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Publikováno v:
International Journal of Oncology
Breast cancer is the most common malignant tumor affecting women worldwide and is divided into the following subtypes: Luminal A, Luminal B, HER-2 overexpression and triple-negative breast cancer (TNBC). TNBC accounts for approximately 15-20% of all
Autor:
Yunlei Zhang, Liangliang Xiang, Yan Zhou, Tengyang Ni, Yanqing Liu, Ishikawa Shintaro, Haibo Wang, Weimin Wang, Feng Jin, Jianliang Deng
Publikováno v:
Oncology Reports
Protein/nucleic acid deglycase DJ‑1 (DJ‑1) is a 20‑kDa conserved protein, which belongs to the DJ‑1/ThiJ/Pfp Ⅰ protein superfamily. Immunohistochemistry was performed to investigate the expression of DJ‑1 in a colorectal cancer (CRC) tiss
Publikováno v:
Molecular Medicine Reports
Mounting evidence has indicated that circular RNAs (circRNAs) serve essential roles in the tumorigenesis and development of various types of cancer. However, the biological functions and the underlying mechanisms of circRNAs in breast cancer (BC) rem
Publikováno v:
Molecular Medicine Reports
Osteosarcoma (OS) is a malignant disease with high morbidity and mortality rates in children and adolescents. Evidence has indicated that long non-coding RNAs (lncRNAs) may serve important roles in human cancer progression, including OS. In the prese
Autor:
Shi‑Quan Liu, Jin‑Xiu Zhang, Si‑Man Li, Zhe Ye, Ye Zhu, Jie‑An Huang, Peng Peng, Lan Lin, Meng‑Bin Qin, Qian Song, Li‑Hua Xie
Publikováno v:
Oncology Reports
Tricellulin is a tight‑junction transmembrane protein that regulates cell‑cell interactions. Altered tricellulin expression could promote tumor cell invasions and metastasis in human cancers. The present study assessed tricellulin expression in c
Autor:
Wen Jun Wei, Tian Liao, Zhong Wu Lu, Jun Xiang, Qinghai Ji, Duo Wen, Yu Wang, Li Tao Han, Yu-Long Wang
Publikováno v:
Oncology Reports
Endeavors towards identifying key molecular markers for early diagnosis and treatment are driving the clinical study of papillary thyroid carcinoma (PTC). Recent studies have indicated that protein phosphatase, Mg2+/Mn2+ dependent, 1D (PPM1D) exerts
Publikováno v:
Oncology Reports.
Cholangiocarcinoma is an aggressive malignancy with high mortality, and effective therapeutic agents for this cancer are limited. Cyclin‑dependent kinase (CDK) pathways are therapeutic targets for various types of cancers; however, their involvemen
Publikováno v:
Oncology Reports.
Cancer‑associated fibroblasts (CAFs) are known to be essential in cancer initiation and development. However, the role of CAFs in promoting ovarian cancer (OC) invasion remains to be fully elucidated. To address this in the present study, 49 clinic
Autor:
Haiying Jiang, Deyun Feng, Yang Xiong, Xiaozhou Li, Fang Huang, Xiangyang Zhang, Zhi Chen, Wei Chen
Publikováno v:
International Journal of Oncology
Lymph node metastasis in patients with urinary bladder cancer (UBC) is always associated with poor prognosis and is the determinant for tumor staging and the development of treatment regimens; however, its underlying mechanisms remain to be studied.
Autor:
Jing Quan, Xiang Pan, Yongqing Lai, Shangqi Yang, Yun Chen, Xiangming Mao, Jia Hu, Lu Jin, Yifan Li, Yaoting Gui, Tao He
Publikováno v:
Molecular Medicine Reports. 16:7072-7079
Renal cell carcinoma (RCC) is the most common type of kidney cancer and the prognosis of metastatic RCC remains poor, with a high rate of recurrence and mortality. Long non‑coding RNA (lncRNA) is a class of RNA which serves important roles in multi