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Autor:
Sebastian Eigner, Katerina Eigner Henke, Frantisek Melichar, René Leyva Montaña, Milos Beran, Denis R. Beckford Vera
Publikováno v:
Recent Results in Cancer Research ISBN: 9783642279935
The epidermal growth factor receptor (EGFR) is a rational target of anticancer therapies due to its overexpression in a variety of malignant epithelial tumors. Nevertheless, this antigen is also present in normal tissues. Consequently, monoclonal ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f60879eccc3d801627b44b0cfab5b83b
https://doi.org/10.1007/978-3-642-27994-2_16
https://doi.org/10.1007/978-3-642-27994-2_16
Autor:
S. Jahn, K. Schmitt-Rau
Publikováno v:
Biologics in General Medicine ISBN: 9783540290179
Efalizumab is a humanized monoclonal antibody binding to the lymphocyte function-associated antigen (LFA-1). LFA-1 belongs to the family of β2 integrins and is expressed on the surface of T cells (CD4+ cells, Thelper cells; CD8+ cells, cytotoxic T c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6db43fa2ea2956f9558656297a66b8ed
https://doi.org/10.1007/978-3-540-29018-6_5
https://doi.org/10.1007/978-3-540-29018-6_5
Autor:
P. C. Klykken, K. L. White
Publikováno v:
Current Topics in Microbiology and Immunology ISBN: 9783642852282
Studies have been conducted in mice (B6C3F1) and rats (Sprague Dawley, Fischer 344) to investigate the adjuvancy potential of silicone mammary gel and the low molecular weight silicone fluid, octamethylcyclotetrasiloxane (D4). Dependent on the experi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::347f75a87c18d5f3afee612ef1fccfb3
https://doi.org/10.1007/978-3-642-85226-8_12
https://doi.org/10.1007/978-3-642-85226-8_12
Publikováno v:
New Trends in Allergy III ISBN: 9783642467196
The highly prevalent allergic cross-reactions are generally explained by the presence of common allergens in different allergen preparations, shared antigenic determinants present on different allergens, and/or multiple sensitizations. It is conceiva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c02e2c749aa91475d004baca20e2b2b1
https://doi.org/10.1007/978-3-642-46717-2_12
https://doi.org/10.1007/978-3-642-46717-2_12
Publikováno v:
Cytokines in Hemopoiesis, Oncology, and AIDS ISBN: 9783540522812
Nautral interleukin-2 (nIL-2) is a polypeptide which is synthesized and secreted in a nonglycosylated as well as in two glycosylated species. The lymphokine regulates growth and differentiation of lymphocytes. It is produced by T lymphocytes upon ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3de8a6fd4d9277d2c786c7c133b00bd5
https://doi.org/10.1007/978-3-642-75510-1_95
https://doi.org/10.1007/978-3-642-75510-1_95
Autor:
S. J. Korsmeyer, Warner C. Greene, Joel M. Depper, Thomas A. Waldmann, Warren J. Leonard, Carolyn K. Goldman, Richard J. Robb
Publikováno v:
Oncogenes in B-Cell Neoplasia ISBN: 9783642698620
A battery of antigen non-specific, genetically unrestricted factors derived from T cells have been shown to play a role in the regulation of B-cell responses (Howard and Paul 1983). One such factor designated B-cell growth factor (BCGF) appears to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8f44175b18ad4462dd11092b1d1b89d
https://doi.org/10.1007/978-3-642-69860-6_18
https://doi.org/10.1007/978-3-642-69860-6_18
Autor:
Ivan N. Rich
Publikováno v:
Molecular and Cellular Aspects of Erythropoietin and Erythropoiesis ISBN: 9783642726545
Erythropoietin can be released from bone marrow-derived macrophages grown in culture. Evidence is presented to show that, when unseparated and unstimulated mouse bone marrow cells are incubated on hydrophobic PTE foils for 14 days under reduced oxyge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ab457e4d5bba86a2bd208857194b186
https://doi.org/10.1007/978-3-642-72652-1_22
https://doi.org/10.1007/978-3-642-72652-1_22
Publikováno v:
Oncogenes and Growth Control ISBN: 9783540187608
Clonal expansion of resting T cells requires the sequential stimulation of two sets of glycoproteins: the T cell receptor (T3-Ti) complex and the interleukin-2 receptor (IL-2R) complex. The human T3-Ti complex is composed of two components: a polymor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9aae2cb8410ebb051bb9346feeedb21a
https://doi.org/10.1007/978-3-642-73325-3_18
https://doi.org/10.1007/978-3-642-73325-3_18
Publikováno v:
Rabies in the Tropics ISBN: 9783540138266
Antigenic differences among strains of rabies virus can be easily detected using a panel of monoclonal antibodies (MCAb) directed against the nucleocapsid (NC) and glycoprotein (GP) antigens of the virion. It is possible, using a limited panel of ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7562c3e3a743f68736693b4c6a29ac2c
https://doi.org/10.1007/978-3-642-70060-6_4
https://doi.org/10.1007/978-3-642-70060-6_4
Autor:
David L. Nelson
Publikováno v:
Immunology of the Neonate ISBN: 9783642710964
The thymic epithelium is first recognized in the human fetus near the 6th week of fetal gestation. This epithelial anlage becomes populated with lymphocytes which express T-lineage cell surface molecules during the 9th to 10th weeks, and these cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b138260a74a9be370960a4a7b9819b36
https://doi.org/10.1007/978-3-642-71094-0_11
https://doi.org/10.1007/978-3-642-71094-0_11