Zobrazeno 1 - 10
of 85
pro vyhledávání: ''
Autor:
David E. Meza-Sánchez, Miriam Pescador-Rojas, Víctor Adrián Sosa-Hernández, Víctor A. Sosa-Hernandez, Mariana Cañez-Hernández, Alfredo Pérez-Fragoso, Sandra Romero-Ramírez, Jiram Torres-Ruiz, Rodrigo Cervantes-Díaz, José L. Maravillas-Montero, Diana Gómez-Martín, José C. Páez-Franco
Publikováno v:
Inflammation Research
Objectives The role of B cells in COVID‐19, beyond the production of specific antibodies against SARS-CoV-2, is still not well understood. Here, we describe the novel landscape of circulating double-negative (DN) CD27− IgD− B cells in COVID‐1
Autor:
Mireia Martín-Satué, Marçal Pastor-Anglada, Loreto Boix, Clara Boces-Pascual, Aida Mata-Ventosa, Meritxell Gironella, Sandra Pérez-Torras
Publikováno v:
Cellular and Molecular Life Sciences
Dipòsit Digital de la UB
Universidad de Barcelona
Dipòsit Digital de la UB
Universidad de Barcelona
Graphic abstract High-affinity uptake of natural nucleosides as well as nucleoside derivatives used in anticancer therapies is mediated by human concentrative nucleoside transporters (hCNTs). hCNT1, the hCNT family member that specifically transports
Publikováno v:
Drug Safety
Introduction The safety profile of remdesivir, conditionally approved for COVID-19, was limited at its 2020 introduction. Adverse drug reactions (ADRs) for medicines are collected in VigiBase, the WHO Global Database of Individual Case Safety Reports
Publikováno v:
Pharmacological Reports
Background Intense statin therapy was found to impair testosterone production in men. Metformin administered to subjects with hypergonadotropic hypogonadism decreased gonadotropin production. The current study was aimed at investigating whether metfo
Autor:
Diana Santiago, Juan Guzmán, Julio Sandoval, Zaira Torres, Héctor González-Pacheco, Claudia Tavera-Alonso, Karen Audelo, Luis M. Amezcua-Guerra, Julieta González-Flores, Carlos García-Ávila, Francisco M. Baranda-Tovar
Publikováno v:
Inflammation Research
Objective To investigate whether a simplified inflammation-based risk scoring system comprising three readily available biomarkers (albumin, C-reactive protein, and leukocytes) may predict major adverse outcomes in patients with COVID-19. Methods Upo
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics
Background and Objective Clinical evidence suggests no clinically relevant pharmacokinetic interactions between indacaterol (IND), glycopyrronium (GLY) and mometasone furoate (MF). A population pharmacokinetic (popPK) analysis was conducted to identi
Autor:
John W. Day, Lisa Meng, Jean K. Mah, Bettina M. Cockroft, Andrew A. Wolff, Jenny Wei, Angela Genge, Anne M. Connolly, Ali Habib, Craig Campbell, Perry B. Shieh, Jeffrey Statland, Maryam Oskoui, Tina Duong, Carolina Tesi-Rocha, Basil T. Darras, Nicholas E. Johnson, Nancy L. Kuntz, Fady I. Malik, Stacy A. Rudnicki, Jinsy A. Andrews, Kevin Felice
Publikováno v:
Neurotherapeutics
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, vol 18, iss 2
Paediatrics Publications
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, vol 18, iss 2
Paediatrics Publications
This phase 2, double-blind, placebo-controlled, hypothesis-generating study evaluated the effects of oral reldesemtiv, a fast skeletal muscle troponin activator, in patients with spinal muscular atrophy (SMA). Patients ≥ 12 years of age with type I
Autor:
Matteo Respino, George S. Alexopoulos, Matthew J. Hoptman, Faith M. Gunning, Lindsay W. Victoria, Lila Abreu, Lauren Oberlin
Publikováno v:
Neuropsychopharmacology
Neuroimaging features of small vessel disease (SVD) are highly prevalent in older adulthood and associated with significant variability in clinical symptoms, yet the factors predicting these symptom disparities are poorly understood. We employed a no
Autor:
Zhe Cheng, Xiaokun Geng, Fenghai Li, Mohammed A Hussain, Marc Fisher, Gary Rajah, David Dornbos, Jie Gao, Yanna Tong, Huishan Du, Linlin Ma, Yuchuan Ding
Publikováno v:
Neurotherapeutics
Adjuvant neuroprotective therapies for acute ischemic stroke (AIS) have demonstrated benefit in animal studies, albeit without human translation. We investigated the safety and efficacy of high-flow normobaric oxygen (NBO) after endovascular recanali
Autor:
Rudiger Kaspera, Gernot K Klein, Begona Barroso-Fernandez, Virginie Kerbusch, Dorien Groenendaal-van de Meent, Martin den Adel, Piergiorgio Galletti
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics
Background and Objectives Roxadustat is an orally active hypoxia-inducible factor prolyl hydroxylase inhibitor for anemia in chronic kidney disease. The pharmacokinetics, metabolic profile, and pharmacodynamics of roxadustat were investigated in subj