Zobrazeno 1 - 10
of 113
pro vyhledávání: ''
Publikováno v:
Cell and Tissue Research
Glial cell line–derived neurotrophic factor (GDNF) is a 134 amino acid protein belonging in the GDNF family ligands (GFLs). GDNF was originally isolated from rat glial cell lines and identified as a neurotrophic factor with the ability to promote d
Publikováno v:
Pflugers Archiv
Human embryonic stem cell–derived cardiomyocytes develop pronounced hypertrophy in response to angiotensin-2, endothelin-1, and a selected mix of three fatty acids. All three of these responses are accompanied by increases in both basal cytoplasmic
Publikováno v:
Pain Control ISBN: 9783662464496
Opioids are considered the gold standard for the treatment of moderate to severe pain. However, heterogeneity in analgesic efficacy, poor potency and side effects are associated with opioid use, resulting in dose limitations and suboptimal pain manag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a421842366528ade9c89389f6639d10
https://doi.org/10.1007/978-3-662-46450-2_11
https://doi.org/10.1007/978-3-662-46450-2_11
Dopaminergic neurons regulate and organize numerous important behavioral processes including motor activity. Consistently, manipulation of brain dopamine concentrations changes animal activity levels. Dopamine is synthesized by several neuronal popul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::311ac39a539775f48f46a905b0ab6020
https://europepmc.org/articles/PMC5561950/
https://europepmc.org/articles/PMC5561950/
The NLRP3 inflammasome, which consists of the NLRP3 (nucleotide-binding oligomerization domain (Nod)-like receptor 3) scaffold, the ASC (apoptosis-associated speck-like protein containing a CARD) adaptor and procaspase- 1, is assembled after the cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3580f78655125de904fb0de122bdb419
https://europepmc.org/articles/PMC5561828/
https://europepmc.org/articles/PMC5561828/
Autor:
A. Cleve, B. Haendler, Tim Wintermantel, C. Möller, K.-H. Fritzemeier, Wolfgang Schwede, Nikolaus Heinrich
Publikováno v:
Sex and Gender Differences in Pharmacology ISBN: 9783642307256
Sex steroid receptors are ligand-triggered transcription factors. Oestrogen, progesterone and androgen receptors form, together with the glucocorticoid and mineralocorticoid receptors, a subgroup of the superfamily of nuclear receptors. They share a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5c66b10bd90b1c9ee1dc40f45d42cd5
https://doi.org/10.1007/978-3-642-30726-3_24
https://doi.org/10.1007/978-3-642-30726-3_24
Publikováno v:
Antiplatelet Agents ISBN: 9783642294228
Atherothrombosis is the major cause of mortality and morbidity in Western countries. Several clinical conditions are characterized by increased incidence of cardiovascular events and enhanced thromboxane (TX)-dependent platelet activation. Enhanced T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9557051c4f88717afa873ec01b2ee64
https://doi.org/10.1007/978-3-642-29423-5_11
https://doi.org/10.1007/978-3-642-29423-5_11
Autor:
Adam P. Chambers, Stephen C. Woods
Publikováno v:
Handbook of Experimental Pharmacology ISBN: 9783642247156
When administered into the brain, NPY acts at Y1 and Y5 receptors to increase food intake. The response occurs with a short latency and is quite robust, such that exogenous NPY is generally considered to be the most potent of a growing list of orexig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c46e2b7fdb04206d4174c7fcfa7eeddf
https://doi.org/10.1007/978-3-642-24716-3_2
https://doi.org/10.1007/978-3-642-24716-3_2
Publikováno v:
Muscarinic Receptors ISBN: 9783642232732
Striatal cholinergic interneurons are pivotal modulators of the striatal circuitry involved in action selection and decision making. Although nicotinic receptors are important transducers of acetylcholine release in the striatum, muscarinic receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c86a8ec766e5bb61ef8dbdc3c3651ce0
https://doi.org/10.1007/978-3-642-23274-9_10
https://doi.org/10.1007/978-3-642-23274-9_10
Autor:
Richard M. Eglen
Publikováno v:
Muscarinic Receptors ISBN: 9783642232732
The physiological role of muscarinic receptors is highly complex and, although not completely understood, has become clearer over the last decade. Recent pharmacological evidence with novel compounds, together with data from transgenic mice, suggests
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22d48ad109b93fb489b233206a11ea3e
https://doi.org/10.1007/978-3-642-23274-9_1
https://doi.org/10.1007/978-3-642-23274-9_1