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Publikováno v:
International Journal of Oncology
Liver cancer is a leading cause of cancer-related mortality globally. Since hepatitis virus infections have been strongly associated with the incidence of liver cancer, studies concerning the effects of antiviral drugs on liver cancer have attracted
Autor:
Mieko Yanagisawa, Koh Furugaki, Kaname Yamamoto, Masamichi Sugimoto, Mitsue Kurasawa, Keigo Yorozu, Nobuyuki Ishikura, Chinami Masuda, Toshiki Iwai
Publikováno v:
International Journal of Oncology
Erlotinib, an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), shows superior efficacy in patients with non-small cell lung cancer (NSCLC) harboring activating EGFR mutations (EGFR Mut+). However, almost all tumors eventually
Autor:
Jin Park, Seol Hwa Shin, Si Yeol Song, Jung Jin Hwang, Seung-Mo Hong, Eun Jin Ju, Seong-Yun Jeong, Shun'ich Kuroda, Eun Kyung Choi, Eun Jeong Ko, Joohee Jung, Kyoung Jin Lee, Jung Shin Lee, Seok Soon Park
Publikováno v:
Oncology Reports. 38:2259-2266
The incidence of hepatocellular carcinoma (HCC) has continued to increase worldwide, and advanced HCC is difficult to treat using the currently available therapeutics. Chemoradiotherapy with cisplatin (cis-diamminedichloroplatinum, CDDP) is expected
Publikováno v:
Molecular Medicine Reports
Tangningtongluo (TNTL), a traditional Chinese medicine, has been widely used in clinics for decades in southwest China. Its pharmacological properties and underlying molecular mechanisms remain unclear. The main goal of ethnopharmacology is to identi
Autor:
Kaname Yamamoto, Masamichi Sugimoto, Mitsue Kurasawa, Keigo Yorozu, Nobuyuki Ishikura, Mieko Yanagisawa
Publikováno v:
Oncology Reports
Although bevacizumab maintenance following bevacizumab in combination with chemotherapy has demonstrated significant prolongation of progression-free survival in clinical studies in patients with ovarian cancer, the majority of the cancer cases in th
Autor:
Chenyao Zhu, Zhang Yu, Hai-Yan Xie, Bo Wang, Lei Cao, Ning Xia, Ke-Ke Hao, Feng Liu, Guo-Jun Lu
Publikováno v:
Oncology Reports.
Lung cancer nanotherapeutics aim to overcome the limitations of conventional therapeutic methods. In the present study, a self‑assembled amphiphilic prodrug‑based nanocarrier delivery system was developed that exhibited high therapeutic efficienc
Publikováno v:
Oncology Reports.
Liver cancer is one of the most devastating types of cancer worldwide. Despite years of improvements in treatment, the prognosis of patients with this type of malignancy remains poor due to frequent recurrence and metastasis after surgical resection.
Autor:
Keigo Yorozu, Kaname Yamamoto, Suguru Harada, Mitsue Kurasawa, Toshiki Iwai, Masamichi Sugimoto
Publikováno v:
Oncology Reports
Vascular endothelial growth factor (VEGF)-neutralizing therapy with bevacizumab has become increasingly important for treating colorectal cancer. It was demonstrated that second-line chemotherapy together with bevacizumab after disease progression (P
Publikováno v:
International Journal of Oncology. 48:2359-2366
Treatment of breast cancer, the second leading cause of female deaths worldwide, with classical drugs is often accompanied by treatment failure and relapse of disease condition. Development of chemoresistance and drug toxicity compels compromising th
Autor:
Hironori Aoyama, Hidekatsu Wakizaka, Takako Furukawa, Yasuhisa Fujibayashi, Tsuneo Saga, Ming-Rong Zhang, Naoya Adachi, Yukie Yoshii
Publikováno v:
International Journal of Oncology. 48:1477-1484
Colon cancer is one of the leading causes of cancer death worldwide. Adjuvant chemotherapy following primary surgical treatment is suggested to be beneficial in eradicating invisible disseminated small tumors in colon cancer; however, an effective dr