Zobrazeno 1 - 10
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Autor:
David Smith, Frank W. Lewis, Joanna L. Elson, David Tetard, Ilse S. Pienaar, Véronique Hubscher-Bruder, David T. Dexter, Safiya Fairooz, Jérémy Brandel, Meera Soundararajan
Publikováno v:
Archives of Toxicology
Archives of Toxicology, Springer Verlag, 2020, ⟨10.1007/s00204-020-02672-y⟩
Archives of Toxicology, Springer Verlag, 2020, ⟨10.1007/s00204-020-02672-y⟩
Ubiquitin proteasome system (UPS) impairment, excessive cellular oxidative stress, and iron dyshomeostasis are key to substantia nigra dopaminergic neuronal degeneration in Parkinson's disease (PD); however, a link between these features remains unco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff0753df8db8fd0462fcecf77f14fd15
https://shura.shu.ac.uk/26416/1/204_2020_Article_2672.pdf
https://shura.shu.ac.uk/26416/1/204_2020_Article_2672.pdf
Publikováno v:
Behavioral Neuroscience of Attention Deficit Hyperactivity Disorder and Its Treatment ISBN: 9783642246111
The neonatal 6-OHDA-lesioned rat, coloboma mouse, DAT-KO mouse, and spontaneously hypertensive rat (SHR) models all bear a phenotypic resemblance to ADHD in that they express hyperactivity, inattention, and/or impulsivity. The models also illustrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e59b0866cb24dddd02bcf2ddc639422
https://doi.org/10.1007/7854_2011_121
https://doi.org/10.1007/7854_2011_121
Publikováno v:
Results and Problems in Cell Differentiation ISBN: 9783642144257
The gustatory system allows the brain to monitor the presence of chemicals in the oral cavity and initiate appropriate responses of acceptance or rejection. Among such chemicals are the nutrients that must be rapidly recognized and ingested for immed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1673f315e59adcd33d98ea7884d7a923
https://doi.org/10.1007/978-3-642-14426-4_7
https://doi.org/10.1007/978-3-642-14426-4_7
Publikováno v:
Topics in Medicinal Chemistry ISBN: 9783540879114
The evolution of antidepressants over the past four decades has involved the replacement of drugswith a multiplicity of effects (e.g., TCAs) by those with selective actions (i.e., SSRIs). This strategywas employed to reduce the adverse effects of TCA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a584a708673e7c89c4d9c651944a406d
https://doi.org/10.1007/7355_2007_016
https://doi.org/10.1007/7355_2007_016
Publikováno v:
Dopamine in the CNS I ISBN: 9783642627262
Initial classification of dopamine (DA) receptors into D1 and D2 subtypes on the basis of stimulatory and no/inhibitory linkage to adenylyl cyclase (AC), respectively (Spano et al 1978; Kebabian and Calne 1979), endured in substance for approximately
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0a0b816647c74959f3bfcfb3bc5cd70
https://doi.org/10.1007/978-3-642-56051-4_5
https://doi.org/10.1007/978-3-642-56051-4_5
Publikováno v:
Dopamine in the CNS II ISBN: 9783642076596
The nigrostriatal dopaminergic pathway has generally been used as an experimental model for basic investigations into the release of dopamine (DA) from central dopaminergic neurons. The release of DA from striatal nerve endings is not only dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89e1f621b89e2fc1a26126806fa0efc7
https://doi.org/10.1007/978-3-662-06765-9_2
https://doi.org/10.1007/978-3-662-06765-9_2
Autor:
A. Carlsson
Publikováno v:
Dopamine in the CNS I ISBN: 9783642627262
The history of dopamine goes back to the early part of the previous century. This compound was synthesized by Waser and Sommer (1923). Its physiological significance became evident through the discovery of dopa decarboxylase in mammalian tissue by Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98afc50139f4f2b47e6ad769213704b7
https://doi.org/10.1007/978-3-642-56051-4_2
https://doi.org/10.1007/978-3-642-56051-4_2
Publikováno v:
Crustacean Experimental Systems in Neurobiology ISBN: 9783642628603
It is now well accepted that neuromodulators play a critical role in the control of behavior (for review, see Katz 1999). These versatile compounds adjust neuronal function at every level of the nervous system, from sensory reception through central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca6a3eb21c7f82f10e24bbc91201d746
https://doi.org/10.1007/978-3-642-56092-7_2
https://doi.org/10.1007/978-3-642-56092-7_2
Autor:
S. J. Enna
Publikováno v:
Pharmacology of GABA and Glycine Neurotransmission ISBN: 9783642631917
The GABAB receptor was first identified and characterized on the basis of its sensitivity to baclofen and insensitivity to bicuculline, benzodiazepines, and other agents known to interact with the GABAA site (Bowery et al. 1980). Earlier and subseque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c86c402c05722c60205f0e5c02c1411a
https://doi.org/10.1007/978-3-642-56833-6_13
https://doi.org/10.1007/978-3-642-56833-6_13
Autor:
A. J. Cross, A. R. Green, Paul T. Francis, J. E. Steele, S. L. Lowe, G. C. Stratmann, David M. Bowen, A. W. Procter
Publikováno v:
Imaging, Cerebral Topography and Alzheimer’s Disease ISBN: 9783642756924
Cortical inhibitory neurotransmitters, neuropeptides, dopamine and probably noradrenaline are probably either not selectively or not critically affected in Alzheimer’s disease. It is, however, highly likely that shrinkage or loss of corticocortical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33c0b32e30401e9f618fbaada740c705
https://doi.org/10.1007/978-3-642-75690-0_3
https://doi.org/10.1007/978-3-642-75690-0_3