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Autor:
Jingbo Liu, Yaguang Weng, Ge Yang, Shengjie Huang, Ou Jiang, Jing Zhu, Daiqiong Lin, Xianyong Li
Publikováno v:
Oncology Reports
The biological functions of circular RNAs in liver tumorigenesis have been well demonstrated by a number of studies. Nevertheless, to the best of our knowledge, the role and mechanism of action of hsa_circ_0008537 (circ_0008537) in liver cancer patho
Publikováno v:
Oncology Reports
Cell division cycle-associated 5 (CDCA5) can regulate cell cycle-related proteins to promote the proliferation of cancer cells. The purpose of the present study was to investigate the expression level of CDCA5 in prostate cancer (PCa) and its effect
Autor:
Xiaohong Xue, Pei Lu, Wenjing Diao, Yuankui Cao, Jun Li, Hua Feng, Caiying Zhu, Yu Song, Qisang Guo
Publikováno v:
Molecular Medicine Reports
Tripartite motif‑containing (TRIM) 14 is a protein of the TRIM family. Studies have indicated that TRIM14 may be used as an oncogene in tumor cells, such as osteosarcoma, non‑small cell lung cancer and breast cancer through different pathways. Ho
Autor:
Pedro Cortes‑Reynosa, Eduardo Perez Salazar, Irma Elizalde‑Acosta, Rocio Thompson‑Bonilla, Javier Ramírez‑Ricardo, Carlos Manuel Ortiz Mendoza, Elia Martínez‑Baeza, Analy Herrera‑Torres, Fernando Breton‑Mora, Elizabeth Leal‑Orta
Publikováno v:
Molecular Medicine Reports
Triple negative breast cancer (TNBC) is a breast cancer subtype associated with high rates of metastasis, heterogeneity, drug resistance and a poor prognosis. Extracellular vesicles (EVs) are vesicles of endosomal and plasma membrane origin, and are
Publikováno v:
Molecular Medicine Reports. 22:2085-2092
Pancreatic cancer is a fatal disease with a high mortality rate and poor prognosis worldwide. The aberrant expression of microRNAs (miRs) is associated with cancer development and progression. The present study aimed to evaluate the functional role o
Publikováno v:
International Journal of Oncology
Breast cancer is the most common malignant tumor affecting women worldwide and is divided into the following subtypes: Luminal A, Luminal B, HER-2 overexpression and triple-negative breast cancer (TNBC). TNBC accounts for approximately 15-20% of all
Autor:
Fei Guo, Jinping Gao, Ye Yan, Guoyan Liu, Fei Teng, Yingmei Wang, Meiyue Li, Fengxia Xue, Kai Zhang, Lei Cui, Yanfang Zhang, Chao Gao, Wenyan Tian
Publikováno v:
International Journal of Oncology
Ovarian cancer is the most lethal gynecological tumor, and the 5-year survival rate is only ~40%. The poor survival rate is due to cancer diagnosis at an advanced stage, when the tumor has metastasized. A better understanding of the molecular pathoge
Autor:
Yunlei Zhang, Liangliang Xiang, Yan Zhou, Tengyang Ni, Yanqing Liu, Ishikawa Shintaro, Haibo Wang, Weimin Wang, Feng Jin, Jianliang Deng
Publikováno v:
Oncology Reports
Protein/nucleic acid deglycase DJ‑1 (DJ‑1) is a 20‑kDa conserved protein, which belongs to the DJ‑1/ThiJ/Pfp Ⅰ protein superfamily. Immunohistochemistry was performed to investigate the expression of DJ‑1 in a colorectal cancer (CRC) tiss
Autor:
Masahiro Shibata, Ikumi Soeda, Yasuhiro Kodera, Takahiro Inaishi, Takahiro Ichikawa, Masamichi Hayashi, Yuko Takano, Dai Takeuchi, Nobuyuki Tsunoda, Mitsuro Kanda, Toyone Kikumori
Publikováno v:
Oncology Reports. 47
The platelet isoform of phosphofructokinase (PFKP) is one of the key enzymes in the glycolytic pathway. PFKP is highly expressed in several cancers, and it has been reported to be involved in the progression of cancer cells. However, its oncological
Autor:
Enhua Wang, Yijun Zhang, Shumei Yan, Jiang-Bo Zhang, Yong Li, Yuanzhong Yang, Yuhua Huang, Yan Li, Pengcheng Li, Yuan Luo
Publikováno v:
Molecular Medicine Reports
Inhibin βA (INHBA) serves a prognostic and tumor-promoting role in numerous types of cancer. The present study aimed to determine the clinical significance of INHBA in non-small cell lung cancer (NSCLC) and the mechanisms underlying its potential tu