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Autor:
Charalampos Aslanidis, Gerd Schmitz
Publikováno v:
Rapid Cycle Real-Time PCR ISBN: 9783540667360
Protease inhibitor 1 (αl-antitrypsin, AT) is the main serum inhibitor of proteolytic enzymes. In AT-deficiency, enzymes such as neutrophil elastase can damage the lung tissues, leading to pulmonary emphysema. More than 90 different alleles have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c037ff303c65d56a144e915e0d99f8f
https://doi.org/10.1007/978-3-642-59524-0_8
https://doi.org/10.1007/978-3-642-59524-0_8
Publikováno v:
Archives of Toxicology ISBN: 9783540086468
Previously suggested identity of soluble hepatic carboxylesterase and cytosolic aldehyde dehydrogenase was studied in the liver of the rr and RR rat substrains after phenobarbital administration. Results showed over 30% increase of carboxylesterase a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b25afd84adcc2ddbd56660881f2e891a
https://doi.org/10.1007/978-3-642-66896-8_55
https://doi.org/10.1007/978-3-642-66896-8_55
Autor:
Osmo Hänninen, Pirjo Lindström-Seppä
Publikováno v:
Archives of Toxicology ISBN: 9783540165897
The inducibility of the freshwater crayfish (Astacus astacus) bio-transformation enzymes with model inducers (Aroclor 1254, β-Naphthoflavone, Phenobarbital) were investigated three days after intra cephalothoracic injection in the fasting crayfish a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d315670dc3878455783e9bd55fae8901
https://doi.org/10.1007/978-3-642-71248-7_73
https://doi.org/10.1007/978-3-642-71248-7_73
Autor:
Kerstin Hjalmarsson
Publikováno v:
Advances in Forensic Haemogenetics ISBN: 9783540165002
Human blood coagulation factor 13, the fibrin stabilizing factor, is a zymogen which after activation by thrombin and calcium ions catalyses the formation of γ -glutamyl- e -lysine cross links between fibrin molecules (Losowsky and Miloszewski, 1977
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23341816260d3cea847b503214fa2bde
https://doi.org/10.1007/978-3-642-71150-3_55
https://doi.org/10.1007/978-3-642-71150-3_55
Publikováno v:
Modern Trends in Human Leukemia IV ISBN: 9783540106227
Gene amplification has been recently shown to play a pivotal role in the development of resistance to the folate analogue, methotrexate (MTX), in several cell culture systems (Schimke et al. 1978). Stepwise increases in the concentration of MTX suppl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9f40f4b354187c3294a53cd99faafb0
https://doi.org/10.1007/978-3-642-67984-1_28
https://doi.org/10.1007/978-3-642-67984-1_28
Publikováno v:
Archives of Toxicology ISBN: 9783540136705
Several subpopulations of hepatocytes with increasing cell diameters were isolated, the smaller cells were attributed to the periportal area, the larger ones to the perivenous region. Profiles of total cytochrome P-450, benzphetamine N-demethylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ed8f03ac33cdd17a020cd3f68fd8902
https://doi.org/10.1007/978-3-642-69928-3_108
https://doi.org/10.1007/978-3-642-69928-3_108
Autor:
S. Bjelland, G. Volden
Publikováno v:
Current Topics in Contact Dermatitis ISBN: 9783642743016
After developing an in vitro assay system, we found that fish stomach and intestinal homogenates as well as purified fish pepsin and trypsin effect significant degradation of human epidermal keratin. The activity of trypsin and pepsin of five differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::935fef940823dbd3bdaacb1567e2ddc9
https://doi.org/10.1007/978-3-642-74299-6_88
https://doi.org/10.1007/978-3-642-74299-6_88
Publikováno v:
Intracranial Pressure VII ISBN: 9783642739897
CSF formation can be inhibited by ouabain, suggesting an involvement of transport systems dependent on sodium-potassium activated adenosine triphosphatase (Na+-K+-ATPase) (Cserr 1975). Recently, it has been found that the gastric mucosa of pig, dog a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a67ecb6304ef4f98e58674205fd41787
https://doi.org/10.1007/978-3-642-73987-3_83
https://doi.org/10.1007/978-3-642-73987-3_83
Autor:
Clement E. Furlong, Rebecca J. Richter, Lucio G. Costa, Arno G. Motulsky, Gilbert S. Omenn, Sheldon D. Murphy
Publikováno v:
Toxicology of Pesticides ISBN: 9783642709005
Paraoxon (diethyl-p-nitrophenylphosphate) is the active metabolite of parathion (diethyl-p-nitrophenylphosphorothioate), a widely used organo-phosphorus insecticide. After activation of parathion by the cytochrome P450 system, the paraoxon is hydroly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e562cad43786d58e41f5464020488cf
https://doi.org/10.1007/978-3-642-70898-5_19
https://doi.org/10.1007/978-3-642-70898-5_19
Autor:
G. Wolberg
Publikováno v:
Handbook of Experimental Pharmacology ISBN: 9783642732195
The study of the involvement of purines in lymphocyte function has been highlighted by two dramatic and unrelated discoveries. The first, the discovery in 1958 that 6-mercaptopurine (6-MP) had marked immunosuppressive properties (Schwartz et al. 1958
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7319bb0563b40b37f620206b90e5a5df
https://doi.org/10.1007/978-3-642-73217-1_24
https://doi.org/10.1007/978-3-642-73217-1_24