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Autor:
Mary C. Olmstead, Alexandra Hertz, Romain Bourdy, Yannick Goumon, Katia Befort, Dominique Filliol, Virginie Andry, Jorge E. Mendoza
Publikováno v:
European Journal of Nutrition
European Journal of Nutrition, Springer Verlag, 2021, ⟨10.1007/s00394-021-02613-0⟩
European Journal of Nutrition, 2021, 60 (8), pp.4621-4633. ⟨10.1007/s00394-021-02613-0⟩
European Journal of Nutrition, Springer Verlag, 2021, ⟨10.1007/s00394-021-02613-0⟩
European Journal of Nutrition, 2021, 60 (8), pp.4621-4633. ⟨10.1007/s00394-021-02613-0⟩
Objectives Increased availability of high-calorie palatable food in most countries has resulted in overconsumption of these foods, suggesting that excessive eating is driven by pleasure, rather than metabolic need. The behavior contributes to the ris
Publikováno v:
Cancer Immunology, Immunotherapy
Bruton’s tyrosine kinase (BTK) is a non-receptor kinase belonging to the Tec family of kinases. The role of BTK in B cell receptor signaling is well defined and is known to play a key role in the proliferation and survival of malignant B cells. Mor
Autor:
Martin Diener, Jasmin Ballout
Publikováno v:
Pflugers Archiv
Propionate, a metabolite from the microbial fermentation of carbohydrates, evokes a release of epithelial acetylcholine in rat caecum resulting in an increase of short-circuit current (Isc) in Ussing chamber experiments. The present experiments were
Publikováno v:
Annals of Hematology
The B cell surface antigen CD19 is a target for treating B cell malignancies, such as B cell precursor acute lymphoblastic leukemia and B cell non-Hodgkin lymphoma. The BiTE® immuno-oncology platform includes blinatumomab, which is approved for rela
Publikováno v:
Pflugers Archiv
Prostacyclin, or PGI2, is a product of PGI synthase (PGIS), down-stream of cyclooxygenase pathway. PGI2 has been demonstrated to play an important role in maintaining renal blood flow. Non-steroidal anti-inflammatory drugs (NSAIDs) that inhibit cyclo
Autor:
Ralf Gold, Aiden Haghikia, Maren Peschke, Gisa Ellrichmann, Kerstin Hellwig, De-Hyung Lee, Jan Bolz, Alexander Duscha, Ralf A. Linker
Publikováno v:
Journal of Neurology
Background With ocrelizumab another drug is available for the treatment of multiple sclerosis (MS). Little is known on the long-term use of ocrelizumab on immune cell subsets, and no surrogate markers are available. Rituximab (RTX) has been in off-la
Publikováno v:
Essentials of Diagnostic Pathology ISBN: 9783662603079
The normal red blood cell count is kept by the balance between erythrocyte production and erythrocyte destruction. The regulation of progenitor cells to the erythroid lineage and their maturation are controlled by growth factors, cytokines and, very
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15ff9657540c02a53b23deefb27d3586
https://doi.org/10.1007/978-3-662-60309-3_2
https://doi.org/10.1007/978-3-662-60309-3_2
Autor:
Klaus Schmierer, Francesca Ammoscato, Helen Lock, David Baker, Zhifeng Mao, Bryan Ceronie, Hilary Longhurst, Benjamin Meir Jacobs, Nicolas Dubuisson, Gavin Giovannoni
Publikováno v:
Journal of Neurology
Background The mechanism of action of oral cladribine, recently licensed for relapsing multiple sclerosis, is unknown. Objective To determine whether cladribine depletes memory B cells consistent with our recent hypothesis that effective, disease-mod
Autor:
Mehul T. Dattani, Vaitsa Tziaferi
Publikováno v:
Endocrine Surgery in Children ISBN: 9783662542545
The pituitary gland protrudes from the base of the brain and is encased by the sphenoid bone. The pituitary and hypothalamus together act as the main regulator of hormone production. The pituitary consists of two distinct parts, the anterior pituitar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64f2524857c9e214cd9e93093be7f6f1
https://doi.org/10.1007/978-3-662-54256-9_32
https://doi.org/10.1007/978-3-662-54256-9_32
Autor:
Marlene Thorsen Mørch, Shohreh Issazadeh-Navikas, Thomas Hellesøe Holm, Dina Dræby, Siegfried Weiss, Trevor Owens, Stefan Lienenklaus, Carsten Tue Berg, Ruthe Storgaard Dieu, Reza Khorooshi
Publikováno v:
Acta Neuropathologica
Khorooshi, R, Mørch, M T, Holm, T, Berg, C T, Dieu, R T, Dræby, D, Issazadeh-Navikas, S, Weiss, S, Lienenklaus, S & Owens, T 2015, ' Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis ', Acta Neuropathologica, vol. 130, no. 1, pp. 107-118 . https://doi.org/10.1007/s00401-015-1418-z
Khorooshi, R, Mørch, M T, Holm, T, Berg, C T, Dieu, R T, Dræby, D, Issazadeh-Navikas, S, Weiss, S, Lienenklaus, S & Owens, T 2015, ' Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis ', Acta Neuropathologica, vol. 130, no. 1, pp. 107-118 . https://doi.org/10.1007/s00401-015-1418-z
The Type I interferons (IFN), beta (IFN-β) and the alpha family (IFN-α), act through a common receptor and have anti-inflammatory effects. IFN-β is used to treat multiple sclerosis (MS) and is effective against experimental autoimmune encephalomye