Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jacek Koronacki"'
Publikováno v:
Bioinformatics and Biology Insights, Vol 2010, Iss 4, Pp 137-146 (2010)
Externí odkaz:
https://doaj.org/article/175956a4323a44fa992faba8f0bb61f8
Autor:
Marcin Kierczak, Krzysztof Ginalski, Michał Dramiński, Jacek Koronacki, Witold Rudnicki, Jan Komorowski
Publikováno v:
Bioinformatics and Biology Insights, Vol 2009, Iss 3, Pp 109-127 (2009)
Reverse transcriptase (RT) is a viral enzyme crucial for HIV-1 replication. Currently, 12 drugs are targeted against the RT. The low fidelity of the RT-mediated transcription leads to the quick accumulation of drug-resistance mutations. The sequence-
Externí odkaz:
https://doaj.org/article/934494f5f17f4667bfbb68ab2f8dd165
Publikováno v:
Bioinformatics and Biology Insights, Vol 4 (2010)
Motivation Despite more than two decades of research, HIV resistance to drugs remains a serious obstacle in developing efficient AIDS treatments. Several computational methods have been developed to predict resistance level from the sequence of viral
Externí odkaz:
https://doaj.org/article/19db0373fa654a7bb05f128ae87632d5
Publikováno v:
Bioinformatics and Biology Insights, Vol 4 (2010)
Bioinformatics and Biology Insights, Vol 2010, Iss 4, Pp 137-146 (2010)
Bioinformatics and Biology Insights
Bioinformatics and Biology Insights, Vol 2010, Iss 4, Pp 137-146 (2010)
Bioinformatics and Biology Insights
Motivation Despite more than two decades of research, HIV resistance to drugs remains a serious obstacle in developing efficient AIDS treatments. Several computational methods have been developed to predict resistance level from the sequence of viral