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Autor:
A. Cleve, B. Haendler, Tim Wintermantel, C. Möller, K.-H. Fritzemeier, Wolfgang Schwede, Nikolaus Heinrich
Publikováno v:
Sex and Gender Differences in Pharmacology ISBN: 9783642307256
Sex steroid receptors are ligand-triggered transcription factors. Oestrogen, progesterone and androgen receptors form, together with the glucocorticoid and mineralocorticoid receptors, a subgroup of the superfamily of nuclear receptors. They share a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5c66b10bd90b1c9ee1dc40f45d42cd5
https://doi.org/10.1007/978-3-642-30726-3_24
https://doi.org/10.1007/978-3-642-30726-3_24
Autor:
J.-P. Changeux, L. M. Marubio
Publikováno v:
Handbook of Experimental Pharmacology ISBN: 9783642630279
Nicotinic acetylcholine receptors (nAChRs) are expressed in muscle, the central nervous system (CNS), and the peripheral nervous system (PNS). Nicotine, a specific agonist of these receptors, exerts diverse cellular and behavioural effects. Aside fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::656e2e04634451482630f65ee0f1ad9b
https://doi.org/10.1007/978-3-642-57079-7_20
https://doi.org/10.1007/978-3-642-57079-7_20
Autor:
R. J. Naylor, B. Costall
Publikováno v:
Serotoninergic Neurons and 5-HT Receptors in the CNS ISBN: 9783540667155
Gaddum and Picarelli(1957), using the guinea pig ileum, were the first researchers to show that 5-hydroxytryptamine (5-HT) can mediate a neuronal depolarising response and release of acetylcholine. A clarification of the nature and function of the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed3a769c9fe3506d615fa98a62a246a3
https://doi.org/10.1007/978-3-642-60921-3_16
https://doi.org/10.1007/978-3-642-60921-3_16
Publikováno v:
Estrogens and Antiestrogens I ISBN: 9783642636677
Antiestrogens are established as compounds which predominantly exert their actions by competing with estrogen for binding to the target steroid receptor. This is evidenced by the observations that their biological effects are most notably recognised
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87655cde5995df92c22fbab9bd19cdb9
https://doi.org/10.1007/978-3-642-58616-3_10
https://doi.org/10.1007/978-3-642-58616-3_10
Autor:
Michael D. Hayward, Malcolm J. Low
Publikováno v:
Results and Problems in Cell Differentiation ISBN: 9783662129081
The opioid system is a powerful modulator of pain and pleasure. Membrane-bound receptors that bind opioid drugs have been identified and characterized pharmacologically, and the genes that encode these receptors have been cloned and mapped to their c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d880dc10795493fd84403d2323f35cf
https://doi.org/10.1007/978-3-540-49421-8_8
https://doi.org/10.1007/978-3-540-49421-8_8
Publikováno v:
Handbook of Experimental Pharmacology ISBN: 9783642642616
The discovery of the second type of estrogen receptor (ER), ER β (KUIPER et al. 1996), changed the way we understand the physiological and pharmacological actions of estrogens and anti estrogens. The findings of multiple isoforms of ER ,β (CHU and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a39651ae6887a5642d4040b4ae21961
https://doi.org/10.1007/978-3-642-60107-1_2
https://doi.org/10.1007/978-3-642-60107-1_2
Autor:
B. L. Kieffer
Publikováno v:
Handbook of Experimental Pharmacology ISBN: 9783642645501
Opiates, the prototype of which is morphine, are the most potent available analgesic compounds. They also are strong addictive drugs. Opiates act by mimicking endogenous opioid peptides and specifically activate membrane receptors of the nervous syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50211a57ef538d5a65056d50f6c21064
https://doi.org/10.1007/978-3-642-60777-6_11
https://doi.org/10.1007/978-3-642-60777-6_11
Publikováno v:
Signaling Mechanisms in Protozoa and Invertebrates ISBN: 9783642801082
The group of compounds collectively called opioids includes both opiate alkaloids of medical importance such as morphine and heroin and endogenous opioid peptides such as met- and leu-enkephalin, β-endorphin, and dynorphin (Simon and Hiller 1994). O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03ea9bb8eaf10d34160ff520bb90b2d7
https://doi.org/10.1007/978-3-642-80106-8_2
https://doi.org/10.1007/978-3-642-80106-8_2
Autor:
Peter L. Amlot
Publikováno v:
Monoclonal Antibodies in Transplantation ISBN: 9783662221976
The immune system is economical with the number of antigen specific cells available to counter intermittent and infrequent antigenic challenges from infectious organisms and relies upon rapid cellular expansion in times of need. Cellular recognition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28c96b9932136a28acb49491d7f9b060
https://doi.org/10.1007/978-3-662-22195-2_3
https://doi.org/10.1007/978-3-662-22195-2_3
Autor:
Robert E. Garfield, Kristof Chwalisz
Publikováno v:
Basic Mechanisms Controlling Term and Preterm Birth
1 Control of Myometrial Contractility and Labor.- 2 Receptors and Signal Transduction in the Myometrium.- 3 Myometrial Electrophysiology.- 4 Role of Uterine Ca2+ Pumps and Na+ Pumps in Labor: A Molecular Biology Approach.- 5 Mechanism of Action of St
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa43e009490375d94d75853332610b27
https://doi.org/10.1007/978-3-662-21660-6
https://doi.org/10.1007/978-3-662-21660-6