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Publikováno v:
Pharmacological Reports
Background Intense statin therapy was found to impair testosterone production in men. Metformin administered to subjects with hypergonadotropic hypogonadism decreased gonadotropin production. The current study was aimed at investigating whether metfo
Autor:
Diana Santiago, Juan Guzmán, Julio Sandoval, Zaira Torres, Héctor González-Pacheco, Claudia Tavera-Alonso, Karen Audelo, Luis M. Amezcua-Guerra, Julieta González-Flores, Carlos García-Ávila, Francisco M. Baranda-Tovar
Publikováno v:
Inflammation Research
Objective To investigate whether a simplified inflammation-based risk scoring system comprising three readily available biomarkers (albumin, C-reactive protein, and leukocytes) may predict major adverse outcomes in patients with COVID-19. Methods Upo
Autor:
Elizabeth D. Moyer, Michael C. Powanda
Publikováno v:
Inflammopharmacology
There is an array of plasma protein alterations that occur in a wide variety of species, including humans in response to trauma, inflammation and infections, seemingly irrespective of etiologic agent. In numerous species, these plasma proteins are pa
Publikováno v:
Inflammation Research
Background The aim of this review is to explore whether patients with autoimmune diseases (AIDs) were at high risk of infection during the COVID-19 epidemic and how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic affected immune
Publikováno v:
Inflammation Research
Objective and design This systematic review aims to establish the role of CD8 + T lymphocytes in COPD. Methods Forty-eight papers published in the last 15 years were identified for inclusion. Results CD8 + T-cells are increased in the lungs of patien
Publikováno v:
Current Pharmacology Reports
Purpose of Review Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is identified from Wuhan, China, and has spread almost worldwide. Recently, the newly identified SARS-CoV-2 has been confirmed to kill millions of people worldwide and is
Publikováno v:
Pharmacological Reports
Background Women with polycystic ovary syndrome (PCOS) are characterized by increased cardiometabolic risk. The aim of the current study was to compare the impact of atorvastatin on plasma levels of cardiometabolic risk factors between men whose sist
Autor:
Emmanuel Ampofo, Eloisa Aparecida Vilas-Boas, Angelo Rafael Carpinelli, Noémie Karabacz, Maíra Melo Rezende Valle, Bruce A. Morgan, Gabriela Nunes Marsiglio-Librais, Leticia Prates Roma, Lisa Nalbach
Publikováno v:
Pharmacological Reports
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Background Free fatty acids (FFAs) are known for their dual effects on insulin secretion and pancreatic β-cell survival. Short-term exposure to FFAs, such as palmitate, increases insulin secretion. On the contrary, long-term exposure to saturated FF
Autor:
Sophie Beale, Marty Chaplin, Joanne McEntee, Rachel Houten, Yenal Dundar, Isabel Syndikus, Nigel Fleeman, Angela Stainthorpe, Angela Boland
Publikováno v:
PharmacoEconomics Open
PharmacoEconomics-open
PharmacoEconomics-open
As part of the single technology appraisal process, the National Institute for Health and Care Excellence invited Takeda UK Ltd to submit clinical- and cost-effectiveness evidence for brentuximab vedotin (BV) for treating relapsed or refractory CD30-
Autor:
Jie Chen, Wen Ouyang, Yaying Song, Zhongcong Xie, Xue-Qin Wang, Jianbin Tong, Yuan Le, Shuibing Zhang
Publikováno v:
Neurotherapeutics
Post-sepsis cognitive impairment is one of the major sequelae in sepsis survivors. Its prevention remains clinically challenging. Here we tested the effects and underlying mechanisms of exogenous β-hydroxybutyrate (BHB) on post-sepsis cognitive impa