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Autor:
Ulrike Stein, Alexander Arnold, Erika Berg, Beate Rau, C Treese, Michael Hummel, M. von Winterfeld, Severin Daum
Publikováno v:
Clinical & Translational Oncology
Introduction The tight junction molecule Claudin 18.2 is selectively expressed in healthy and malignant gastric epithelial tissue and is a promising therapy target for high Claudin 18.2 expressing adenocarcinomas of the esophagogastric junction and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba822c13c78945e6c5883f885a614365
http://edoc.mdc-berlin.de/19016/2/19016suppl.zip
http://edoc.mdc-berlin.de/19016/2/19016suppl.zip
Autor:
Martin Janz, Frank Kroschinsky, Anne-Marie Quinson, Andreas Viardot, Paul La Rosée, Ute von Wangenheim, Jan Moritz Middeke, Norbert Schmitz, Reda Bouabdallah, Joerg Chromik, Mathias Witzens-Harig, Andreas Berk, Georg Lenz, Ute Burkard, Oliver G. Ottmann, Tae Min Kim, Seok Jin Kim, Gilles Salles
Publikováno v:
Invest New Drugs
Investigational New Drugs
Investigational New Drugs
Summary BI 836826 is a chimeric immunoglobulin G1 antibody targeting CD37, a tetraspanin transmembrane protein predominantly expressed on normal and malignant B cells. This phase I, open-label study used a modified 3 + 3 design to evaluate the safety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b5459b260bc1e380e32821bf6626ad
http://edoc.mdc-berlin.de/18813/7/18813suppl.pdf
http://edoc.mdc-berlin.de/18813/7/18813suppl.pdf
Autor:
C. A. R. Lok, W.J. van Driel, J. O.A.M. van Baal, E. S. Jordanova, K.K. Van de Vijver, F. C. Amant, Hugo M. Horlings
Publikováno v:
Virchows Archiv, 477(4), 535-544. Springer Verlag
van Baal, J O A M, Lok, C A R, Jordanova, E S, Horlings, H, van Driel, W J, Amant, F C & Van de Vijver, K K 2020, ' The effect of the peritoneal tumor microenvironment on invasion of peritoneal metastases of high-grade serous ovarian cancer and the impact of NEOADJUVANT chemotherapy ', Virchows Archiv, vol. 477, no. 4, pp. 535-544 . https://doi.org/10.1007/s00428-020-02795-8
van Baal, J O A M, Lok, C A R, Jordanova, E S, Horlings, H, van Driel, W J, Amant, F C & Van de Vijver, K K 2020, ' The effect of the peritoneal tumor microenvironment on invasion of peritoneal metastases of high-grade serous ovarian cancer and the impact of NEOADJUVANT chemotherapy ', Virchows Archiv, vol. 477, no. 4, pp. 535-544 . https://doi.org/10.1007/s00428-020-02795-8
Peritoneal metastases of high-grade serous ovarian cancer (HGSOC) are small-sized deposits with superficial growth toward the peritoneal cavity. It is unknown whether integrity of the peritoneal elastic lamina (PEL) correlates with the peritoneal tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c318cab177c23d2511b9c545025768e
https://lirias.kuleuven.be/handle/123456789/667106
https://lirias.kuleuven.be/handle/123456789/667106
Autor:
Hisashi Uhara, Naoya Yamazaki, Takuto Tokudome, Shusuke Yoshikawa, Satoshi Fukushima, Hiroshi Uchi, Arata Tsutsumida, N. Shibagaki, Yoshio Kiyohara, Ryuhei Okuyama, Y. Ito
Publikováno v:
Cancer Chemotherapy and Pharmacology
PurposeIpilimumab is designed to block cytotoxic T-lymphocyte antigen-4 to augment antitumor T cell responses. In studies of predominantly Caucasian patients with advanced melanoma, ipilimumab was associated with durable response, long-term survival
Autor:
Tilman T. Rau, Andrea Papadia, Maria Luisa Gasparri, Michael D. Mueller, Anda-Petronela Radan, Chantal A L Stämpfli
Publikováno v:
