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Autor:
Mary C. Olmstead, Alexandra Hertz, Romain Bourdy, Yannick Goumon, Katia Befort, Dominique Filliol, Virginie Andry, Jorge E. Mendoza
Publikováno v:
European Journal of Nutrition
European Journal of Nutrition, Springer Verlag, 2021, ⟨10.1007/s00394-021-02613-0⟩
European Journal of Nutrition, 2021, 60 (8), pp.4621-4633. ⟨10.1007/s00394-021-02613-0⟩
European Journal of Nutrition, Springer Verlag, 2021, ⟨10.1007/s00394-021-02613-0⟩
European Journal of Nutrition, 2021, 60 (8), pp.4621-4633. ⟨10.1007/s00394-021-02613-0⟩
Objectives Increased availability of high-calorie palatable food in most countries has resulted in overconsumption of these foods, suggesting that excessive eating is driven by pleasure, rather than metabolic need. The behavior contributes to the ris
Publikováno v:
Cell and Tissue Research
Glial cell line–derived neurotrophic factor (GDNF) is a 134 amino acid protein belonging in the GDNF family ligands (GFLs). GDNF was originally isolated from rat glial cell lines and identified as a neurotrophic factor with the ability to promote d
Autor:
Vincent M. Carroll, Daniel Holden, Seth C. Hopkins, Kenneth S. Koblan, Robert Lew, Richard E. Carson, Cristian Constantinescu, Gerald Galluppi
Publikováno v:
Psychopharmacology
Rationale Drugs that rapidly increase dopamine levels have an increased risk of abuse. Dasotraline (DAS) is a dopamine and norepinephrine reuptake inhibitor characterized by slow oral absorption with low potential for abuse. However, it remains uncle
Autor:
Eiichiro Mori, Joachim Luginbühl, Sonia Sabate-Soler, Jens Christian Schwamborn, Silvia Bolognin, Alexander Skupin, Stefano Magni, Kaoru Kinugawa, Kamil Grzyb, Lisa M. Smits, Jay W. Shin
Publikováno v:
Cell and Tissue Research
Human stem cell-derived organoids have great potential for modelling physiological and pathological processes. They recapitulate in vitro the organization and function of a respective organ or part of an organ. Human midbrain organoids (hMOs) have be
Autor:
David Smith, Frank W. Lewis, Joanna L. Elson, David Tetard, Ilse S. Pienaar, Véronique Hubscher-Bruder, David T. Dexter, Safiya Fairooz, Jérémy Brandel, Meera Soundararajan
Publikováno v:
Archives of Toxicology
Archives of Toxicology, Springer Verlag, 2020, ⟨10.1007/s00204-020-02672-y⟩
Archives of Toxicology, Springer Verlag, 2020, ⟨10.1007/s00204-020-02672-y⟩
Ubiquitin proteasome system (UPS) impairment, excessive cellular oxidative stress, and iron dyshomeostasis are key to substantia nigra dopaminergic neuronal degeneration in Parkinson's disease (PD); however, a link between these features remains unco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff0753df8db8fd0462fcecf77f14fd15
https://shura.shu.ac.uk/26416/1/204_2020_Article_2672.pdf
https://shura.shu.ac.uk/26416/1/204_2020_Article_2672.pdf
Autor:
Hiroaki Masuzaki, Masayuki Matsushita, Masato Tsutsui, Keiko Abe, Tadashi Kaname, Chisayo Kozuka, Chitoshi Takayama, Chigusa Shimizu-Okabe
Publikováno v:
Diabetologia
Aims/hypothesis Overeating of dietary fats causes obesity in humans and rodents. Recent studies in humans and rodents have demonstrated that addiction to fats shares a common mechanism with addiction to alcohol, nicotine and narcotics in terms of a d
Autor:
Richard Wade-Martins, Marta Cherubini
Publikováno v:
Cell and Tissue Research
Preferential degeneration of dopamine neurons (DAn) in the midbrain represents the principal hallmark of Parkinson's disease (PD). It has been hypothesized that major contributors to DAn vulnerability lie in their unique cellular physiology and archi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5cc9e60b03bb8f6c54f5ed0bb52906
https://ora.ox.ac.uk/objects/uuid:db6025ad-7d2d-4ae5-bd80-6562441e2cb1
https://ora.ox.ac.uk/objects/uuid:db6025ad-7d2d-4ae5-bd80-6562441e2cb1
Autor:
Nicole Praschak-Rieder, Rupert Lanzenberger, Christoph Spindelegger, Siegfried Kasper, Matthäus Willeit
Publikováno v:
PET and SPECT in Psychiatry ISBN: 9783642403835
Seasonal fluctuations in mood, behaviour, energy level and appetite are common in humans living in temperate and polar zones. These changes are not necessarily associated with clinical symptoms; however, some people regularly experience severe change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eaccb7c507859b9a4cd5da875557409
https://doi.org/10.1007/978-3-642-40384-2_8
https://doi.org/10.1007/978-3-642-40384-2_8
Dopaminergic neurons regulate and organize numerous important behavioral processes including motor activity. Consistently, manipulation of brain dopamine concentrations changes animal activity levels. Dopamine is synthesized by several neuronal popul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::311ac39a539775f48f46a905b0ab6020
https://europepmc.org/articles/PMC5561950/
https://europepmc.org/articles/PMC5561950/
Autor:
Paul Cumming, Per Borghammer
Publikováno v:
Brain Imaging in Behavioral Neuroscience ISBN: 9783642287107
The main motor symptoms of Parkinson’s disease (PD) are linked to degeneration of the nigrostriatal dopamine (DA) fibers, especially those innervating the putamen. This degeneration can be assessed in molecular imaging studies with presynaptic trac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1384be306fa59f40af325e007906f40
https://doi.org/10.1007/7854_2011_165
https://doi.org/10.1007/7854_2011_165