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Publikováno v:
Cytokines in Hemopoiesis, Oncology, and AIDS II ISBN: 9783540552420
In recent years many studies were devoted to transduction of foreign genes into hematopoietic precursor cells of different kinds of mammal [1]. There were also attempts to transduce genes into hematopoietic stromal cells, i.e., into endothelial cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::806da1dfcbd68188fcc1d70746f13a4e
https://doi.org/10.1007/978-3-642-48715-6_11
https://doi.org/10.1007/978-3-642-48715-6_11
Autor:
R. Lemoli, A. Tafuri, P. Bettelheim, Elihu Estey, Bayard D. Clarkson, Peter Valent, A. Deisseroth, E. Mandelli, A. Goodacre, Michael Andreeff
Publikováno v:
Acute Leukemias ISBN: 9783540539490
Human leukemia has been extensively investigated over the last 25 years regarding its cell kinetics, cytokine regulation, and molecular defects. It has been postulated that leukemic cells proliferate at variable rates, with DNA synthesis times as sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::924f43dcf40920103a6d063970bb693b
https://doi.org/10.1007/978-3-642-76591-9_17
https://doi.org/10.1007/978-3-642-76591-9_17
Autor:
H. Kirchner, J. Atzpodien, Deicher H, S. Quesada, R. Leo, P. A. Palmer, C. R. Franks, D. Peest, S. Stannat-Kießling, R. Hein, P. Evers, A. G. Schmidt
Publikováno v:
Cytokines in Hemopoiesis, Oncology, and AIDS II ISBN: 9783540552420
The median survival of patients with stage II or III multiple myeloma (MM) treated with chemotherapy is 3 years. Since the introduction of melphalan/prednisone treatment no significant improvement in this prognosis has been attained even by applying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20ad8affb4099429a1aeaa89bf325201
https://doi.org/10.1007/978-3-642-48715-6_94
https://doi.org/10.1007/978-3-642-48715-6_94
Publikováno v:
Cytokines in Hemopoiesis, Oncology, and AIDS II ISBN: 9783540552420
Granulocyte-macrophage colony-stimulating factor (GM-CSF) can now be considered a therapeutic hematopoietic growth factor since its use is becoming more and more widespread in various hematological malignancies [1–3]. However, the role of this mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54f5e196292448559ba2bcd1e02ecdca
https://doi.org/10.1007/978-3-642-48715-6_5
https://doi.org/10.1007/978-3-642-48715-6_5
Autor:
B. Gansbacher, E. Gilboa
Publikováno v:
Acute Leukemias ISBN: 9783540539490
Previously, we have shown that CMS5, a fibrosarcoma, could be induced to secrete lymphokines into the immediate surroundings of the tumor cells following transduction with the interleukin-2 (IL-2) or mouse interferon gamma (IFN-gamma) gene, resulting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48b9fffb70e4d5827075b3260166d5aa
https://doi.org/10.1007/978-3-642-76591-9_23
https://doi.org/10.1007/978-3-642-76591-9_23
Publikováno v:
Cytokines in Hemopoiesis, Oncology, and AIDS ISBN: 9783540522812
With its improved availability, interferon-gamma (IFN-γ) has become increasingly interesting for therapeutic approaches. Up to now IFN-α and s have mainly been used in clinical trials to treat severe viral infections and certain malignant diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3830fe6075433220e1fa97145c634292
https://doi.org/10.1007/978-3-642-75510-1_29
https://doi.org/10.1007/978-3-642-75510-1_29
Publikováno v:
Acute Leukemias II ISBN: 9783540509844
The myelodysplastic syndrome (MDS) is a clonal disorder of the hemopoietic stem cell resulting in multilineage cytopenias in vivo. In vitro a reduced myeloid and erythroid colony formation is observed [1, 2]. The reduced colony formation may be due t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d5fd7b5fb9908a0c1a593253246cb1b
https://doi.org/10.1007/978-3-642-74643-7_18
https://doi.org/10.1007/978-3-642-74643-7_18
Publikováno v:
Predictive Drug Testing on Human Tumor Cells ISBN: 9783642822971
Epithelial ovarian cancer is a disease which is well suited to the evaluation of in vitro tests for the individual selection of a patient’s chemotherapy, since a variety of antineoplastic drugs have significant activity in this disease (Young 1975)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78e26b3692455a741272c622b5b370c5
https://doi.org/10.1007/978-3-642-82295-7_5
https://doi.org/10.1007/978-3-642-82295-7_5
Autor:
Charles J. Sherr
Publikováno v:
Cell to Cell Signals in Mammalian Development ISBN: 9783642731440
The hematopoietic colony stimulating factors (CSFs) affect the proliferation, differentiation, and survival of progenitor cells in the bone marrow and prime mature blood cells to carry out their differentiated functions (Metcalf, 1985; Clark and Kame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c42228d703144895759956b3c7f3a63a
https://doi.org/10.1007/978-3-642-73142-6_16
https://doi.org/10.1007/978-3-642-73142-6_16
Autor:
P. Lundsgaard-Hansen, J. E. Doran
Publikováno v:
Klinische Anästhesiologie und Intensivtherapie ISBN: 9783540175902
>In recent years, two assumptions have led to a sustained interest in the role played by plasma fibronectin (Fn) in health and disease. The first is that plasma Fn serves as a critical regulator of reticuloendothelial system (RES) function; the secon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0574de8b9e80470fece2c7a675af3e7a
https://doi.org/10.1007/978-3-642-72533-3_19
https://doi.org/10.1007/978-3-642-72533-3_19