Zobrazeno 1 - 10
of 407
pro vyhledávání: '"11"'
Publikováno v:
Molecular Medicine Reports
The present study aimed to investigate the potential effects of growth differentiation factor 11 (GDF11) on isoproterenol (ISO)‑induced heart failure (HF) and identify the underlying molecular mechanisms. A rat model of HF was induced in vivo by in
Autor:
Jimin Yang, Jae Yeon Jeong, Eun Ju Lee, Woo Jean Kim, Hyoung Oh Jun, Kyeong Won Lee, Sae Won Lee
Publikováno v:
Oncology Reports. 34:2745-2751
Low oxygen or hypoxia can be observed in the central region of solid tumors. Hypoxia is a strong stimulus for new blood vessel formation or angiogenesis, which is essential for tumor growth and progression. Fibroblast growth factor 11 (FGF11) is an i
Publikováno v:
Oncology Reports. 34:1415-1423
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, mainly due to its high rates of postoperative recurrence and metastasis. Moreover, there is no widely accepted prognostic marker of recurrence. Therefore, the aim of
Autor:
Hiroshige Hibasami, Hirotaka Katsuzaki, Yayoi Yamada, Hiroyuki Moteki, Takashi Komiya, Kunio Imai
Publikováno v:
Oncology Reports.
Hot water soluble (HWS)-sesquiterpenes [anhydroperoxycostunolide and 3-oxo-eudesma-1,4(15),11(13)triene-12,6alpha-olide] were purified from Laurel (Laurus nobilis L.) and identified by Mass, and 1H- and 13C-NMR. These HWS-sesquiterpenes displayed str
Autor:
Atsumi Sano, Michio Nakamura, Takafumi Sangai, Takahiro Hasebe, Hiroyuki Maeda, Atsushi Ochiai
Publikováno v:
International Journal of Oncology.
Expression of human kallikrein 11 (hK11), secreted as a trypsin-like serine protease, is related to the prognosis of some human cancers, but its physiological functions in the steps of cancer progression are still unknown. In order to elucidate the e
Autor:
Ayumi Yoshizaki, Kazuyuki Yamazumi, Toshiyuki Nakayama, Ichiro Sekine, Mitsuru Taba, Yuichi Yakata
Publikováno v:
International Journal of Oncology.
Previous investigations have shown that interleukin (IL)-11/IL-11 receptor alpha-chain (IL-11Ralpha), a member of the PI3K, MAPK and JAK-STAT activating family of cytokines/receptors, correlates with the regulation of tumor progression. In this study
Autor:
Krzysztof Mrózek, Robert J. Mayer, Mark J. Pettenati, Jonathan E. Kolitz, Richard Stone, Kellie J. Archer, James W. Vardiman, Richard A. Larson, Joseph O. Moore, Andrew J. Carroll, Clara D. Bloomfield, Sherif S. Farag
Publikováno v:
International Journal of Oncology.
Isolated trisomy is a relatively common cytogenetic abnormality in acute myeloid leukemia (AML), but with uncertain prognostic significance. We studied a large cohort of newly diagnosed de novo AML patients karyotyped on CALGB 8461 from 1984-1999, wh
Publikováno v:
Oncology Reports.
Arsenic trioxide (As 2 O 3 ) has been used as an effective chemotherapy agent for some human cancer, such as acute promyelocytic leukemia. We have demonstrated that low level of As 2 O 3 relatively selectively inhibited growth of the solid tumor MGC-
Publikováno v:
Oncology Reports
Lysine methyltransferase 2A (KMT2A, also known as MLL) translocations (MLL-t) are frequently associated with mutations in RAS pathway genes in acute myeloid leukemia (AML). Previous findings with a mouse model showed that cooperation of MLL/AF10 with
Autor:
Rong Wang, Keliang Huang
Publikováno v:
Molecular Medicine Reports
CD4+ regulatory T (Treg) cells are associated with immune tolerance and antitumor immunosuppression. The aim of the present study was to investigate the role and molecular mechanism of C‑C motif chemokine ligand 11 (CCL11) in the regulation of Treg