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Autor:
Walter Fiedler, Stefan Schwartz, Jochim Reinert, Klaus Wethmar, Matthias Stelljes, Antonia Beitzen-Heineke
Publikováno v:
Annals of Hematology
Treatment options for relapsed or refractory B-lymphoblastic leukaemia (r/r B-ALL) are limited and the prognosis of these patients remains dismal, but novel immunotherapeutic options such as the anti-CD22 antibody–drug-conjugate Inotuzumab-Ozogamic
Autor:
Mary C. Olmstead, Alexandra Hertz, Romain Bourdy, Yannick Goumon, Katia Befort, Dominique Filliol, Virginie Andry, Jorge E. Mendoza
Publikováno v:
European Journal of Nutrition
European Journal of Nutrition, Springer Verlag, 2021, ⟨10.1007/s00394-021-02613-0⟩
European Journal of Nutrition, 2021, 60 (8), pp.4621-4633. ⟨10.1007/s00394-021-02613-0⟩
European Journal of Nutrition, Springer Verlag, 2021, ⟨10.1007/s00394-021-02613-0⟩
European Journal of Nutrition, 2021, 60 (8), pp.4621-4633. ⟨10.1007/s00394-021-02613-0⟩
Objectives Increased availability of high-calorie palatable food in most countries has resulted in overconsumption of these foods, suggesting that excessive eating is driven by pleasure, rather than metabolic need. The behavior contributes to the ris
Publikováno v:
Cancer Immunology, Immunotherapy
Bruton’s tyrosine kinase (BTK) is a non-receptor kinase belonging to the Tec family of kinases. The role of BTK in B cell receptor signaling is well defined and is known to play a key role in the proliferation and survival of malignant B cells. Mor
Autor:
Martin Diener, Jasmin Ballout
Publikováno v:
Pflugers Archiv
Propionate, a metabolite from the microbial fermentation of carbohydrates, evokes a release of epithelial acetylcholine in rat caecum resulting in an increase of short-circuit current (Isc) in Ussing chamber experiments. The present experiments were
Autor:
Bruno Bueno-Silva, Marcelo A. Melo, Marcelo Faveri, Thayane Furtado Rocha, Ticiana Sidorenko de Oliveira Capote, Fernanda Coelho, João Marcos Spessoto Pingueiro, Sybele Saska, Jamil Awad Shibli
Publikováno v:
Clinical Oral Investigations
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Objective This study evaluated the metabolic activity of hydro-carbon-oxo-borate complex (HCOBc) on a multispecies subgingival biofilm as well as its effects on cytotoxicity. Materials and methods The subgingival biofilm with 32 species related to pe
Autor:
Nicolette C. Bishop, Alexandra L. Shill, Amber N. Leonard, Alice E. Thackray, David J. Stensel
Publikováno v:
European Journal of Applied Physiology
Purpose Asprosin, an orexigenic hormone that stimulates hepatic glucose release, is elevated in insulin resistance and associated with obesity. Plasma asprosin concentrations may also be related to female sex hormone levels; higher levels are reporte
Autor:
Axel Dalhoff
Publikováno v:
Infection
BackgroundSelective toxicity antibacteribiotics is considered to be due to interactions with targets either being unique to bacteria or being characterized by a dichotomy between pro- and eukaryotic pathways with high affinities of agents to bacteria
Six weeks of dynamic apnoeic training stimulates erythropoiesis but does not increase splenic volume
Publikováno v:
European Journal of Applied Physiology
Purpose This study examined the influence of dynamic apnoea training on splenic volume and haematological responses in non-breath-hold divers (BHD). Methods Eight non-BHD performed ten maximal dynamic apnoeas, four times a week for six weeks. Splenic
Publikováno v:
Cell and Tissue Research
Glial cell line–derived neurotrophic factor (GDNF) is a 134 amino acid protein belonging in the GDNF family ligands (GFLs). GDNF was originally isolated from rat glial cell lines and identified as a neurotrophic factor with the ability to promote d
Autor:
Vincent M. Carroll, Daniel Holden, Seth C. Hopkins, Kenneth S. Koblan, Robert Lew, Richard E. Carson, Cristian Constantinescu, Gerald Galluppi
Publikováno v:
Psychopharmacology
Rationale Drugs that rapidly increase dopamine levels have an increased risk of abuse. Dasotraline (DAS) is a dopamine and norepinephrine reuptake inhibitor characterized by slow oral absorption with low potential for abuse. However, it remains uncle