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Publikováno v:
AMB Express
AMB Express, Vol 11, Iss 1, Pp 1-11 (2021)
AMB Express, Vol 11, Iss 1, Pp 1-11 (2021)
The present study aimed at isolation of endophytic basidiomycetous fungi and evaluation of their in-vitro and in-vivo antidiabetic potential. Preliminary screening for in-vitro activity was carried out using α-glucosidase inhibition assay. An endoph
Autor:
Debojyoti Moulick, Anupom Borah, Shuvasish Choudhury, Muhammed Khairujjaman Mazumder, Purbajyoti Saikia
Publikováno v:
In Silico Pharmacology
Severe Acute Respiratory Syndrome coronavirus (SARS-CoV), Middle East Respiratory Syndrome coronavirus (MERS-CoV) and the novel SARS-CoV-2 evade the host innate immunity, and subsequently the adaptive immune response, employing one protease called Pa
Autor:
Raquel M. Schears, Kevin M Takakuwa
Publikováno v:
International Journal of Emergency Medicine
International Journal of Emergency Medicine, Vol 14, Iss 1, Pp 1-18 (2021)
International Journal of Emergency Medicine, Vol 14, Iss 1, Pp 1-18 (2021)
BackgroundCannabis is the most prevalent illegal drug used and the second most common cause of ED drug-related complaints in the USA. Recently, newer more potent strains, concentrated THC products, and consumption methods have become available.Object
Publikováno v:
Clinical Phytoscience
Clinical Phytoscience, Vol 7, Iss 1, Pp 1-9 (2021)
Clinical Phytoscience, Vol 7, Iss 1, Pp 1-9 (2021)
Background There have been several studies carried out to irradiate Helminthiasis however very little research have been carried out where in the enzymatic activity of plants are exploited to antagonize infections. Here we are analyzing the anthelmin
Autor:
Ray Wynford-Thomas, Neil Robertson
Publikováno v:
Journal of Neurology
Neuromyelitis optica spectrum disorder (NMO-SD) has a worldwide prevalence of 0.5–10 persons per 100,000 population. It is characterised by inflammatory events centred on the optic nerve and spinal cord, often with poor recovery and subsequent resi
Autor:
Maike Oldenburg, Silvia Kathrin Eller, Christoph-Martin Ufermann, Walter Däubener, Katrin Spekker-Bosker
Publikováno v:
Medical Microbiology and Immunology
Human retinal pigment epithelial (hRPE) cells form a selectively permeable monolayer between the neural retina and the highly permeable choroidal vessels. Thus, hRPE cells bear important regulatory functions and are potential targets of pathogens in
Autor:
Susan M. Abdel-Rahman, Jonathan B. Wagner, Kayode Ogungbenro, Aleksandra Galetin, J. Steven Leeder
Publikováno v:
European Journal of Clinical Pharmacology
Ogungbenro, K, Wagner, J B, Abdel-Rahman, S, Leeder, J S & Galetin, A 2019, ' A population pharmacokinetic model for simvastatin and its metabolites in children and adolescents ', European journal of clinical pharmacology . https://doi.org/10.1007/s00228-019-02697-y, https://doi.org/10.1007/s00228-019-02697-y
Ogungbenro, K, Wagner, J B, Abdel-Rahman, S, Leeder, J S & Galetin, A 2019, ' A population pharmacokinetic model for simvastatin and its metabolites in children and adolescents ', European journal of clinical pharmacology . https://doi.org/10.1007/s00228-019-02697-y, https://doi.org/10.1007/s00228-019-02697-y
Purpose Poor adherence to dietary/behaviour modifications as interventions for hypercholesterolemia in paediatric patients often necessitates the initiation of statin therapy. The aim of this study was to develop a joint population pharmacokinetic mo
Publikováno v:
Pflugers Archiv
Human embryonic stem cell–derived cardiomyocytes develop pronounced hypertrophy in response to angiotensin-2, endothelin-1, and a selected mix of three fatty acids. All three of these responses are accompanied by increases in both basal cytoplasmic
Autor:
Ben Kirk, Dominic A. Doran, James P. Morton, Simon C. Fleming, Andy Sparks, Robert Fearn, Jamie N. Pugh, Graeme L. Close, Carl Langan-Evans
Publikováno v:
European Journal of Applied Physiology
Purpose To evaluate the effects of probiotic supplementation on gastrointestinal (GI) symptoms, circulatory markers of GI permeability, damage, and markers of immune response during a marathon race. Methods Twenty-four recreational runners were rando
Autor:
Céleste Lebbé, Andrew S. Brohl, Meliessa H. Hennessy, Michele Milella, Patrick Terheyden, Kent C. Shih, Paul Nghiem, Isaac Brownell, Gerald P. Linette, Karl D. Lewis, Shailender Bhatia, Murtuza Bharmal, Omid Hamid, Michael Schlichting, Sandra P. D'Angelo, Janice M. Mehnert, Matthias Hunger
Publikováno v:
Cancer Immunology, Immunotherapy
Background Response rates are primary endpoints in many oncology trials; however, correlation with overall survival (OS) is not uniform across cancer types, treatments, or lines of therapy. This study explored the association between objective respon