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Publikováno v:
Molecular Medicine Reports. 25
In recent years, researchers have found that epigenetics plays an important role in the occurrence and development of hepatocellular carcinoma (HCC). DNA methylation is involved in the proliferation and metastasis of HCC. However, the junctophilin 3
Autor:
Gongjun, Wang, Libin, Sun, Shasha, Wang, Jing, Guo, Ruoxi, Xiao, Wenqian, Li, Weiwei, Qi, Wensheng, Qiu
Publikováno v:
Molecular Medicine Reports. 25
Ferroptosis is a form of programmed cell death that participates in diverse physiological processes. Increasing evidence suggests that long noncoding RNAs (lncRNAs) regulate ferroptosis in tumors, including stomach adenocarcinoma (STAD). In the prese
Autor:
Jingbo Liu, Yaguang Weng, Ge Yang, Shengjie Huang, Ou Jiang, Jing Zhu, Daiqiong Lin, Xianyong Li
Publikováno v:
Oncology Reports
The biological functions of circular RNAs in liver tumorigenesis have been well demonstrated by a number of studies. Nevertheless, to the best of our knowledge, the role and mechanism of action of hsa_circ_0008537 (circ_0008537) in liver cancer patho
Publikováno v:
Oncology Reports
Cell division cycle-associated 5 (CDCA5) can regulate cell cycle-related proteins to promote the proliferation of cancer cells. The purpose of the present study was to investigate the expression level of CDCA5 in prostate cancer (PCa) and its effect
Autor:
Suoyi Huang, Pengya Wei, Zhongwei Zhang, Xueping Feng, Juan Xiao, Wei Liang, Bo Ling, Bingkui Cen, Guangbin Ye, Hong Wei, Songbo Li, Wei Huang
Publikováno v:
Oncology Reports
As a potential oncogene, nucleolar and spindle‑associated protein 1 (NUSAP1) is involved in the regulation of tumor cell proliferation, metastasis and drug resistance. However, the role of NUSAP1 in non‑small cell lung cancer (NSCLC) remains uncl
Autor:
Xiaohong Xue, Pei Lu, Wenjing Diao, Yuankui Cao, Jun Li, Hua Feng, Caiying Zhu, Yu Song, Qisang Guo
Publikováno v:
Molecular Medicine Reports
Tripartite motif‑containing (TRIM) 14 is a protein of the TRIM family. Studies have indicated that TRIM14 may be used as an oncogene in tumor cells, such as osteosarcoma, non‑small cell lung cancer and breast cancer through different pathways. Ho
Publikováno v:
Oncology Reports
Glioblastoma (GBM) is one of the most prevalent and aggressive central nervous tumors with high mobility and mortality. The prognosis of patients with GBM is poor. It is therefore essential to explore the therapeutic strategies for the treatment of G
Publikováno v:
Molecular Medicine Reports
Sepsis is a serious clinical condition characterized by systemic inflammation. The long noncoding RNA (lncRNA) highly upregulated in liver cancer (HULC) was validated to partake in the development of sepsis. The present study aimed to investigate the
Publikováno v:
Molecular Medicine Reports
The present study aimed to explore the biological functions and molecular mechanisms of the long non‑coding RNA VIM antisense RNA 1 (VIM‑AS1) in gastric cancer (GC). The expression of VIM‑AS1 was analyzed in tissues from patients with GC and GC
Autor:
Masahiro Shibata, Ikumi Soeda, Yasuhiro Kodera, Takahiro Inaishi, Takahiro Ichikawa, Masamichi Hayashi, Yuko Takano, Dai Takeuchi, Nobuyuki Tsunoda, Mitsuro Kanda, Toyone Kikumori
Publikováno v:
Oncology Reports. 47
The platelet isoform of phosphofructokinase (PFKP) is one of the key enzymes in the glycolytic pathway. PFKP is highly expressed in several cancers, and it has been reported to be involved in the progression of cancer cells. However, its oncological