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Autor:
Srinivas Sankaranarayanan, Mukul Vij
Publikováno v:
Pediatric and Developmental Pathology. 25:207-212
Whole-exome sequencing studies have recently identified novel genes implicated in normal- or low-GGT pediatric cholestasis including ubiquitin-specific peptidase 53 ( USP53). We identified novel biallelic mutations in the USP53 gene in a 7-month-old
Publikováno v:
Journal of Oncology Pharmacy Practice. 28:703-709
Introduction Capecitabine is an orally administered prodrug that converts preferentially to 5-fluorouracil within tumors, resulting in enhanced concentrations of 5-fluorouracil in tumor tissue. The use of capecitabine has shown efficacy in the metast
Publikováno v:
Tropical Doctor. 52:134-138
Spirochaetes comprise a heterogenous group of gram negative, motile, spiral shaped bacteria. Some of these pathogens are known to cause numerous human diseases such as Lyme disease, relapsing fever, syphilis and leptospirosis. However, intestinal spi
Publikováno v:
Human & Experimental Toxicology. 40:S646-S653
Objective Cytochrome P450 3A5 (CYP3A5) is a highly polymorphic gene and the encoded protein variants differ in catalytic activity, leading to inter-individual variation in metabolic ability. The aim of the current study was to investigate the effects
Autor:
Liran Tiosano, Nadav Levinger, Itay Chowers, Jaime Levy, Rivkah Lender, Tomer Batash, Elishai Assayag
Publikováno v:
European Journal of Ophthalmology. 32:2712-2718
Purpose To evaluate whether outcome of bevacizumab treatment in the first treated eye can guide the selection of compound for the second treated eye in patients with bilateral diabetic macular edema. Methods Demographic, clinical, and optical coheren
Autor:
F. Al Nimer, Fredrik Piehl, Maja Jagodic, C. Starvaggi Cucuzza, Ingrid Kockum, T. Frisell, Nicolas Ruffin
Publikováno v:
Multiple Sclerosis Journal. 27:3-133
Introduction: B cell depletion with rituximab (RTX) is associated with high treatment efficacy in relapsing-remitting multiple sclerosis (RRMS), with low risk of rebound phenomena with treatment interruptions, but also increased risk of mainly bacter
Autor:
Fabiola Paiar, Riccardo Morganti, Emanuele Neri, Angiolo Gadducci, Michela Gabelloni, Roberto Mattioni, Francesca Orlandi, Amelia Barcellini, Sabina Giusti, Concetta Laliscia
Publikováno v:
Tumori Journal. 108:376-385
Objective: To assess prognostic factors by analyzing clinical and radiomic data of patients with locally advanced cervical cancer (LACC) treated with definitive concurrent cisplatin-based chemoradiotherapy (CCRT) using magnetic resonance imaging (MRI
Publikováno v:
Clinical EEG and Neuroscience. 53:184-195
Objective. This study aimed to investigate the effect of bilateral transcranial direct current stimulation (tDCS) on the electroencephalography (EEG) amplitude and coherence in male patients with opioid use disorder (OUD), who were under methadone th
Publikováno v:
Am Surg
Background Talimogene laherparepvec (TVEC) is an injectable attenuated oncolytic herpes simplex virus (HSV-1) used in the treatment of loco regionally metastatic melanoma. Lesions managed by TVEC are generally considered unresectable at time of initi
Publikováno v:
Journal of Pharmacy Practice. 35:903-910
Background: Pharmacists routinely interpret and optimize tobramycin dosing for people with cystic fibrosis (PwCF). Objectives: To determine the impact of tobramycin therapeutic drug monitoring (TDM) education on pharmacist dose recommendations, and t