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Publikováno v:
Cell and Tissue Research
Glial cell line–derived neurotrophic factor (GDNF) is a 134 amino acid protein belonging in the GDNF family ligands (GFLs). GDNF was originally isolated from rat glial cell lines and identified as a neurotrophic factor with the ability to promote d
Autor:
Eiichiro Mori, Joachim Luginbühl, Sonia Sabate-Soler, Jens Christian Schwamborn, Silvia Bolognin, Alexander Skupin, Stefano Magni, Kaoru Kinugawa, Kamil Grzyb, Lisa M. Smits, Jay W. Shin
Publikováno v:
Cell and Tissue Research
Human stem cell-derived organoids have great potential for modelling physiological and pathological processes. They recapitulate in vitro the organization and function of a respective organ or part of an organ. Human midbrain organoids (hMOs) have be
Autor:
Mariko Hokari, Masatoyo Nishizawa, Musashi Arakawa, Naomi Mezaki, Jun Tokunaga, Naoko Sakai, Kota Utsumi, Akari Takeshima, Miura Takeshi, Akio Yokoseki, Tetsutaro Ozawa, Atsushi Ishikawa, Ryoko Takeuchi, Takashi Kondo
Publikováno v:
Journal of Neurology
Patients with multiple system atrophy (MSA) often have evidence of compromised gastrointestinal motility. Ghrelin is a gut hormone that influences gastrointestinal motility in humans. The aim of this study was to determine whether ghrelin secretion i
Dopaminergic neurons regulate and organize numerous important behavioral processes including motor activity. Consistently, manipulation of brain dopamine concentrations changes animal activity levels. Dopamine is synthesized by several neuronal popul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::311ac39a539775f48f46a905b0ab6020
https://europepmc.org/articles/PMC5561950/
https://europepmc.org/articles/PMC5561950/
Autor:
John S. Yeomans
Publikováno v:
Muscarinic Receptors ISBN: 9783642232732
All five muscarinic receptor subtypes and mRNAs are found widely in the brain stem, with M₂ muscarinic receptors most concentrated in the hindbrain. Three cholinergic cell groups, Ch5: pedunculopontine (PPT); Ch6: laterodorsal tegmental (LDT); Ch8:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ebf4d98f520438cfe3c1c14d7bd5378
https://doi.org/10.1007/978-3-642-23274-9_11
https://doi.org/10.1007/978-3-642-23274-9_11
Publikováno v:
Muscarinic Receptors ISBN: 9783642232732
Striatal cholinergic interneurons are pivotal modulators of the striatal circuitry involved in action selection and decision making. Although nicotinic receptors are important transducers of acetylcholine release in the striatum, muscarinic receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c86a8ec766e5bb61ef8dbdc3c3651ce0
https://doi.org/10.1007/978-3-642-23274-9_10
https://doi.org/10.1007/978-3-642-23274-9_10
Autor:
Richard M. Eglen
Publikováno v:
Muscarinic Receptors ISBN: 9783642232732
The physiological role of muscarinic receptors is highly complex and, although not completely understood, has become clearer over the last decade. Recent pharmacological evidence with novel compounds, together with data from transgenic mice, suggests
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22d48ad109b93fb489b233206a11ea3e
https://doi.org/10.1007/978-3-642-23274-9_1
https://doi.org/10.1007/978-3-642-23274-9_1
Publikováno v:
Results and Problems in Cell Differentiation ISBN: 9783642144257
Sweet taste perception is important for animals to detect carbohydrate source of calories and has a critical role in the nutritional status of animals. Recent studies demonstrated that sweet taste responses can be modulated by leptin and endocannabin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49b7892934e0e6688af998fb3d186128
https://doi.org/10.1007/978-3-642-14426-4_9
https://doi.org/10.1007/978-3-642-14426-4_9
Autor:
Francine M. Benes
Publikováno v:
Behavioral Neurobiology of Bipolar Disorder and its Treatment ISBN: 9783642157561
Over the past 15 years, postmortem studies of the corticolimbic system in subjects with bipolar disorder (BPD) have demonstrated a variety of abnormalities affecting the gamma aminobutyric acid (GABA)ergic system. Although some of the changes are sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ced66d25a740326f366b4f59d6bb1e85
https://doi.org/10.1007/7854_2010_75
https://doi.org/10.1007/7854_2010_75
Autor:
Timothy B. Mapstone, Anna J. Janss
Publikováno v:
Oncology of CNS Tumors ISBN: 9783642028731
The pineal gland, located at the roof of the diencephalon, is a cone-shaped structure dorsal to the midbrain tectum. It is composed of a variety of cells, including astrocytes, ganglion cells, blood vessels, and pinocytes. Pineocytes, the parenchymal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::029c22060a28abb42cb7e22c1ebc2d14
https://doi.org/10.1007/978-3-642-02874-8_40
https://doi.org/10.1007/978-3-642-02874-8_40