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Autor:
Peter L. Amlot
Publikováno v:
Monoclonal Antibodies in Transplantation ISBN: 9783662221976
The immune system is economical with the number of antigen specific cells available to counter intermittent and infrequent antigenic challenges from infectious organisms and relies upon rapid cellular expansion in times of need. Cellular recognition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28c96b9932136a28acb49491d7f9b060
https://doi.org/10.1007/978-3-662-22195-2_3
https://doi.org/10.1007/978-3-662-22195-2_3
Publikováno v:
Cerebellar Infarct. Midline Tumors. Minimally Invasive Endoscopic Neurosurgery (MIEN) ISBN: 9783540576686
Failing defense mechanisms against malignant tumors are thought to be caused by low immunogenicity of tumor cells and defective T helper cell functions. The concept of associate recognition by Lake and Mitchison [5] posits the necessity of at least t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eca52e141b9a951add3d159b36340922
https://doi.org/10.1007/978-3-642-78801-7_31
https://doi.org/10.1007/978-3-642-78801-7_31
Publikováno v:
Leukemias ISBN: 9783642770852
Interleukin-2 (IL-2), originally described as T cell growth factor by Morgan et al. in 1975 [29], is the first of a new kind of immunotherapeutic agents which work against established tumors through the modulation of host immune functions. Cloning of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1329ac1b93f069b4da64241c37f17d0b
https://doi.org/10.1007/978-3-642-77083-8_18
https://doi.org/10.1007/978-3-642-77083-8_18
Publikováno v:
Lymphohaematopoietic Growth Factors in Cancer Therapy ISBN: 9783642760396
The immune system possesses distinct effector mechanisms that destroy not-self as well as self-altered cells. Their power is so high that the system devotes great care to their induction, coordination and modulation. The intricacy of regulatory manoe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e416bcc2dc1959f517b56c549daae4e8
https://doi.org/10.1007/978-3-642-76037-2_5
https://doi.org/10.1007/978-3-642-76037-2_5
Publikováno v:
Cytokines in Hemopoiesis, Oncology, and AIDS ISBN: 9783540522812
The CD4 molecule, a 55–60 kDa glycoprotein, is expressed on the surface of a helper/inducer subset of human T cells that mediates the interaction of T cells with cells bearing MHC class II proteins during an immune response [9]. In addition to its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae9a6e6256c15a0120a275d6d15bbf5d
https://doi.org/10.1007/978-3-642-75510-1_8
https://doi.org/10.1007/978-3-642-75510-1_8
Autor:
J. R. Lamb, J. B. Rothbard
Publikováno v:
T-Cell Paradigms in Parasitic and Bacterial Infections ISBN: 9783642749858
T-lymphocytes are integral in the generation of virtually all the effector functions of the vertebrate immune response. They can be divided broadly into two populations based on the surface expression of either the CD4 or CD8 glycoprotein (Littman 19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::621699f6cd478b91c19445567783d1f4
https://doi.org/10.1007/978-3-642-74983-4_10
https://doi.org/10.1007/978-3-642-74983-4_10
Autor:
S P Feldman, Salvatore Venuta, V J Merluzzi, Karl Welte, Neal Flomenberg, H. J. Feickert, R Mertelsmann, Malcom A.S. Moore, G. Kruger, Chang Yi Wang, N. Ciobanu
Publikováno v:
Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ISBN: 9783540118589
The regulation of immune function [6] and tumor growth [16] by hormone-like factors, cytokines, has become the subject of increasing interest. Interleukin 2 (IL2) discovered by Morgan et al. [5], is produced by T-lymphocytes after antigen or mitogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::663de941fbed9b29449c40b662f7ecb2
https://doi.org/10.1007/978-3-642-68761-7_72
https://doi.org/10.1007/978-3-642-68761-7_72
Autor:
A. Schimpl
Publikováno v:
Current Topics in Microbiology and Immunology ISBN: 9783642683718
In recent years, the notion has become generally accepted that the highly antigen-specific immune reactions which take place after the introduction of an antigen into an immunocompetent organism either are enhanced by or even critically depend on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd9e27f5bf1ba02850943b7f6138e0d9
https://doi.org/10.1007/978-3-642-68369-5_6
https://doi.org/10.1007/978-3-642-68369-5_6
Autor:
F. Pazderka
Publikováno v:
Realm of Tolerance ISBN: 9783642747144
It is well established that the autologous mixed lymphocyte reaction (AMLR) represents an immunologic response of T cells to surface antigens on autologous nonT cells. Autologous mixed lymphocyte culture (AMLC) has been shown to possess two main attr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f635a3428d144838b79681ca97e8d4ae
https://doi.org/10.1007/978-3-642-74712-0_8
https://doi.org/10.1007/978-3-642-74712-0_8