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Publikováno v:
Molecular Medicine Reports
Perioperative neurocognitive dysfunction (PND) is a prevalent neurological complication after anesthesia and surgery. Ginkgolide B (GB) has been suggested to improve lipopolysaccharide‑induced learning and memory impairment. The present study aimed
Publikováno v:
Oncology Reports. 38:129-140
Anticancer bioactive peptide (ACBP) is extracted from normal goat spleens and exhibits antitumor activity alone and in combination with low cisplatin doses to achieve antitumor efficacy similar to higher cisplatin doses via sustained medication modes
Publikováno v:
Molecular Medicine Reports
Tangningtongluo (TNTL), a traditional Chinese medicine, has been widely used in clinics for decades in southwest China. Its pharmacological properties and underlying molecular mechanisms remain unclear. The main goal of ethnopharmacology is to identi
Autor:
Kaname Yamamoto, Masamichi Sugimoto, Mitsue Kurasawa, Keigo Yorozu, Nobuyuki Ishikura, Mieko Yanagisawa
Publikováno v:
Oncology Reports
Although bevacizumab maintenance following bevacizumab in combination with chemotherapy has demonstrated significant prolongation of progression-free survival in clinical studies in patients with ovarian cancer, the majority of the cancer cases in th
Autor:
Liping Zhai, Xu Wang
Publikováno v:
Molecular Medicine Reports
Syringaresinol-di-O-β-D-glucoside (SOG) is a phenolic compound extracted from Polygonatum sibiricum. The present study aimed to investigate the antidiabetic effect of SOG on streptozocin (STZ)-induced diabetic mice and determine the potential underl
Autor:
Keigo Yorozu, Kaname Yamamoto, Suguru Harada, Mitsue Kurasawa, Toshiki Iwai, Masamichi Sugimoto
Publikováno v:
Oncology Reports
Vascular endothelial growth factor (VEGF)-neutralizing therapy with bevacizumab has become increasingly important for treating colorectal cancer. It was demonstrated that second-line chemotherapy together with bevacizumab after disease progression (P
Autor:
Yi‑Biao Wang, Chao Sun, Rui-Sheng Jing, Kai‑Lin Li, Luan Zhang, Yan-Yan Pan, Yun Luan, Feng Kong, Zhao‑Hua Zhang
Publikováno v:
Molecular Medicine Reports. 14:1302-1308
Bronchopulmonary dysplasia (BPD) is the most common type of chronic lung disease in infancy, for which no effective therapy is currently available. The aim of the present study was to investigate the effect of treatment with bone marrow mesenchymal s
Publikováno v:
Molecular Medicine Reports. 13:3574-3580
Endoplasmic reticulum (ER) stress has been suggested to play a role in the progression of plaque vulnerability and the occurrence of acute complications of coronary atherosclerosis. Atorvastatin is known to exert pleiotropic effects on the cardiovasc
Publikováno v:
Oncology Reports.
Gastric cancer (GC) is the most lethal malignancy in the digestive system. This study investigated an antibody-nanoparticle conjugate (ANC) constructed with trastuzumab (Herceptin®) and nanoparticle albumin-bound paclitaxel (nab-paclitaxel, Abraxane
Publikováno v:
International Journal of Molecular Medicine
Constipation is a common affliction which causes discomfort and affects the quality of life of affected individuals. Naringenin (NAR), a natural flavonoid widely found in citrus fruits and tomatoes, has been reported to exhibit various pharmacologica