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pro vyhledávání: ''
Autor:
Nicolaus Kröger, Thomas Stübig
Publikováno v:
Cancer Immunology ISBN: 9783662464090
Acute lymphoblastic leukaemia (ALL) rises from lymphoid progenitors. ALL cells show vast antigens linked to normal B-cell development and may be used as targets for immunotherapy. Since CD20 is expressed in B-ALL cells, rituximab, an anti-CD20 antibo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a63216442c537f9e88a026b960f0d20
https://doi.org/10.1007/978-3-662-46410-6_6
https://doi.org/10.1007/978-3-662-46410-6_6
Autor:
Heather A. Jacene, Richard L. Wahl
Publikováno v:
Therapeutic Nuclear Medicine ISBN: 9783540367185
The rationale for the use of radioimmunotherapy (RIT) in cancer is that radiolabeled monoclonal antibodies specifically target and irradiate tumor cells while sparing normal tissues. The specific tumor targeting theoretically allows higher doses of r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a76494aef2ff584990873c939859ff7f
https://doi.org/10.1007/174_2013_943
https://doi.org/10.1007/174_2013_943
Autor:
Sebastian Eigner, Katerina Eigner Henke, Frantisek Melichar, René Leyva Montaña, Milos Beran, Denis R. Beckford Vera
Publikováno v:
Recent Results in Cancer Research ISBN: 9783642279935
The epidermal growth factor receptor (EGFR) is a rational target of anticancer therapies due to its overexpression in a variety of malignant epithelial tumors. Nevertheless, this antigen is also present in normal tissues. Consequently, monoclonal ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f60879eccc3d801627b44b0cfab5b83b
https://doi.org/10.1007/978-3-642-27994-2_16
https://doi.org/10.1007/978-3-642-27994-2_16
Autor:
J. Y. Blay, G. T. Stevenson, Noel-Jean Milpied, Veronique Leblond, N. Blanc-Brunat, Jean Louis Touraine, Jeanne L. Garnier
Publikováno v:
Immunosurveillance, Immunodeficiencies and Lymphoproliferations ISBN: 9783642626760
The treatment of post-transplant lymphomas still needs major improvements in order to put the patient in remission and to retain graft function. Chemotherapy is far too toxic in these patients. A more specific treatment such as anti-B-cell monoclonal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::187ec4cb2a7916dc442b312090cd254e
https://doi.org/10.1007/978-3-642-56352-2_14
https://doi.org/10.1007/978-3-642-56352-2_14
Autor:
H. O. McDevitt, C. I. Pearson
Publikováno v:
Current Topics in Microbiology and Immunology ISBN: 9783662097113
The immune system’s ability to distinguish between self and non-self relies on the intricate regulation of cellular responses to antigens presented by major histocompatibility complex (MHC) molecules to T cells. These responses include those of T h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd82fc8a9dee65fc0eeb2ef9a8f78799
https://doi.org/10.1007/978-3-662-09709-0_5
https://doi.org/10.1007/978-3-662-09709-0_5
Autor:
W. Weimar, C. R. Daane, N.M. van Besouw, Hubert G. M. Niesters, Carla C. Baan, B. Mochtar, A. H. M. M. Balk
Publikováno v:
Transplant International ISBN: 9783540610243
We used RT-PCR and ELISA to study the kinetics of IL-2 (Th1) and IL-4 (Th2) both on mRNA and protein level from “naive” PBMC and “primed” graft-infiltrating lymphocytes (GIL) obtained from a heart transplant recipient. For this purpose, these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::805c16f5b872e3ec08fb90e3eb971c7f
https://doi.org/10.1007/978-3-662-00818-8_61
https://doi.org/10.1007/978-3-662-00818-8_61
Autor:
I. Philip, E. Bouffet, C. Coze, G. Andreu, M. C. Favrot, D. Floret, J. Michon, M. Gaspard, C. R. Franks, S. Negrier, T. Philip, P. Cochat
Publikováno v:
Cytokines in Hemopoiesis, Oncology, and AIDS ISBN: 9783540522812
Considerable progress has been achieved in the treatment of stage IV neuroblastoma in children over 1 year of age. Induction therapy and surgery followed by vincristine, high-dose melphalan, total body irridiation, and autologous bone marrow transpla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f457fe7863020d02438e3550ce675bd6
https://doi.org/10.1007/978-3-642-75510-1_86
https://doi.org/10.1007/978-3-642-75510-1_86
Autor:
S. J. Korsmeyer, Warner C. Greene, Joel M. Depper, Thomas A. Waldmann, Warren J. Leonard, Carolyn K. Goldman, Richard J. Robb
Publikováno v:
Oncogenes in B-Cell Neoplasia ISBN: 9783642698620
A battery of antigen non-specific, genetically unrestricted factors derived from T cells have been shown to play a role in the regulation of B-cell responses (Howard and Paul 1983). One such factor designated B-cell growth factor (BCGF) appears to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8f44175b18ad4462dd11092b1d1b89d
https://doi.org/10.1007/978-3-642-69860-6_18
https://doi.org/10.1007/978-3-642-69860-6_18
Autor:
Alois Nowotny
Publikováno v:
Basic Exercises in Immunochemistry ISBN: 9783540094531
It is not possible to describe a general procedure of immunization which can be applied to many different antigens and different experimental animals. One reason for this is the wide variety of antigen materials. Another is the fact that different an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77ae109c247fca3f014f66cc9b7d09d9
https://doi.org/10.1007/978-3-642-67356-6_65
https://doi.org/10.1007/978-3-642-67356-6_65
Autor:
David L. Nelson
Publikováno v:
Immunology of the Neonate ISBN: 9783642710964
The thymic epithelium is first recognized in the human fetus near the 6th week of fetal gestation. This epithelial anlage becomes populated with lymphocytes which express T-lineage cell surface molecules during the 9th to 10th weeks, and these cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b138260a74a9be370960a4a7b9819b36
https://doi.org/10.1007/978-3-642-71094-0_11
https://doi.org/10.1007/978-3-642-71094-0_11