Zobrazeno 1 - 10
of 198
pro vyhledávání: ''
Publikováno v:
Analytical and Bioanalytical Chemistry
Tuberculosis (TB) is one of the main infectious diseases worldwide and accounts for many deaths. It is caused by Mycobacterium tuberculosis usually affecting the lungs of patients. Early diagnosis and treatment are essential to control the TB epidemi
Publikováno v:
Cancer Immunology, Immunotherapy
Bruton’s tyrosine kinase (BTK) is a non-receptor kinase belonging to the Tec family of kinases. The role of BTK in B cell receptor signaling is well defined and is known to play a key role in the proliferation and survival of malignant B cells. Mor
Autor:
G. Tridente, Martin Raithel, Leonard B. Weinstock, H.-J. Hertfelder, Franz Ludwig Dumoulin, Jürgen Homann, G. J. Qagish, Gerhard J. Molderings, J. Textor, V. S. Schäfer, R. Barion, D. Klingmüller, Lawrence B. Afrin, B. Sido, D. Berdel, M. Mücke
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology
Omalizumab is an effective therapeutic humanized murine IgE antibody in many cases of primary systemic mast cell activation disease (MCAD). The present study should enable the clinician to recognize when treatment of MCAD with omalizumab is contraind
Autor:
Maura Dandri
Publikováno v:
Seminars in Immunopathology
The human hepatitis B virus (HBV) is a small-enveloped DNA virus causing acute and chronic hepatitis. Despite the existence of an effective prophylactic vaccine and the strong capacity of approved antiviral drugs to suppress viral replication, chroni
Autor:
Maike Oldenburg, Silvia Kathrin Eller, Christoph-Martin Ufermann, Walter Däubener, Katrin Spekker-Bosker
Publikováno v:
Medical Microbiology and Immunology
Human retinal pigment epithelial (hRPE) cells form a selectively permeable monolayer between the neural retina and the highly permeable choroidal vessels. Thus, hRPE cells bear important regulatory functions and are potential targets of pathogens in
Autor:
Céleste Lebbé, Andrew S. Brohl, Meliessa H. Hennessy, Michele Milella, Patrick Terheyden, Kent C. Shih, Paul Nghiem, Isaac Brownell, Gerald P. Linette, Karl D. Lewis, Shailender Bhatia, Murtuza Bharmal, Omid Hamid, Michael Schlichting, Sandra P. D'Angelo, Janice M. Mehnert, Matthias Hunger
Publikováno v:
Cancer Immunology, Immunotherapy
Background Response rates are primary endpoints in many oncology trials; however, correlation with overall survival (OS) is not uniform across cancer types, treatments, or lines of therapy. This study explored the association between objective respon
Autor:
Rodrigo Correa-Oliveira, David I. Pritchard, Jeffrey M. Bethony, Maria Elena Bottazzi, David Diemert, John M. Hawdon
In this chapter, we describe the scientific, technical, clinical and regulatory aspects of establishing a controlled human hookworm infection (CHHI) model in non-endemic and endemic geographical regions, to facilitate a pathway towards accelerated va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ede959308c5f047fe8cf1bca637b7831
https://doi.org/10.1007/82_2021_237
https://doi.org/10.1007/82_2021_237
Autor:
Bengt Sjögren, Eva Andersson, Karine Elihn, Lennart Andersson, Bodil Persson, Håkan Westberg, Cathe Karlsson, Ing Liss Bryngelsson
Publikováno v:
International Archives of Occupational and Environmental Health
To study the relationship between exposure to airborne particles in a pulp and paper mill and markers of inflammation and coagulation in blood. Personal sampling of inhalable dust was performed for 72 subjects working in a Swedish pulp and paper mill
Autor:
Marlene Thorsen Mørch, Shohreh Issazadeh-Navikas, Thomas Hellesøe Holm, Dina Dræby, Siegfried Weiss, Trevor Owens, Stefan Lienenklaus, Carsten Tue Berg, Ruthe Storgaard Dieu, Reza Khorooshi
Publikováno v:
Acta Neuropathologica
Khorooshi, R, Mørch, M T, Holm, T, Berg, C T, Dieu, R T, Dræby, D, Issazadeh-Navikas, S, Weiss, S, Lienenklaus, S & Owens, T 2015, ' Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis ', Acta Neuropathologica, vol. 130, no. 1, pp. 107-118 . https://doi.org/10.1007/s00401-015-1418-z
Khorooshi, R, Mørch, M T, Holm, T, Berg, C T, Dieu, R T, Dræby, D, Issazadeh-Navikas, S, Weiss, S, Lienenklaus, S & Owens, T 2015, ' Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis ', Acta Neuropathologica, vol. 130, no. 1, pp. 107-118 . https://doi.org/10.1007/s00401-015-1418-z
The Type I interferons (IFN), beta (IFN-β) and the alpha family (IFN-α), act through a common receptor and have anti-inflammatory effects. IFN-β is used to treat multiple sclerosis (MS) and is effective against experimental autoimmune encephalomye
Autor:
Elahe Motevaseli, Alireza Shirazi, Masoud Najafi, Gh. Geraily, M. Heidari, Saeed Rezapoor, F. Norouzi
Radiotherapy has a key role in cancer treatment in more than half of patients with cancer. The management of severe side effects of this treatment modality is a limiting factor to appropriate treatment. Immune system responses play a pivotal role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9dec20f2aca5f0aecd7213fa76f3882
https://europepmc.org/articles/PMC5425818/
https://europepmc.org/articles/PMC5425818/