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Publikováno v:
Molecular Medicine Reports
Cataract is a blinding‑caused disease and affects millions of individuals worldwide. Although conventional phacoemulsification (CPCS) has been widely used for treatment of cataract, the incidence of cataract‑caused blindness still increased year
Autor:
Shuangyue Liu, Dongyan Bao, Tao Xu, Tingting Ma, Yang Di, Li Yu, Yan Wang, Donghao Qu, Yuan Tian, Aimei Wang, Yuhan Lin
Publikováno v:
International Journal of Molecular Medicine
Cisplatin (CDDP) is widely used in clinical settings for the treatment of various cancers. However, ototoxicity is a major side effect of CDDP, and there is an associated risk of irreversible hearing loss. We previously demonstrated that CDDP could i
Publikováno v:
International Journal of Molecular Medicine
Simvastatin is effective in the treatment of osteoporosis, partly through the inhibition of the adipogenesis of bone-marrow derived mesenchymal stem cells (BMSCs). The present study focused on the mechanisms responsible for the inhibitory effects of
Publikováno v:
Oncology Reports
As the major component of the tumor matrix, collagen greatly influences tumor invasion and prognosis. The present study compared the remodeling of collagen and collagenase in 56 patients with colorectal cancer (CRC) using Sirius red stain and immunoh
Autor:
Noelia Puente‑Moncada, Maria Turos‑Cabal, Carmen Rodríguez, Cristina Duarte‑Olivenza, Ana M. Sánchez‑Sánchez, Federico Herrera, Jezabel Rodriguez‑Blanco, Isaac Antolín, Vanesa Martín
Publikováno v:
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
The FMS‑like tyrosine kinase 3 internal tandem duplication (FLT3‑ITD) mutation represents the most frequent genetic alteration in acute myeloid leukemia (AML) and is associated with poor prognosis. The mutation promotes cancer cell survival and p
Publikováno v:
Molecular Medicine Reports
Long intergenic non-coding RNAs (lincRNAs) are long non‑coding transcripts from the intergenic regions of annotated protein‑coding genes. lincRNA cyclooxygenase 2 (Cox2) is an early‑primary response gene regulated by the NF‑κB signaling path
Autor:
Feng Zhang, Sun Dongdong, Yuehua Shi, Ye Yang, Jie Qian, Xiaoyan Liu, Yan Hu, Li Jiang, Bei-Bei Jia, Qinfen Zhang
Publikováno v:
Molecular Medicine Reports
Placental structural abnormalities and dysfunction in those with gestational diabetes mellitus (GDM) can lead to increased placental permeability, which is in turn related to a poorer maternal and fetal prognosis. The present study sought to assess w
Publikováno v:
International Journal of Oncology
Carcinoma-associated fibroblasts (CAFs) secrete factors that increase the expression and/or activities of proteins in breast cancer cells and induce resistance to anti-estrogens, such as fulvestrant. A major factor is interleukin-6 (IL-6). This study
Autor:
Rui Li, Lianxin Wang
Publikováno v:
Molecular Medicine Reports
Influenza virus A (IVA) is one of the predominant causative agents of the seasonal flu and has become an important cause of morbidity worldwide. Great efforts have been paid to develop vaccines against IVA. However, due to antigenic drift in influenz
Publikováno v:
Molecular Medicine Reports
Low molecular weight heparin (LMWH) has a structure similar to heparan sulfate, which exerts anti-inflammatory effects via inhibiting elastase (Ela) activity. Release of Ela along the glomerular capillary wall may induce glomerular injury and protein