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Autor:
Jonathan Sprent, S. Sun
Publikováno v:
Immunobiology of Bacterial CpG-DNA ISBN: 9783642640773
As a result of early studies on mycobacteria (Tokunaga et al. 1992; Yamamoto et al. 1992), it is now well established that DNA from nonvertebrates, as well as certain synthetic oligodeoxynucleotides (ODNs), can cause strong activation of lymphoid cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbf401f1851d12408a29afebc249dc53
https://doi.org/10.1007/978-3-642-59672-8_7
https://doi.org/10.1007/978-3-642-59672-8_7
Publikováno v:
Handbook of Experimental Pharmacology ISBN: 9783642630231
The availability of highly potent human immunodeficiency virus (HIV)-1- protease inhibitors has revolutionized both our ability to treat people infected with HIV-1 and our view of how to use antiretroviral agents. Some clinical benefit was obtained w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42cacee1464645bf03fa1418016b4f4b
https://doi.org/10.1007/978-3-642-57092-6_3
https://doi.org/10.1007/978-3-642-57092-6_3
Publikováno v:
Immunobiology of Bacterial CpG-DNA ISBN: 9783642640773
More than 1 billion children in 182 countries throughout the world have been vaccinated with the Bacillus of Calmette and Guerin (BCG) against tuberculosis. BCG appears to be able to elicit protective cell-mediated immune responses in the absence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1576ff545bdfd9ec5dc5677940cf2e3a
https://doi.org/10.1007/978-3-642-59672-8_2
https://doi.org/10.1007/978-3-642-59672-8_2
Autor:
P. Fitzgerald-Bocarsly
Publikováno v:
Interferon: The Dawn of Recombinant Protein Drugs ISBN: 9783662037898
Interferon (IFN), and in specific, type I interferon, has the distinction of being the first cytokine, or as we now recognize, family of cytokines to be discovered. Interferon was first described by Isaacs and Lindenmann in 1957 [1] as a transferable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9f818fd8c2b2403ef625a0f473251d7
https://doi.org/10.1007/978-3-662-03787-4_4
https://doi.org/10.1007/978-3-662-03787-4_4
Autor:
H. O. McDevitt, C. I. Pearson
Publikováno v:
Current Topics in Microbiology and Immunology ISBN: 9783662097113
The immune system’s ability to distinguish between self and non-self relies on the intricate regulation of cellular responses to antigens presented by major histocompatibility complex (MHC) molecules to T cells. These responses include those of T h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd82fc8a9dee65fc0eeb2ef9a8f78799
https://doi.org/10.1007/978-3-662-09709-0_5
https://doi.org/10.1007/978-3-662-09709-0_5
Autor:
S. J. H. van Deventer, T. van der Poll
Publikováno v:
Yearbook of Intensive Care and Emergency Medicine ISBN: 9783540652885
Interleukin (IL)-6 is a member of the cytokine network that can not be simply classified as a pro- or an anti-inflammatory cytokine. It was originally described under many different names, including interferon (IFN)-β2, 26K factor, B-cell stimulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afde5b349efb67a6be2c80bb8a7719b5
https://doi.org/10.1007/978-3-662-13453-5_5
https://doi.org/10.1007/978-3-662-13453-5_5
Autor:
Michel Jourdan, Z. Y. Lu, John Wijdenes, E. Claret, Bernard Klein, Jean Brochier, X. Y. Li, Karin Tarte, Jean-François Rossi
Publikováno v:
Current Topics in Microbiology and Immunology ISBN: 9783642642838
IL-6 is now recognized as a major survival and proliferation factor for murine and human malignant plasma cells (Klein et al 1995; Lattanzio et al 1997). This is especially true for patients with terminal multiple myeloma and extramedullar proliferat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09ead16fc0776e40cc619c061284e09e
https://doi.org/10.1007/978-3-642-60162-0_41
https://doi.org/10.1007/978-3-642-60162-0_41
Autor:
Douglas W. Leaman
Publikováno v:
Inhibitors of Cell Growth ISBN: 9783642721519
The interferons (IFNs) are a family of cytokines that elicit pleiotropic biological effects (Pestka et al. 1987; DeMaeyer and DeMaeyer-Guignard 1988; Sen and Lengyel 1992). Although best known (and named) for their ability to inhibit viral replicatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a325967a0a0bf04934f6704b5237e488
https://doi.org/10.1007/978-3-642-72149-6_6
https://doi.org/10.1007/978-3-642-72149-6_6
Autor:
Douglas M. Stocco
Publikováno v:
Testicular Function: From Gene Expression to Genetic Manipulation ISBN: 9783662036730
Steroid hormones share a common characteristic in that, regardless of the tissue of origin or the final steroid synthesized, they all arise from a common precursor substrate, cholesterol. Thus the biosynthesis of all steroids begins with the cleavage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c2fb4df5f67630eedb8aa372f77a89f
https://doi.org/10.1007/978-3-662-03671-6_10
https://doi.org/10.1007/978-3-662-03671-6_10
Publikováno v:
Plant Proteins from European Crops ISBN: 9783662037225
Purification of trypsin inhibitors from winter pea seeds (c.v. Frilene) showed that the six inhibitors were closely related to one another and belonged to the Bowman-Birk family. The sequence and the biosynthetic mechanism of the isoform formation we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48a63570ebadaf9a48f6f645bbbb718d
https://doi.org/10.1007/978-3-662-03720-1_4
https://doi.org/10.1007/978-3-662-03720-1_4