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Publikováno v:
Recent Results in Cancer Research ISBN: 9783642544897
Sunitinib is an oral multikinase inhibitor that blocks the vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor (PDGFR) alpha and beta, c-kit, and other receptors. These attributes have proven to be efficacious
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4ad5a0f8b9ac322b7dd92bb3bf4f601
https://doi.org/10.1007/978-3-642-54490-3_9
https://doi.org/10.1007/978-3-642-54490-3_9
Autor:
Vino Daniel
Publikováno v:
Drug Discovery and Evaluation: Pharmacological Assays ISBN: 9783642277283
Drug Discovery and Evaluation: Pharmacological Assays ISBN: 9783319053912
Drug Discovery and Evaluation: Pharmacological Assays ISBN: 9783319053912
The differentiation between central and peripheral analgesic drugs is nowadays of more or less historical value. Most of the so-called peripheral analgesics possess anti-inflammatory properties and in some cases also antipyretic activity besides anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5983f69430a6bb85835ce413ac93ba54
https://doi.org/10.1007/978-3-642-27728-3_41-1
https://doi.org/10.1007/978-3-642-27728-3_41-1
Autor:
Joshua S. Hundert, Ajay K. Singh
Publikováno v:
Management of Chronic Kidney Disease ISBN: 9783642546365
A large number of patients with CKD suffer from anemia. This anemia is primarily due to iron deficiency as well as disturbances in the erythropoietin and hepcidin hormonal axes. The most recent guidelines for the management of the anemia associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa80a24b553aae57ad02be44e39eeec9
https://doi.org/10.1007/978-3-642-54637-2_15
https://doi.org/10.1007/978-3-642-54637-2_15
Publikováno v:
Proceedings of the 2012 International Conference on Applied Biotechnology (ICAB 2012) ISBN: 9783642379215
The ubiquitin-proteasome pathway has been accepted as a promising target for cancer therapy, as it plays a vital role in cell cycle, function, and survival. In this research, in silico study by molecular docking predicted that Tetrandrine(TET), a com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bcc51167e991c7c3d088c0cb0e7b138
https://doi.org/10.1007/978-3-642-37922-2_74
https://doi.org/10.1007/978-3-642-37922-2_74
Publikováno v:
Proceedings of the 2012 International Conference on Applied Biotechnology (ICAB 2012) ISBN: 9783642379246
In order to search for new α-amylase inhibitors from Chinese Yam (Dioscorea opposita Thunb.), the extracts of alkali-soluble crude polysaccharides (ACP), water-soluble crude polysaccharides (WCP), total saponins, and flavones were isolated, and thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acda9d36b00dfec0eeb98bd49be8a19c
https://doi.org/10.1007/978-3-642-37925-3_159
https://doi.org/10.1007/978-3-642-37925-3_159
Autor:
Jamie Textor
Publikováno v:
Platelet-Rich Plasma ISBN: 9783642401169
The therapeutic basis of platelet-rich plasma use in medicine is derived from the growth factor content and provisional matrix provided by the platelets themselves. This chapter briefly reviews the platelet research which led to the conceptual develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bf35172327e0983088cbf456455eb6d
https://doi.org/10.1007/978-3-642-40117-6_2
https://doi.org/10.1007/978-3-642-40117-6_2
Autor:
Hamid Namazi
To the Editor, I read with great interest an article that was written by Lange et al. This article was published in June 2013 and is about the effect of Denosumab on aneurysmal bone cyst [1].The authors showed well that Denosumab can be a new treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed3b68e6e771f50477fa6e4b712c218
https://europepmc.org/articles/PMC3804694/
https://europepmc.org/articles/PMC3804694/
Autor:
David S. Schrump
Publikováno v:
Epigenetic Therapy of Cancer ISBN: 9783642384035
Lung cancer cells and cell lines have been extensively studied for epigenetic alterations including global and gene-specific DNA hypermethylation, aberrant histone acetylation and methylation, and resultant gene expression changes. These epigenetic d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c4d79a881e56c127a430862a74ea4b5
https://doi.org/10.1007/978-3-642-38404-2_11
https://doi.org/10.1007/978-3-642-38404-2_11
Autor:
Nenad Blau, Francjan J. van Spronsen
Publikováno v:
Physician's Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases ISBN: 9783642403361
Hyperphenylalaninemia (HPA), a disorder of phenylalanine catabolism, is caused primarily by a deficiency of the hepatic phenylalanine-4-hydroxylase (PAH) or by one of the enzymes involved in its cofactor tetrahydrobiopterin (BH4) biosynthesis (GTP cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05270b4a6ef3681190647edd7de33465
https://doi.org/10.1007/978-3-642-40337-8_1
https://doi.org/10.1007/978-3-642-40337-8_1
Publikováno v:
IFMBE Proceedings ISBN: 9783642321825
M2 protein plays as an proton channel in influenza virus, and many candidates were proposed to inhibit its activity. Three new inhibitors were proposed recently by Du Q-S, et al. (2010), and their biding energy was higher than two commercial drug, Am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::341141e2905ec74e4fb195e64407672b
https://doi.org/10.1007/978-3-642-32183-2_93
https://doi.org/10.1007/978-3-642-32183-2_93