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Autor:
P. K. Weck, P. E. Came
Publikováno v:
Interferons and Their Applications ISBN: 9783642691805
Interferons have been shown to have a number of biologic activities other than the antiviral properties which first led to their discovery. Since the identification of interferon by Issacs and Lindenmann in 1957, numerous studies have been directed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4b93ea8d8540f63a3c4bfbdab6c3d03
https://doi.org/10.1007/978-3-642-69178-2_16
https://doi.org/10.1007/978-3-642-69178-2_16
Autor:
V. G. Edy
Publikováno v:
Interferons and Their Applications ISBN: 9783642691805
It is rather trite to point out that, as experiments are performed and results published, our understanding of a scientific problem usually becomes more sophisticated, and on occasion also more correct. This truism is especially applicable to the sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a967bdc13a44b4a808ab579a8fc7a675
https://doi.org/10.1007/978-3-642-69178-2_14
https://doi.org/10.1007/978-3-642-69178-2_14
Autor:
Robert Volpé
Publikováno v:
Auto-immunity in the Endocrine System ISBN: 9783642816260
The term “immunity” may be defined as those physiological mechanisms which endow the organism with the capacity to recognize substances as foreign, and to neutralize, eliminate or metabolize them without injury to its own tissues. Responses to su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67cd8d3ad4490163c73698e0455ec626
https://doi.org/10.1007/978-3-642-81624-6_1
https://doi.org/10.1007/978-3-642-81624-6_1
Publikováno v:
Interferons and Their Applications ISBN: 9783642691805
Although interferon (IFN) was discovered by virtue of its antiviral effect, an activity which indeed defines it, a large body of literature now documents that IFN can also have significant effects on uninfected cells. The range of these effects is ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::520052ee9cccc9b815ce5cfa018967cf
https://doi.org/10.1007/978-3-642-69178-2_9
https://doi.org/10.1007/978-3-642-69178-2_9
Autor:
M. A. S. Moore
Publikováno v:
Leukemia ISBN: 9783642697241
Studies of myeloid leukemic cell lines and primary cultures of leukemic bone marrow have yielded information on humoral regulation of growth and differentiation of myeloid cells and have revealed specific abnormalities in regulatory control that woul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f99ebd7132ca4174411ab4f702a6941
https://doi.org/10.1007/978-3-642-69722-7_4
https://doi.org/10.1007/978-3-642-69722-7_4
Autor:
P. H. Hofschneider, R. Kandolf
Publikováno v:
Viral Heart Disease ISBN: 9783540131120
Coxsackie viruses, particularly those of group B (types 1–5) are the most frequent reported cause of acute viral myocarditis [1–3]. These viruses have repeatedly been isolated from heart tissue and pericardial fluid at postmortem [4] and it would
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb3b613b76016e922facc8fb43e61c5d
https://doi.org/10.1007/978-3-642-95448-1_7
https://doi.org/10.1007/978-3-642-95448-1_7
Publikováno v:
Lectins and Glycoconjugates in Oncology ISBN: 9783642736643
It is well accepted that the important effectors of natural resistance against tumor, such as natural killer (NK) cells and macrophages share some similarities in that they do not require prior sensitization (5,11), can lyse across HLA or H2 barriers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f64a9f1ef3452e4353d6f18dd8216dbc
https://doi.org/10.1007/978-3-642-73662-9_18
https://doi.org/10.1007/978-3-642-73662-9_18
Autor:
Philip I. Marcus
Publikováno v:
Interferons and Their Applications ISBN: 9783642691805
Interferon was discovered when Isaacs and Lindenmann (1957) infected fragments of chick chorioallantoic membrane with heat-inactivated influenza virus. The viral component or components responsible for interferon induction were not identified then, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20f8ddf71af9b89f81e91534dbaeb42e
https://doi.org/10.1007/978-3-642-69178-2_10
https://doi.org/10.1007/978-3-642-69178-2_10
Publikováno v:
Interferons and Their Applications ISBN: 9783642691805
Leukocyte interferon for clinical trials became available in the early 1970s, the bulk of which was provided from Finland by Cantell et al. (1974) and Strander and CAntell (1966). Fresh buffy coat cells from human blood were stimulated to produce int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffd9c3090d581715581f6d3c37a33383
https://doi.org/10.1007/978-3-642-69178-2_17
https://doi.org/10.1007/978-3-642-69178-2_17
Autor:
S. Panem
Publikováno v:
Interferons and Their Applications ISBN: 9783642691805
Interferon (IFN) has captured the imagination of the virologic community (and only more recently those concerned with cancer therapy), since its discovery in 1957. However, the lack of adequate quantities of high purity IFN has hampered basic researc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d97b67216e19d143f5935b6829f368d
https://doi.org/10.1007/978-3-642-69178-2_7
https://doi.org/10.1007/978-3-642-69178-2_7