Zobrazeno 1 - 10
of 167
pro vyhledávání: '"11"'
Autor:
Krzysztof Mrózek, Robert J. Mayer, Mark J. Pettenati, Jonathan E. Kolitz, Richard Stone, Kellie J. Archer, James W. Vardiman, Richard A. Larson, Joseph O. Moore, Andrew J. Carroll, Clara D. Bloomfield, Sherif S. Farag
Publikováno v:
International Journal of Oncology.
Isolated trisomy is a relatively common cytogenetic abnormality in acute myeloid leukemia (AML), but with uncertain prognostic significance. We studied a large cohort of newly diagnosed de novo AML patients karyotyped on CALGB 8461 from 1984-1999, wh
Publikováno v:
International Journal of Molecular Medicine
Long non-coding RNA (lncRNA) small nucleolar RNA host gene 11 (SNHG11) has been shown to play an important role in the development and progression of numerous types of cancer. However, to the best of our knowledge, the role of SNHG11 in prostate canc
Publikováno v:
Oncology Reports
Lysine methyltransferase 2A (KMT2A, also known as MLL) translocations (MLL-t) are frequently associated with mutations in RAS pathway genes in acute myeloid leukemia (AML). Previous findings with a mouse model showed that cooperation of MLL/AF10 with
Publikováno v:
Oncology Reports
Non-small cell lung cancer (NSCLC) accounts for >80% of lung cancer cases and is the leading cause of cancer-associated mortality worldwide. Propofol is an anesthetic drug frequently used during tumor resection. It is also known to exert inhibitory e
Autor:
Yicheng Xie, Hao Jiang, Kangli Xu, Yongda Li, Jian Shen, Renya Zhan, Yuxiang Weng, Yu Zhu, Qiang-min Xie, Thiti Samuthrat, Tianfu Sun
Publikováno v:
Molecular Medicine Reports.
Radial glia are key neural progenitors involved in the development of the central nervous system. Tyrosine-protein phosphatase non‑receptor type 11 (Shp2) is a widely expressed intracellular enzyme with multiple cellular functions. Previous studies
Publikováno v:
Molecular Medicine Reports. 13:4859-4864
Osteosarcoma is one of the most common primary malignant bone cancers in juveniles and adults. Increasingly, reports indicate that microRNAs (miRNAs) may provide novel therapeutic targets for cancer treatment. The aim of the present study was to inve
Autor:
Yuan Huang, Xiaoai Lv, Ping Huang, Jian Huang, Xiying Shao, Bei Wang, Yabing Zheng, Xiaojia Wang, Lei Shi, Zhanhong Chen
Publikováno v:
Oncology Reports. 35:683-690
MicroRNAs are emerging as critical regulators of the initiation and progression of multiple types of human cancers, including breast cancer. In the present study, the expression of miR-181b in breast cancer patient serum and breast cancer cell lines
Publikováno v:
Oncology Reports.
Cisplatin resistance is a major cause of chemotherapeutic failure in lung cancer patients. Unraveling the molecular mechanisms underlying cisplatin (CDDP) resistance is important in lung cancer therapeutics. To explore the role of Src homology phosph
Publikováno v:
Molecular Medicine Reports
8‑bromo‑7‑methoxychrysin (BrMC), a novel chrysin analog, was reported to have anti‑cancer activities. The aim of the present study was to investigate the molecular mechanism of 8‑bromo‑7‑methoxychrysin (BrMC)‑induced apoptosis via the
Autor:
Ludmila Gorunova, Lisbeth Haugom, Sverre Heim, Anne Mette Eibak, Francesca Micci, Ivar P. Gladhaug, Sven-Petter Haugvik
Publikováno v:
Oncology Reports
The pathogenesis of sporadic pancreatic neuroendocrine neoplasms (PNENs) is poorly understood. To gain insight into the genetic mechanisms underlying this tumor entity, we performed genome-wide screening of 16 surgical specimens from 15 patients with