Zobrazeno 31 - 40
of 113
pro vyhledávání: ''
Autor:
J.-C. Schwartz, P. Sokoloff
Publikováno v:
Dopamine in the CNS I ISBN: 9783642627262
The pleiotropic actions of dopamine, as well as of drugs used in the treatment of Parkinson’s disease and schizophrenia, have long been assumed to result from interaction with only two dopamine receptors termed D1 and D2. In spite of previous sugge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0774dceb8dc82a9ee9959e6533a10838
https://doi.org/10.1007/978-3-642-56051-4_7
https://doi.org/10.1007/978-3-642-56051-4_7
Autor:
V. Ralevic
Publikováno v:
Purinergic and Pyrimidinergic Signalling II ISBN: 9783540678489
Purine nucleotides and nucleosides were shown in 1929 to have potent effects on the heart and vasculature, in the first indication that these agents can act as extracellular signalling molecules in the cardiovascular system (Drury and Szent-Gyorgi 19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abc4a611d2a4b42fc7a3f6452f08be06
https://doi.org/10.1007/978-3-642-56921-0_4
https://doi.org/10.1007/978-3-642-56921-0_4
Autor:
Joel Linden, R.M. Broad
Publikováno v:
Purinergic and Pyrimidinergic Signalling II ISBN: 9783540678489
The presence of adenosine receptors on cardiovascular tissues has previously been established on the basis of functional responses to adenosine and adenosine analogs. Specific functions attributed to each of the four adenosine receptor subtypes (A1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::116575d66a2679328d826812a96c5e44
https://doi.org/10.1007/978-3-642-56921-0_1
https://doi.org/10.1007/978-3-642-56921-0_1
Autor:
S. A. Masino, T. V. Dunwiddie
Publikováno v:
Purinergic and Pyrimidinergic Signalling I ISBN: 9783642087424
Purines and pyrimidines present an interesting paradox in the nervous system. Molecules such as adenosine, ATP, and UTP play an essential role in cellular metabolism, and are found in every cell in the brain. Nevertheless, it is now well-established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7658bc76ef8942202a1233eb1c31577a
https://doi.org/10.1007/978-3-662-09604-8_9
https://doi.org/10.1007/978-3-662-09604-8_9
Autor:
J. L. Yakel
Publikováno v:
Pharmacology of Ionic Channel Function: Activators and Inhibitors ISBN: 9783642630309
The 5-HT3 receptor (5-HT3R) is a ligand-gated ion channel gated by the neurotransmitter serotonin (5-HT) and belonging to the superfamily of ligand-gated ion channels, a group that includes nicotinic acetylcholine (ACh), GABA, and glycine receptor ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b43ec28dc446310f05cd04f0a44057d
https://doi.org/10.1007/978-3-642-57083-4_21
https://doi.org/10.1007/978-3-642-57083-4_21
Publikováno v:
Dermatopharmacology of Topical Preparations ISBN: 9783642629600
Given that many skin disorders have an immunologic basis or involve inflammatory reactions, compounds affecting the afferent or the effector limbs of immune responses play a central role in dermatologic therapy. Topical glu-cocorticosteroids (GCs) re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36978e12e94b568d225add28207c82b7
https://doi.org/10.1007/978-3-642-57145-9_12
https://doi.org/10.1007/978-3-642-57145-9_12
Autor:
J.-P. Changeux, L. M. Marubio
Publikováno v:
Handbook of Experimental Pharmacology ISBN: 9783642630279
Nicotinic acetylcholine receptors (nAChRs) are expressed in muscle, the central nervous system (CNS), and the peripheral nervous system (PNS). Nicotine, a specific agonist of these receptors, exerts diverse cellular and behavioural effects. Aside fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::656e2e04634451482630f65ee0f1ad9b
https://doi.org/10.1007/978-3-642-57079-7_20
https://doi.org/10.1007/978-3-642-57079-7_20
Autor:
D. A. Brown
Publikováno v:
Handbook of Experimental Pharmacology ISBN: 9783642630279
Studies on neuronal nicotinic receptors really started with the experiments of LANGLEY and DICKENSON in 1889 on the cat superior cervical ganglion. In fact, they were not particularly interested in the action of nicotine as such, but were employing i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bfad6bb808d9530d0ffae4e015dbb76
https://doi.org/10.1007/978-3-642-57079-7_1
https://doi.org/10.1007/978-3-642-57079-7_1
Publikováno v:
Handbook of Experimental Pharmacology ISBN: 9783642630279
In contrast to the extensively studied nicotinic receptor expressed at the vertebrate neuromuscular junction and electric organs (’muscle type’ nAChRs), the nicotinic receptors expressed in the central and peripheral nervous system (’neuronal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98ed499b987f4cdfb85ba7ec52204329
https://doi.org/10.1007/978-3-642-57079-7_15
https://doi.org/10.1007/978-3-642-57079-7_15
Autor:
R. J. Naylor, B. Costall
Publikováno v:
Serotoninergic Neurons and 5-HT Receptors in the CNS ISBN: 9783540667155
Gaddum and Picarelli(1957), using the guinea pig ileum, were the first researchers to show that 5-hydroxytryptamine (5-HT) can mediate a neuronal depolarising response and release of acetylcholine. A clarification of the nature and function of the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed3a769c9fe3506d615fa98a62a246a3
https://doi.org/10.1007/978-3-642-60921-3_16
https://doi.org/10.1007/978-3-642-60921-3_16