Papadia, Andrea; Gasparri, Maria Luisa; Radan, Anda-Petronela; Stämpfli, Chantal A L; Rau, Tilman; Mueller, Michael D (2018). Retrospective validation of the laparoscopic ICG SLN mapping in patients with grade 3 endometrial cancer. Journal of cancer research and clinical oncology, 144(7), pp. 1385-1393. Springer 10.1007/s00432-018-2648-y
PURPOSE To evaluate the sensitivity, negative predictive value (NPV) and false-negative (FN) rate of the near infrared (NIR) indocyanine green (ICG) sentinel lymph node (SLN) mapping in patients with poorly differentiated endometrial cancer who have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f47bae8054c07da85e5d452979b2c2c
Publikováno v:
Papadia, Andrea; Gasparri, Maria Luisa; Genoud, Sophie; Klaeser, Bernd; Mueller, Michael (2017). The combination of preoperative PET/CT and sentinel lymph node biopsy in the surgical management of early-stage cervical cancer. Journal of cancer research and clinical oncology, 143(11), pp. 2275-2281. Springer 10.1007/s00432-017-2467-6
INTRODUCTION The aim of the study was to evaluate the use of PET/CT and/or SLN mapping alone or in combination in cervical cancer patients. MATERIALS AND METHODS Data on stage IA1-IIA cervical cancer patients undergoing PET/CT and SLN mapping were re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45da8cf81d08763cf3033e5f7fdacef0
Autor:
René A. Tio, Clark J. Zeebregts, Jan-Luuk Hillebrands, Ming Kai Lam, Gooitzen M. van Dam, Jan-Cees Breek, Riemer H. J. A. Slart, Sali Al-Ansari
Publikováno v:
Molecular Imaging and Biology, 15(3), 250-261. SPRINGER
Unstable plaques may cause clinical events. Plaque destabilization results from the synergy between intraplaque angiogenesis and inflammation. Vascular endothelial growth factor (VEGF) and VEGF receptors (VEGFRs) are considered to be involved in thes
Publikováno v:
Lin, Y; Ness-Jensen, E; Hveem, K; Lagergren, J; & Lu, Y. (2015). Metabolic syndrome and esophageal and gastric cancer.. Cancer causes & control : CCC, 26(12), 1825-1834. doi: 10.1007/s10552-015-0675-4. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/280325m8
Cancer Causes and Control
Cancer Causes and Control
Background The role of the metabolic syndrome in the etiology of esophageal and gastric cancer is unclear. Methods This was a large nationwide cohort study based on data from 11 prospective population-based cohorts in Norway with long-term follow-up,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c82c6bf91b1b5ae33d7538c2881324bc
http://hdl.handle.net/11250/2483624
http://hdl.handle.net/11250/2483624
Autor:
Bodour Salhia, Katrin Pfaltz, Mafalda Trippel, Claudia Lädrach, Coya Tapia, Inti Zlobec, André Grogg, Nikola Cihoric
Publikováno v:
Breast Cancer Research and Treatment
Salhia, Bodour; Trippel, Mafalda; Pfaltz, Katrin; Cihoric, Nikola; Grogg, André; Lädrach, Claudia; Zlobec, Inti; Tapia, Coya (2015). High tumor budding stratifies breast cancer with metastatic properties. Breast cancer research and treatment, 150(2), pp. 363-371. Springer 10.1007/s10549-015-3333-3
Salhia, Bodour; Trippel, Mafalda; Pfaltz, Katrin; Cihoric, Nikola; Grogg, André; Lädrach, Claudia; Zlobec, Inti; Tapia, Coya (2015). High tumor budding stratifies breast cancer with metastatic properties. Breast cancer research and treatment, 150(2), pp. 363-371. Springer 10.1007/s10549-015-3333-3
Tumor budding refers to single or small cluster of tumor cells detached from the main tumor mass. In colon cancer high tumor budding is associated with positive lymph nodes and worse prognosis. Therefore, we investigated the value of tumor budding as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61b019dafa105db9342b8fbbc0e93e2a