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Autor:
Vino Daniel
Publikováno v:
Drug Discovery and Evaluation: Pharmacological Assays ISBN: 9783642277283
Drug Discovery and Evaluation: Pharmacological Assays ISBN: 9783319053912
Drug Discovery and Evaluation: Pharmacological Assays ISBN: 9783319053912
The differentiation between central and peripheral analgesic drugs is nowadays of more or less historical value. Most of the so-called peripheral analgesics possess anti-inflammatory properties and in some cases also antipyretic activity besides anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5983f69430a6bb85835ce413ac93ba54
https://doi.org/10.1007/978-3-642-27728-3_41-1
https://doi.org/10.1007/978-3-642-27728-3_41-1
Publikováno v:
Proceedings of the 2012 International Conference on Applied Biotechnology (ICAB 2012) ISBN: 9783642379215
The ubiquitin-proteasome pathway has been accepted as a promising target for cancer therapy, as it plays a vital role in cell cycle, function, and survival. In this research, in silico study by molecular docking predicted that Tetrandrine(TET), a com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bcc51167e991c7c3d088c0cb0e7b138
https://doi.org/10.1007/978-3-642-37922-2_74
https://doi.org/10.1007/978-3-642-37922-2_74
Autor:
Chuan-Feng Chen, Ying-Xian Ma
Publikováno v:
Iptycenes Chemistry ISBN: 9783642328879
In 1999, Perchellet et al. (Anti-Cancer Drugs 10(8):749–766, 1999) reported a class of triptycene bisquinones containing the para-quinone moieties, and found that they could be used as the bi-functional anti-cancer drugs. These drugs could not only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65b2cd90a718f6a4540af5044699f5b3
https://doi.org/10.1007/978-3-642-32888-6_14
https://doi.org/10.1007/978-3-642-32888-6_14
Publikováno v:
IFMBE Proceedings ISBN: 9783642038990
Wound healing is a collaborative process involving a variety of cellular and matrix components which need to interact continually towards a common goal. Growth factors and cytokines are two distinct categories of signaling proteins that modulate woun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::977c2189cbd72902b7c98cbc80d30ff0
https://doi.org/10.1007/978-3-642-03900-3_49
https://doi.org/10.1007/978-3-642-03900-3_49
Autor:
Jose L. Fernandez-Luna
Publikováno v:
Molecular Basis of Chronic Myeloproliferative Disorders ISBN: 9783642622717
Hematopoietic progenitor cell survival is mediated via the interaction of stimulatory and inhibitory hematopoietins (i.e., cytokines, growth factors) and their receptors. Among these, erythropoietin (EPO) is the principal growth factor that promotes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e41280b62ee995eb0dc5ab581002827
https://doi.org/10.1007/978-3-642-18738-4_9
https://doi.org/10.1007/978-3-642-18738-4_9
Publikováno v:
Molecular Signaling and Regulation in Glial Cells ISBN: 9783642645013
Astrocytes are involved in a number of physiological and pathological processes of the CNS, in which cytokines may act both as stimulators and effectors of astrocyte functions. In vitro studies, including those presented here using highly enriched as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05e3983a020e9d4e233218c1b7f75a5d
https://doi.org/10.1007/978-3-642-60669-4_2
https://doi.org/10.1007/978-3-642-60669-4_2
Publikováno v:
Current Topics in Microbiology and Immunology ISBN: 9783642791321
The increased appreciation of nitric oxide (NO) as an important molecule in biology and medicine has been accompanied by an unprecedented interest in inhibitors of NO synthesis and NO scavengers. l-Arginine analogues (Fig. 1) have been used widely as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79cad1ef5da7d2184688b269f575e3a7
https://doi.org/10.1007/978-3-642-79130-7_5
https://doi.org/10.1007/978-3-642-79130-7_5
Autor:
J. Bereiter-Hahn, B. Keller-Stanislawski, Ana Ramirez-Bosca, C. Theilig, August Bernd, F. E. Görmar, Hans Holzmann, N. Rietbrock
Publikováno v:
Cell and Tissue Culture Models in Dermatological Research ISBN: 9783642778193
The influence of nicotine on cell differentiation was investigated. Cultures of human keratinocytes (HaCaT) were stained with an antibody against pan- keratin. They showed a more ordered keratin pattern with a nicotine concentration starting at 0.1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6efad014eddf248118c3ae5d3e4c7996
https://doi.org/10.1007/978-3-642-77817-9_35
https://doi.org/10.1007/978-3-642-77817-9_35
Publikováno v:
Lymphohaematopoietic Growth Factors in Cancer Therapy II ISBN: 9783642778032
Lymphocytes from healthy individuals are able to kill certain tumour cells and immature haematopoietic cells in vitro spontaneously. This type of cytotoxicity was described some years ago as “natural cytotoxicity” because it was present spontaneo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a8067a19e662992937b71a6b581fac6
https://doi.org/10.1007/978-3-642-77801-8_3
https://doi.org/10.1007/978-3-642-77801-8_3
Publikováno v:
Acute Leukemias ISBN: 9783540539490
The development of resistance to chemotherapeutic agents is still a major cause of treatment failure in cancer patients. The mechanisms by which drug resistance develops are poorly understood. Cyclophosphamide (CP) is widely used in the treatment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8506255e5ecb76db212b74917bd32f02
https://doi.org/10.1007/978-3-642-76591-9_11
https://doi.org/10.1007/978-3-642-76591-9_11