for inclusion. Results CD8 + T-cells are increased in the lungs of patien
Publikováno v:
Current Pharmacology Reports
Purpose of Review Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is identified from Wuhan, China, and has spread almost worldwide. Recently, the newly identified SARS-CoV-2 has been confirmed to kill millions of people worldwide and is
Autor:
Yijuan Li, Wen Tang, Yuxin Pei, Yujian Liang, Xueqiong Huang, Lingling Xu, Yu Li, Xiaoyun Jiang
Publikováno v:
International Journal of Clinical Pharmacy
Background The recommended dose of rasburicase is quite expensive, thus limiting its use. Whether a lower dose of rasburicase would be equally effective for critically ill children, who often have more complicated situations and a higher risk of hosp
Autor:
Xiaohui Wang, Karthik Venkatakrishnan, Elliot Offman, Michael J. Hanley, Neeraj Gupta, David Kerstein, Marita Prohn, Narayana I. Narasimhan
Publikováno v:
Clinical Pharmacokinetics
Background and objectives Brigatinib is an oral tyrosine kinase inhibitor approved in multiple countries for the treatment of patients with anaplastic lymphoma kinase-positive metastatic non-small cell lung cancer who have progressed on or are intole