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Autor:
Jose L. Fernandez-Luna
Publikováno v:
Molecular Basis of Chronic Myeloproliferative Disorders ISBN: 9783642622717
Hematopoietic progenitor cell survival is mediated via the interaction of stimulatory and inhibitory hematopoietins (i.e., cytokines, growth factors) and their receptors. Among these, erythropoietin (EPO) is the principal growth factor that promotes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e41280b62ee995eb0dc5ab581002827
https://doi.org/10.1007/978-3-642-18738-4_9
https://doi.org/10.1007/978-3-642-18738-4_9
Publikováno v:
Lymphohaematopoietic Growth Factors in Cancer Therapy II ISBN: 9783642778032
Lymphocytes from healthy individuals are able to kill certain tumour cells and immature haematopoietic cells in vitro spontaneously. This type of cytotoxicity was described some years ago as “natural cytotoxicity” because it was present spontaneo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a8067a19e662992937b71a6b581fac6
https://doi.org/10.1007/978-3-642-77801-8_3
https://doi.org/10.1007/978-3-642-77801-8_3
Publikováno v:
Acute Leukemias ISBN: 9783540539490
The development of resistance to chemotherapeutic agents is still a major cause of treatment failure in cancer patients. The mechanisms by which drug resistance develops are poorly understood. Cyclophosphamide (CP) is widely used in the treatment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8506255e5ecb76db212b74917bd32f02
https://doi.org/10.1007/978-3-642-76591-9_11
https://doi.org/10.1007/978-3-642-76591-9_11
Publikováno v:
Cytokines in Hemopoiesis, Oncology, and AIDS II ISBN: 9783540552420
Granulocyte-macrophage colony-stimulating factor (GM-CSF) can now be considered a therapeutic hematopoietic growth factor since its use is becoming more and more widespread in various hematological malignancies [1–3]. However, the role of this mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54f5e196292448559ba2bcd1e02ecdca
https://doi.org/10.1007/978-3-642-48715-6_5
https://doi.org/10.1007/978-3-642-48715-6_5
Publikováno v:
Cytokines in Hemopoiesis, Oncology, and AIDS ISBN: 9783540522812
With its improved availability, interferon-gamma (IFN-γ) has become increasingly interesting for therapeutic approaches. Up to now IFN-α and s have mainly been used in clinical trials to treat severe viral infections and certain malignant diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3830fe6075433220e1fa97145c634292
https://doi.org/10.1007/978-3-642-75510-1_29
https://doi.org/10.1007/978-3-642-75510-1_29
Autor:
M. A. S. Moore
Publikováno v:
Leukemia ISBN: 9783642697241
Studies of myeloid leukemic cell lines and primary cultures of leukemic bone marrow have yielded information on humoral regulation of growth and differentiation of myeloid cells and have revealed specific abnormalities in regulatory control that woul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f99ebd7132ca4174411ab4f702a6941
https://doi.org/10.1007/978-3-642-69722-7_4
https://doi.org/10.1007/978-3-642-69722-7_4
Publikováno v:
Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ISBN: 9783540509677
Lymphokine-activated killer (LAK) cells are known to lyse fresh solid tumor cells in vitro [1], and clinical studies suggest that adoptive immunotherapy with LAK cells and interleukin-2 (IL-2) may be a promising approach in the treatment of solid tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40005b7a617d47ea4ceaf78cde425fc8
https://doi.org/10.1007/978-3-642-74621-5_78
https://doi.org/10.1007/978-3-642-74621-5_78
Publikováno v:
Recent Results in Cancer Research ISBN: 9783642814938
The mechanism of the antitumoral effect of levan was studied in the C57BL mice-Lewis lung carcinoma system. Modulation of host immune response and a direct inhibitory effect on tumor cells were found. Local treatment was more effective when begun ear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e558b536f3d1239b0cae996d1608ab6
https://doi.org/10.1007/978-3-642-81491-4_27
https://doi.org/10.1007/978-3-642-81491-4_27
Publikováno v:
Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ISBN: 9783540118589
Glucocorticoids are regularly employed in the therapeutic regimes of hematologic malignancies. In attempting to understand partially the therapeutic effect of these hormones, the in vitro cortisol-induced lysis of leukemic cells was studied. In previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95d854dd9b1857338fb4f7f79310d48b
https://doi.org/10.1007/978-3-642-68761-7_33
https://doi.org/10.1007/978-3-642-68761-7_33
Autor:
K. A. Foon
Publikováno v:
Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ISBN: 9783540177548
Progress had been made over the past 5 years toward the development of specific biological approaches to the treatment of cancer. The techniques of genetic engineering and mass cell culture, and improved techniques in protein and nucleic acid sequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c85be35dcbe6e623c461e380c9f2b66
https://doi.org/10.1007/978-3-642-72624-8_22
https://doi.org/10.1007/978-3-642-72624-8_22