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Publikováno v:
International Journal of Molecular Medicine
Acute kidney injury (AKI) is characterized by an abrupt deterioration of renal function. Formononetin (FOR) protects against cisplatin (CIS)‑induced AKI, and it has various potential pharmacological and biological effects, including anti‑inflamma
Publikováno v:
Molecular Medicine Reports
Eupatorium perfoliatum L. (E. perfoliatium) has been used traditionally for treating fever, malaria and inflammation-associated diseases. Eupafolin, the extract of E. perfoliatium, was also reported to suppress inflammation. The present study aimed t
Autor:
Nikolaos Ioannou, Said Abdullah Khelwatty, Helmout Modjtahedi, Satvinder Mudan, Angus G. Dalgleish, Tanzeel Khan, Alan M. Seddon
Publikováno v:
Oncology Reports
Pancreatic cancer is one of the most aggressive, heterogeneous and fatal type of human cancers for which more effective therapeutic agents are urgently needed. Here, we investigated the sensitivity of a panel of seven human pancreatic cancer cell lin
Publikováno v:
Molecular Medicine Reports
In order to improve the water solubility of the volatile oils extracted from Flos magnoliae (FM) and Centipeda minima (CM), they were prepared as a microemulsion (ME), which were then used in the development of an FM and CM volatile oil ME for the tr
Publikováno v:
International Journal of Oncology
Liver cancer is a leading cause of cancer-related mortality globally. Since hepatitis virus infections have been strongly associated with the incidence of liver cancer, studies concerning the effects of antiviral drugs on liver cancer have attracted
Autor:
Radu Vidra, Snejeana Tintari, Tudor Ciuleanu, Adina Nemes, Andrada Deac, Andreea Vidrean, Sebastian Pintea
Publikováno v:
Experimental and Therapeutic Medicine
The addition of platinum compounds to standard neoadjuvant chemotherapy (NACT) for triple-negative breast cancer (TNBC) is highly controversial. Platinum agents, such as cisplatin and carboplatin, are DNA-damaging agents which exhibit activity in bre
Publikováno v:
Biomedical Reports
The aim of the present study was to clarify the effect of recombinant human erythropoietin (EPO) and low molecular weight heparin (LMWH) on a rat model of lipopolysaccharide (LPS)-induced disseminated intravascular coagulation (DIC). Experimental DIC
Autor:
Jun Ma, Xuexi Tang, Wenjin Hao, Xiaojie Chen, Qiusheng Zheng, Zhaohai Pan, Xuejie Zhu, Defang Li
Publikováno v:
Oncology Letters
Although the reduction of oxaliplatin doses may alleviate deleterious side effects of gastrointestinal and gynecological cancer treatment, it also limits the anticancer therapeutic effects. As a high-efficient and low-priced herbal medicine ingredien
Autor:
Kazuaki Takabe, Takafumi Shima, Kazuhiro Yoshida, Jun Arima, Sang-Woong Lee, Kohei Taniguchi, Kazuhisa Uchiyama, Yosuke Inomata, Yoshihisa Tokumaru
Publikováno v:
Oncology Reports
Imatinib mesylate (imatinib) is the primary agent of choice used to treat gastrointestinal stromal tumors (GIST). However, drug resistance to imatinib poses a major obstacle to treatment efficacy. In addition, the relationship between imatinib resist
Publikováno v:
Molecular Medicine Reports
Cataract is a blinding‑caused disease and affects millions of individuals worldwide. Although conventional phacoemulsification (CPCS) has been widely used for treatment of cataract, the incidence of cataract‑caused blindness still increased year