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Publikováno v:
Experimental and Therapeutic Medicine.
Hyperglycemia-induced oxidative stress and inflammation are hallmarks of liver damage in diabetes mellitus. Accumulating evidence has demonstrated that Pluchea indica leaf ethanol extract (PILE) possesses strong antioxidant and anti-inflammatory prop
Autor:
Yasuyoshi Miyata, Hideki Sakai, Asato Otsubo, Tomohiro Matsuo, Yuichiro Nakamura, Tsutomu Yuno, Yuta Mukae, Kensuke Mitsunari, Kyohei Araki, Kojiro Ohba
Publikováno v:
Oncology Letters
c-Met is a receptor tyrosine kinase that binds a specific ligand, namely hepatocyte growth factor (HGF). The HGF/c-Met system is important for malignant aggressiveness in various types of cancer, including bladder cancer (BC). However, although phosp
Autor:
Ovidiu Gabriel Bratu, Camelia Cristina Diaconu, Ana Maria Alexandra Stănescu, Ovidiu Fratila, Dan Liviu Dorel Mischianu, Arsenie Dan Spinu, Simona Bungau, Roxana Bohiltea
Publikováno v:
Exp Ther Med
Botulinum toxin is a substance produced by Clostridium Botulinum and is responsible for human botulism. This substance is a poison, a neurotoxin, but used in limited quantities it can be a cure for some diseases. It is well connected to a large varie
Autor:
Noelia Puente‑Moncada, Maria Turos‑Cabal, Carmen Rodríguez, Cristina Duarte‑Olivenza, Ana M. Sánchez‑Sánchez, Federico Herrera, Jezabel Rodriguez‑Blanco, Isaac Antolín, Vanesa Martín
Publikováno v:
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
The FMS‑like tyrosine kinase 3 internal tandem duplication (FLT3‑ITD) mutation represents the most frequent genetic alteration in acute myeloid leukemia (AML) and is associated with poor prognosis. The mutation promotes cancer cell survival and p
Autor:
Yuichi Ohnishi, Hirohito Kubo, Hiroyuki Hamada, Tsukasa Sakamoto, Li Zhengguang, Hiroki Yasui, Masahiro Nakajima
Publikováno v:
Oncol Lett
Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer. OSCC cells are highly invasive, a characteristic that involves epithelial-mesenchymal transition (EMT); the conversion of immotile epithelial cells into motile mesenchymal ce
Publikováno v:
Molecular Medicine Reports
Long intergenic non-coding RNAs (lincRNAs) are long non‑coding transcripts from the intergenic regions of annotated protein‑coding genes. lincRNA cyclooxygenase 2 (Cox2) is an early‑primary response gene regulated by the NF‑κB signaling path
Autor:
Roman Fukui, Masahiko Aoki, Kazuki Hasegawa, Tomoyuki Oyama, Yoichiro Hosokawa, Kazuki Abe, Wataru Kobayashi
Publikováno v:
Oncology Letters
The current study aimed to evaluate the relationship between 18F-fluorodeoxyglucose positron emission tomography with computed tomography (FDG-PET-CT) standardized uptake value (SUV) [pre-treatment SUV (pre-SUV) and post-treatment SUV (post-SUV)] and
Publikováno v:
International Journal of Oncology.
Bone morphogenetic proteins (BMP) are pluripotent molecules, co‑ordinating cellular functions from early embryonic and postnatal development to tissue repair, regeneration and homeostasis. They are also involved in tumourigenesis, disease progressi
Autor:
Liping Hou, Hailong Tang, Yan Yu, Shan Gao, Guangxun Gao, Yaping Zhao, Zhiqiang Tian, Li Xu, Xi Cen, Guang Li, Shuchun Yu, Huafeng Zhu, Juan Feng, Li Yang
Publikováno v:
International Journal of Molecular Medicine
The emergence of new drugs is a major feature of the treatment history of multiple myeloma (MM), which also reflects the current incurability of MM. As a unique member of cyclin dependent kinase (CDK) family, CDK5 participates in numerous tumorigenic
Autor:
Daisuke Motoyama, Atsushi Otsuka, Hiromitsu Watanabe, Keita Tamura, Takayuki Sugiyama, Hideaki Miyake, Toshiki Ito, Yuto Matsushita
Publikováno v:
Molecular and Clinical Oncology.
The aim of the present study was to investigate the impact of the combined use of corticosteroid on adverse events (AEs) induced by enzalutamide (Enz) in patients with metastatic castration-resistant prostate cancer (mCRPC). The cohort of the present