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Autor:
Hendrik Schewe, Florence Miramella Schempp, Jia Mi, Ferdinand Kirchner, Markus Buchhaupt, Katharina Elisabeth Hofmann, Jens Schrader, Annika Meffert
Publikováno v:
Applied Microbiology and Biotechnology
Monoterpenoids are widely used in industrial applications, e.g. as active ingredients in pharmaceuticals, in flavor and fragrance compositions, and in agriculture. Severe toxic effects are known for some monoterpenoids making them challenging compoun
Publikováno v:
Parasitology Research
Toxoplasma gondii can infect virtually all warm-blooded animals, including humans. It can differentiate between rapidly replicating tachyzoites that cause acute infection and slowly growing bradyzoites in tissue cysts. Treatment options for toxoplasm
Autor:
Jessica Gierhake, Julian Droste, Alfred Pühler, Susanne Schneiker-Bekel, Lena Schaffert, Jörn Kalinowski, Marcus Persicke, Winfried Dipl Chem Dr Rosen
Publikováno v:
Applied Microbiology and Biotechnology
Actinoplanes sp. SE50/110 (ATCC 31044) is the wild type of industrial producer strains of acarbose. Acarbose has been used since the early 1990s as an inhibitor of intestinal human α-glucosidases in the medical treatment of type II diabetes mellitus
Autor:
Mario Lukacevic, Tobias Borchert, James T. Thackeray, Annika Hess, Frank M. Bengel, Tobias L. Ross
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging
Purpose Myocardial infarction (MI) triggers a local inflammatory response which orchestrates cardiac repair and contributes to concurrent neuroinflammation. Angiotensin-converting enzyme (ACE) inhibitor therapy not only attenuates cardiac remodeling
Autor:
Eric D Gardner, Bryce P. Johnson, Dustin A Dimas, Andrea L Batchev, Susan L. Nimmo, Tejaswi Bavineni, Shanteri Singh, Erin M. Scull, Chandrasekhar Bandari
Publikováno v:
Applied Microbiology and Biotechnology
Abstract Aromatic prenyltransferases are known for their extensive promiscuity toward aromatic acceptor substrates and their ability to form various carbon-carbon and carbon-heteroatom bonds. Of particular interest among the prenyltransferases is Nph
Autor:
Maura Dandri
Publikováno v:
Seminars in Immunopathology
The human hepatitis B virus (HBV) is a small-enveloped DNA virus causing acute and chronic hepatitis. Despite the existence of an effective prophylactic vaccine and the strong capacity of approved antiviral drugs to suppress viral replication, chroni
Autor:
Danuta Wojcieszyńska, Urszula Guzik
Publikováno v:
Applied Microbiology and Biotechnology
Abstract This article summarizes the current knowledge about the presence of naproxen in the environment, its toxicity to nontarget organisms and the microbial degradation of this drug. Currently, naproxen has been detected in all types of water, inc
Autor:
Jason T. Lee, András Füredi, Oliver Langer, R. Michael van Dam, Divya Maheshwari, Theresa Falls, Pavitra Kannan, Gergely Szakács, Severin Mairinger, Sabina Dizdarevic, Jeffrey Collins, Thomas Wanek
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging
Purpose Multidrug resistance (MDR) impedes cancer treatment. Two efflux transporters from the ATP-binding cassette (ABC) family, ABCB1 and ABCG2, may contribute to MDR by restricting the entry of therapeutic drugs into tumor cells. Although a higher
Autor:
B. M. Patil, Aravinda Nagaraj Danappanvar, Saikiran Kulkarni, Belgaonkar Ashwini Subhash, Prarambh Dwivedi
Publikováno v:
In Silico Pharmacol
Postprandial hyperglycemia is associated with an increase in blood glucose levels after a meal, which is further associated with various risk factors like cardiovascular diseases. α-amylase is a digestive enzyme and secreted by the salivary glands a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a6200f120406b283a5deadc75907329
https://europepmc.org/articles/PMC8353021/
https://europepmc.org/articles/PMC8353021/
Autor:
Reza Ranjbar, Amir Mirzaie
Publikováno v:
AMB Express
AMB Express, Vol 11, Iss 1, Pp 1-11 (2021)
AMB Express, Vol 11, Iss 1, Pp 1-11 (2021)
Klebsiella pneumoniaeis a multidrug-resistant (MDR) opportunistic pathogen that causes nosocomial infections. Virulence analysis and molecular typing as powerful approaches can provide relevant information onK. pneumoniaeinfection. In the current stu