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Publikováno v:
J Diabetes Metab Disord
PURPOSE: Phytochemicals of ethno medicines are being developed as effective drugs with minimum or no toxic side effects. Dhanwantaram Kashayam (DK) is a polyherbal formulation used as a potent general health tonic and is found to have antioxidant act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb546a3813f74f0c31a299f1224c1723
https://europepmc.org/articles/PMC7843830/
https://europepmc.org/articles/PMC7843830/
Autor:
Sachin Patel, Farhana Yasmin
Publikováno v:
Neuropsychopharmacology
Even a single 2-hour episode of immobilization stress is known to trigger anxiety-like behavior and increase spine-density in the basolateral amygdala (BLA) of rats 10 days later. This delayed build-up of morphological and behavioral effects offers a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ab550084c37ff900a00d1a049f4ca3b
https://europepmc.org/articles/PMC7784983/
https://europepmc.org/articles/PMC7784983/
Autor:
Nikolas J. Onufrak, Kevin L. Winthrop, David E. Griffith, Jakko van Ingen, Dayton W. Yuen, Christopher M. Rubino, Kevin C. Mange, Sujata M. Bhavnani
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics
Use of parenteral amikacin to treat refractory nontuberculous mycobacterial (NTM) lung disease is limited by systemic toxicity. A population pharmacokinetic model was developed using data pooled from two randomized trials to evaluate the pharmacokine
Autor:
Xiaoduo He, Tianqi Yao, Ming Song, Mo Zhang, Yongjuan Fu, Sijie Li, Shengli Li, Jian Chen, Di Wu, Xunming Ji, Longfei Wu, Mitchell Huber, Yuchuan Ding, Chuanjie Wu, Yongbiao Zhang
Publikováno v:
Neurotherapeutics
Early reperfusion is increasingly prioritized in ischemic stroke care, but outcomes remain suboptimal. Therefore, there is an urgent need to find neuroprotective approaches that can be combined with reperfusion to maximize efficacy. Here, the neuropr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee3595a502b505d0043632a26b4cfef
https://europepmc.org/articles/PMC7851312/
https://europepmc.org/articles/PMC7851312/
Publikováno v:
J Diabetes Metab Disord
PURPOSE: Diabetes mellitus is a complex metabolic disorder characterized by hyperglycemia occurring as a result of dysregulation and balance of various metabolic pathways. In recent years, circadian misalignment (due to altered sleep/wake, feeding/fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::441208ae7ba9d41fb96f70416787b3b7
https://europepmc.org/articles/PMC7843808/
https://europepmc.org/articles/PMC7843808/
Autor:
Cherise Chin Fatt, Katharina Kircanski, Argyris Stringaris, Abu Minhajuddin, Ellen Leibenluft, Madhukar H. Trivedi, Manish K. Jha
Publikováno v:
Neuropsychopharmacology
Irritability in pediatric samples is associated with higher rates of subsequent suicide-related outcomes. No study, to date, has evaluated the longitudinal association between irritability and suicidal ideation (SI) in adults with major depressive di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa7f1fd0d149341ea7335de1c188aedd
https://europepmc.org/articles/PMC7784964/
https://europepmc.org/articles/PMC7784964/
Autor:
Olukemi Adetutu Osukoya, Abidemi Paul Kappo, Babatunji Emmanuel Oyinloye, Precious Eseose Agboinghale, Basiru Olaitan Ajiboye, Lisa Ilobekemen Ekakitie, Oluwafemi Adeleke Ojo
Publikováno v:
J Diabetes Metab Disord
BACKGROUND: Gongronema latifolium leaf is used traditionally to treat diabetes and other diseases. The present study aimed to provide the modulatory effect of G. latifolium on hyperglycemia, inhibitory effect of redox imbalance and inflammation in al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7da670620ee8ed3cefbfc2a614d911b
https://europepmc.org/articles/PMC7270381/
https://europepmc.org/articles/PMC7270381/
Autor:
Dara M. Cannon, Laurena Holleran, Giulia Tronchin, Colm McDonald, Theophilus N. Akudjedu, Brian Hallahan, Mohamed Ahmed
Publikováno v:
Neuropsychopharmacology
74th Annual Meeting of the Society of Biological Psychiatry
74th Annual Meeting of the Society of Biological Psychiatry
The association of antipsychotic medication with abnormal brain morphometry in schizophrenia remains uncertain. This study investigated subcortical morphometric changes 6 months after switching treatment to clozapine in patients with treatment-resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c864e9b5f3d046875432048ff518054
https://europepmc.org/articles/PMC7298040/
https://europepmc.org/articles/PMC7298040/
Publikováno v:
Neuropsychopharmacology
The specific GluN2B antagonist rislenemdaz (Ris; a.k.a. MK-0657 and CERC-301) is in phase II clinical trial as an antidepressive drug, but the working mechanism for its antidepressant effects is not clearly understood. Given the important role of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ea70c2d17f1e4894ffb256e9073d4f
https://europepmc.org/articles/PMC7419533/
https://europepmc.org/articles/PMC7419533/
Autor:
Tracy L. Bale, Scott M. Thompson, Victoria E. Meadows, Anthony B. Cole, Kathleen E. Morrison, Patrick J. Kane
Publikováno v:
Neuropsychopharmacology
Women who have experienced adverse childhood events (ACEs) around puberty are at the greatest risk for neuropsychiatric disorders across the lifespan. This population is exceptionally vulnerable to neuropsychiatric disease presentation during the hor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad7abcbdf31f40a32b17f22cc9b987b
https://europepmc.org/articles/PMC7297802/
https://europepmc.org/articles/PMC7297802/