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Autor:
Richard Wade-Martins, Marta Cherubini
Publikováno v:
Cell and Tissue Research
Preferential degeneration of dopamine neurons (DAn) in the midbrain represents the principal hallmark of Parkinson's disease (PD). It has been hypothesized that major contributors to DAn vulnerability lie in their unique cellular physiology and archi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5cc9e60b03bb8f6c54f5ed0bb52906
https://ora.ox.ac.uk/objects/uuid:db6025ad-7d2d-4ae5-bd80-6562441e2cb1
https://ora.ox.ac.uk/objects/uuid:db6025ad-7d2d-4ae5-bd80-6562441e2cb1
Autor:
Dirk Lefeber, Ilse Feenstra, Aad Verrips, Sandra L. J. Verhaagen – van den Akker, Wienke H. Galama
Publikováno v:
JIMD Reports ISBN: 9783662578797
A boy presented at the age of 3.5 months with a developmental delay. He developed infantile spasms with hypsarrhytmia on EEG 1 month later. Additional symptoms were delayed visual development, asymmetrical hearing loss, hypotonia, and choreoathetoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcfbc5e1ba8e1d1788da801da0ac770f
https://europepmc.org/articles/PMC6122024/
https://europepmc.org/articles/PMC6122024/
Autor:
Mehul T. Dattani, Vaitsa Tziaferi
Publikováno v:
Endocrine Surgery in Children ISBN: 9783662542545
The pituitary gland protrudes from the base of the brain and is encased by the sphenoid bone. The pituitary and hypothalamus together act as the main regulator of hormone production. The pituitary consists of two distinct parts, the anterior pituitar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64f2524857c9e214cd9e93093be7f6f1
https://doi.org/10.1007/978-3-662-54256-9_32
https://doi.org/10.1007/978-3-662-54256-9_32
Autor:
Pritmohinder S. Gill, Xi Yang, Laura K. Schnackenberg, Jinchun Sun, Richard D. Beger, Laura P. James, Sudeepa Bhattacharyya
Publikováno v:
Archives of Toxicology
Acetaminophen (APAP) is a commonly used analgesic drug that can cause liver injury, liver necrosis and liver failure. APAP-induced liver injury is associated with glutathione depletion, the formation of APAP protein adducts, the generation of reactiv
Autor:
Marlene Thorsen Mørch, Shohreh Issazadeh-Navikas, Thomas Hellesøe Holm, Dina Dræby, Siegfried Weiss, Trevor Owens, Stefan Lienenklaus, Carsten Tue Berg, Ruthe Storgaard Dieu, Reza Khorooshi
Publikováno v:
Acta Neuropathologica
Khorooshi, R, Mørch, M T, Holm, T, Berg, C T, Dieu, R T, Dræby, D, Issazadeh-Navikas, S, Weiss, S, Lienenklaus, S & Owens, T 2015, ' Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis ', Acta Neuropathologica, vol. 130, no. 1, pp. 107-118 . https://doi.org/10.1007/s00401-015-1418-z
Khorooshi, R, Mørch, M T, Holm, T, Berg, C T, Dieu, R T, Dræby, D, Issazadeh-Navikas, S, Weiss, S, Lienenklaus, S & Owens, T 2015, ' Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis ', Acta Neuropathologica, vol. 130, no. 1, pp. 107-118 . https://doi.org/10.1007/s00401-015-1418-z
The Type I interferons (IFN), beta (IFN-β) and the alpha family (IFN-α), act through a common receptor and have anti-inflammatory effects. IFN-β is used to treat multiple sclerosis (MS) and is effective against experimental autoimmune encephalomye
Publikováno v:
Journal of Molecular Medicine (Berlin, Germany)
Journal of molecular medicine 93(8), 905-916 (2015). doi:10.1007/s00109-015-1275-1
Journal of molecular medicine 93(8), 905-916 (2015). doi:10.1007/s00109-015-1275-1
Photooxidative damage and chronic innate immune activation have been implicated in retinal pigment epithelium (RPE) dysfunction, a process that underlies blinding diseases such as age-related macular degeneration (AMD). To identify a potential molecu
Autor:
Pierre Bourgeois, Guus A.M.S. van Dongen, Thomas Guiot, Melanie Vaes, Hendrik Everaert, Patrick Flamen, Danielle J. Vugts, Nathalie Meuleman, Bruno Vanderlinden, Kristoff Muylle, Dominique Bron, Ghanem Elias Ghanem
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging
Muylle, K, Flamen, P, Vugts, D, Guiot, T, Ghanem, G, Meuleman, N, Bourgeois, P, Vanderlinden, B, van Dongen, G A M S, Everaert, H, Vaes, M & Bron, D 2015, ' Tumour targeting and radiation dose of radioimmunotherapy with Y-90-rituximab in CD20+B-cell lymphoma as predicted by Zr-89-rituximab immuno-PET: impact of preloading with unlabelled rituximab ', European Journal of Nuclear Medicine and Molecular Imaging, vol. 42, no. 8, pp. 1304-1314 . https://doi.org/10.1007/s00259-015-3025-6
European journal of nuclear medicine and molecular imaging, 42 (8
European Journal of Nuclear Medicine and Molecular Imaging, 42(8), 1304-1314. Springer Verlag
Muylle, K, Flamen, P, Vugts, D, Guiot, T, Ghanem, G, Meuleman, N, Bourgeois, P, Vanderlinden, B, van Dongen, G A M S, Everaert, H, Vaes, M & Bron, D 2015, ' Tumour targeting and radiation dose of radioimmunotherapy with Y-90-rituximab in CD20+B-cell lymphoma as predicted by Zr-89-rituximab immuno-PET: impact of preloading with unlabelled rituximab ', European Journal of Nuclear Medicine and Molecular Imaging, vol. 42, no. 8, pp. 1304-1314 . https://doi.org/10.1007/s00259-015-3025-6
European journal of nuclear medicine and molecular imaging, 42 (8
European Journal of Nuclear Medicine and Molecular Imaging, 42(8), 1304-1314. Springer Verlag
Purpose: To compare using immuno-PET/CT the distribution of 89Zr-labelled rituximab without and with a preload of unlabelled rituximab to assess the impact of preloading with unlabelled rituximab on tumour targeting and radiation dose of subsequent r
Autor:
Hans-Georg Morhenn, Katrin S. Lips, Reinhard Schnettler, Janet Beckmann, Jan Schubert, Veronika Grau
Publikováno v:
Cell and Tissue Research
Increasing evidence is showing that the non-neuronal cholinergic system plays an important role in the pathology of rheumatoid arthritis (RA). Choline transport into the cell is the rate-limiting step for the synthesis of acetylcholine (ACh), which c
Autor:
Mohd Nasir Mohd Desa, Vasantha K. Neela, Zalina Ismail, Narges Eskandarian, S Amin Nordin, A. van Belkum
Publikováno v:
European Journal of Clinical Microbiology & Infectious Diseases
A total of 103 group B streptococci (GBS) including 22 invasive, 21 non-invasive, and 60 colonizing isolates were collected in a Malaysian hospital (June 2010–October 2011). Isolates were characterized by conventional and molecular serotyping and a
Autor:
M. K. Mohanta, Khanjada Shahnewaj Bin Mannan, Ananda Kumar Saha, D. K. M. A. Saleh, Md. Saiful Islam, Md. Fakruddin
Publikováno v:
3 Biotech
Bacterial disease of silkworm causes significant reduction of silk production leading to huge economic loss. This study aims to isolate bacteria from diseased silkworm and to determine its pathogenicity and antibiotic resistance. A strain of Klebsiel