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Autor:
Raquel M. Schears, Kevin M Takakuwa
Publikováno v:
International Journal of Emergency Medicine
International Journal of Emergency Medicine, Vol 14, Iss 1, Pp 1-18 (2021)
International Journal of Emergency Medicine, Vol 14, Iss 1, Pp 1-18 (2021)
BackgroundCannabis is the most prevalent illegal drug used and the second most common cause of ED drug-related complaints in the USA. Recently, newer more potent strains, concentrated THC products, and consumption methods have become available.Object
Autor:
Soo Jin Wi, Ky Young Park
Publikováno v:
Journal of Plant Biology = Singmul Hakhoe Chi
Plants have great potential as photosynthetic factories to produce pharmaceutically important and commercially valuable biomedicines and industrial proteins at low cost. The U.S. Food and Drug Administration (U.S. FDA) has approved the drug Elelyso (
Autor:
Felix Lötsch, Klaus Kaczirek, Fredrik Waneck, Herbert Auer, Judith Naderer, Mirjam Groger, Tomislava Skuhala, Michael Ramharter
Publikováno v:
Parasitology Research
Cystic echinococcosis (CE) is a widespread zoonosis caused by the species complex Echinococcus granulosus. Albendazole (ABZ)—the first-line anthelminthic drug for medical treatment of CE—is metabolized in vivo to the active derivative ABZ-sulphox
Autor:
Daniel Weiss, Liangang Liu, Simon Zhou, Josephine Reyes, Nianhang Chen, Gondi Kumar, Lilia Weiss, Xiaomin Wang, Claudia Kasserra, Maria Palmisano
Publikováno v:
Cancer Chemotherapy and Pharmacology
Purpose Lenalidomide, a weak substrate of P-glycoprotein (P-gp) in vitro, is an oral anticancer drug eliminated predominantly via renal excretion as unchanged compound. The role of P-gp in lenalidomide disposition and the associated clinical relevanc
Autor:
Caroline P. Allen, Vanessa Venning
Publikováno v:
Blistering Diseases ISBN: 9783662456972
Linear immunoglobulin A (IgA) disease is an acquired autoimmune blistering condition of the skin and mucous membranes, characterised by linear deposition of IgA along the dermoepidermal basement membrane zone. In adults, drug triggers should be consi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87889dcc17add732a12ae28c4decdb0f
https://doi.org/10.1007/978-3-662-45698-9_58
https://doi.org/10.1007/978-3-662-45698-9_58
Publikováno v:
Springer Series on Biofilms ISBN: 9783642538322
Infections caused by opportunistic human fungal pathogens are very common and have shown steady increase in recent years. The typical hosts, which are prone to fungal infections, are those who possess suppressed immune systems due to conditions such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87483e1ca6d93e0ca7a6aa93442361f1
https://doi.org/10.1007/978-3-642-53833-9_4
https://doi.org/10.1007/978-3-642-53833-9_4
Publikováno v:
Current Topics in Microbiology and Immunology ISBN: 9783642402319
Tuberculosis (TB) has become a curable disease thanks to the discovery of antibiotics. However, it has remained one of the most difficult infections to treat. Most current TB regimens consist of six to nine months of daily doses of four drugs that ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe318eec4d9e78edc3bad06b0e8edca5
https://doi.org/10.1007/82_2012_279
https://doi.org/10.1007/82_2012_279
Publikováno v:
Handbook of Experimental Pharmacology ISBN: 9783642145407
Intestinal P-glycoprotein (P-gp, ABCB1) may significantly influence drug absorption and elimination. Its expression and function is highly variable, regio-selective and influenced by genetic polymorphisms, drug interactions and intestinal diseases. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1b7b958875113e152ebce51f7945a36
https://doi.org/10.1007/978-3-642-14541-4_11
https://doi.org/10.1007/978-3-642-14541-4_11
Publikováno v:
Behavioral Neuroscience of Drug Addiction ISBN: 9783642030000
The field of pharmacologic addiction treatment is expanding rapidly. While there are currently several FDA-approved medications for nicotine, alcohol, and opiate dependence, research into novel pharmacological approaches for these and additional subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::342b98b56872cfb84a2d4f52507ef528
https://doi.org/10.1007/7854_2009_29
https://doi.org/10.1007/7854_2009_29
Autor:
Bonny Blackard, Michael J. Thun
Publikováno v:
Cancer Prevention II ISBN: 9783540692966
This paper briefly reviews the pharma-cologic effects of nonsteroidal antiinflammatory drugs (NSAIDs) that influence the risks and benefits of using these drugs prophylactically for cancer. It describes the metabolism of arachidonic acid through the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc9f66b6613e8bf39e38b660fafac535
https://doi.org/10.1007/978-3-540-69297-3_20
https://doi.org/10.1007/978-3-540-69297-3_20